Skip to Main Content

Author Details

Mark H Ginsberg
University of California
1972
406
120
PMIDPaper TitleJournal TitlePublished Year
37068592Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography.J Thromb Haemost2023
37598341IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function.Cell Rep2023
37974623Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.ACS Pharmacol Transl Sci2023
35715588Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.Transl Stroke Res2023
36349990β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.FASEB J2022
35721481The Connection Between Rap1 and Talin1 in the Activation of Integrins in Blood Cells.Front Cell Dev Biol2022
32777822Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling.Blood2021
33865854Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins.J Biol Chem2021
33837285Endothelial struts enable the generation of large lumenized blood vessels de novo.Nat Cell Biol2021
34596055Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.J Clin Invest2021
34043589Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation.J Clin Invest2021
34013885Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations.Elife2021
34166073Cerebral Cavernous Malformation: From Mechanism to Therapy.Circ Res2021
33104169Distinct integrin activation pathways for effector and regulatory T cell trafficking and function.J Exp Med2021
33301422Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.J Clin Invest2021
31475386Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling.J Leukoc Biol2020
31707128β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25<sup>hi</sup>FoxP3<sup>+</sup> Regulatory T Cells.Cell Mol Gastroenterol Hepatol2020
33243988A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.Nat Commun2020
33077644MARCH Proteins Mediate Responses to Antitumor Antibodies.J Immunol2020
32518959Talin-1 is the principal platelet Rap1 effector of integrin activation.Blood2020
32369751Signal Transduction: Physical Deformation of the Membrane Activates Integrins.Curr Biol2020
30442679Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.Blood2019
29946133Phenotypic characterization of murine models of cerebral cavernous malformations.Lab Invest2019
31217347Biomarkers of cavernous angioma with symptomatic hemorrhage.JCI Insight2019
31426861Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.Acta Neuropathol Commun2019
30988001Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem.J Cell Biol2019
30728328Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.JCI Insight2019
30605669High-Affinity Bent β<sub>2</sub>-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis.Cell Rep2019
29703862Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance.J Immunol2018
30242097Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.Blood Adv2018
29535192Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development.J Cell Biol2018
28012647CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis.Atherosclerosis2017
28487468Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.J Biol Chem2017
28495929Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking.Arterioscler Thromb Vasc Biol2017
28348273Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes.J Immunol2017
29033288The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human α<sub>V</sub>β<sub>3</sub> Integrin via Steric Hindrance.Structure2017
28970240Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.J Exp Med2017
28515282Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool.J Immunol2017
26945935Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability.J Biol Chem2016
27908736CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.Cancer Cell2016
27839947Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.Structure2016
27365391A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors.J Biol Chem2016
27207789The Rap1-RIAM-talin axis of integrin activation and blood cell function.Blood2016
27495221Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes.Diabetes2016
27578049Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.Nat Commun2016
26780829Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.Elife2016
25587038Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor.Blood2015
26278174An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.Structure2015
26498519RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes.Biochem Biophys Res Commun2015
26419705A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration.Nat Commun2015
  • 1 - 50 of 406

Recommended Authors

Joseph E Aslan
Oregon Health & Science University
Career Start Year 2005
Number of shared co-authors 1
Xiaowen Liang
The University of Texas MD Anderson Cancer Center
Career Start Year 2004
Number of shared co-authors 0
Shannon K Alford
National Cancer Institute
Career Start Year 2004
Number of shared co-authors 2
Vineet Gupta
Purdue University
Career Start Year 1999
Number of shared co-authors 1
Ricardo J Giordano
Institute of Chemistry, University of Sao Paulo
Career Start Year 1994
Number of shared co-authors 0
Bego??a Campos
The University of Cincinnati
Career Start Year 1994
Number of shared co-authors 0
Manish J Butte
University of California Los Angeles
Career Start Year 1994
Number of shared co-authors 1
Karen H Martin
West Virginia University Cancer Institute, West Virginia University
Career Start Year 1993
Number of shared co-authors 4
Estelle S Harris
University of Utah
Career Start Year 1993
Number of shared co-authors 0
Charles A Whittaker
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Career Start Year 1993
Number of shared co-authors 2
Thuy Nguyen
Mayo Clinic
Career Start Year 1993
Number of shared co-authors 0
Donna J Webb
Vanderbilt University
Career Start Year 1991
Number of shared co-authors 6
Fu-Yue Zeng
Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 1991
Number of shared co-authors 0
Bruce S Sachais
Clinical Services
Career Start Year 1991
Number of shared co-authors 1
Daniel I Simon
Case Western Reserve University
Career Start Year 1990
Number of shared co-authors 0
Anne R Bresnick
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 1
Jennifer Soto
Mayo Clinic
Career Start Year 1988
Number of shared co-authors 0
Willem H Ouwehand
University of Cambridge
Career Start Year 1984
Number of shared co-authors 0
Martin J Humphries
University of Manchester
Career Start Year 1983
Number of shared co-authors 2
Lawrence Shapiro
Zuckerman Mind Brain Behaviour Institute
Career Start Year 1982
Number of shared co-authors 0
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Career Start Year 1981
Number of shared co-authors 1
Brian Seed
Center for Computational and Integrative Biology, Massachusetts General Hospital
Career Start Year 1980
Number of shared co-authors 1
Steven A Krilis
University of NSW
Career Start Year 1979
Number of shared co-authors 0
Steven L Gonias
University of California san francisco
Career Start Year 1978
Number of shared co-authors 2
David J Carey
Geisinger Medical Center
Career Start Year 1977
Number of shared co-authors 0
Peter A Kiener
BioKien LLC
Career Start Year 1976
Number of shared co-authors 2
William G Carter
University of Colorado Anschutz Medical Campus
Career Start Year 1975
Number of shared co-authors 0
Magnus H????k
Texas A&M Health Science Center Institute of Biosciences and Technology
Career Start Year 1974
Number of shared co-authors 2
Frederick S Southwick
University of Florida College of Medicine
Career Start Year 1969
Number of shared co-authors 0
David Ginsburg
University of Michigan ann arbor
Career Start Year 1965
Number of shared co-authors 1

Collaborators

Jaewon Han
University of California
Co-authored papers 19
Stanley E D'Souza
Co-authored papers 10
Lawrence E Goldfinger
Cardeza Foundation for Hematologic Research, Thomas Jefferson University
Co-authored papers 9
Iain D Campbell
University of Oxford
Co-authored papers 9
Klaus Ley
Co-authored papers 9
Joan S Brugge
Co-authored papers 7
John T Chang
University of California San Diego
Co-authored papers 6
Sean P Polster
University of Chicago
Co-authored papers 5
Alan Rick Horwitz
Allen Institute for Cell Science
Co-authored papers 5
Brian L Yaspan
Genentech Inc.
Co-authored papers 4
Jacob R Haling
Genomics Institute of the Novartis Research Foundation
Co-authored papers 4
Malene Hansen
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
Celeste Ptak
Co-authored papers 3
Donald F Hunt
University of Virginia
Co-authored papers 3
Jeffrey Shabanowitz
University of Virginia
Co-authored papers 3
Susan S Taylor
University of California
Co-authored papers 2
Milton H Werner
Inhibikase Therapeutics Inc.
Co-authored papers 2
Jian Kang
Co-authored papers 2
Uri Seligsohn
Co-authored papers 2
Kang Zhang
College of Animal Science and Technology, Guangxi University
Co-authored papers 2
Sarah L Blair
University of California
Co-authored papers 2
Thomas Quertermous
Co-authored papers 2
Nicholas E Sherman
University of Virginia
Co-authored papers 2
Iftach Shaked
Co-authored papers 2
Peter M Henson
Co-authored papers 2
Jay W Fox
University of Virginia
Co-authored papers 2
Achim Obergfell
Novartis Pharma
Co-authored papers 2
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 2
Michael B Major
Washington University in St. Louis
Co-authored papers 2
Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 2
Release 1.2