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Author Details

Alpay B Seven
Stanford University School of Medicine
2011
24
16
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36411392Insights into distinct signaling profiles of the µOR activated by diverse agonists.Nat Chem Biol2023
36993214Time-resolved cryo-EM of G protein activation by a GPCR.bioRxiv2023
36087581Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.Neuron2022
35418682The tethered peptide activation mechanism of adhesion GPCRs.Nature2022
36396979Structure determination of inactive-state GPCRs with a universal nanobody.Nat Struct Mol Biol2022
36171289Bespoke library docking for 5-HT<sub>2A</sub> receptor agonists with antidepressant activity.Nature2022
34194039G-protein activation by a metabotropic glutamate receptor.Nature2021
33836586Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.Proc Natl Acad Sci U S A2021
34087182Structure of the visual signaling complex between transducin and phosphodiesterase 6.Mol Cell2021
34194040Asymmetric activation of the calcium-sensing receptor homodimer.Nature2021
32126208Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.Cell Rep2020
33007200Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.Mol Cell2020
32946782Structure of a Hallucinogen-Activated Gq-Coupled 5-HT<sub>2A</sub> Serotonin Receptor.Cell2020
32580208Structures of metabotropic GABA<sub>B</sub> receptor.Nature2020
29564464Vitamin E-based glycoside amphiphiles for membrane protein structural studies.Org Biomol Chem2018
28858288Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion.Nat Protoc2017
29619178Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study.Chem Sci2017
27213521Functional synergy between the Munc13 C-terminal C1 and C2 domains.Elife2016
27926833Conformational Plasticity in the Transsynaptic Neurexin-Cerebellin-Glutamate Receptor Adhesion Complex.Structure2016
26030874Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.Nat Struct Mol Biol2015
23258414Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release.Science2013
23918375Prevalent mechanism of membrane bridging by synaptotagmin-1.Proc Natl Acad Sci U S A2013
21112337NMR structure and calcium-binding properties of the tellurite resistance protein TerD from Klebsiella pneumoniae.J Mol Biol2011
21765933Membrane bridging and hemifusion by denaturated Munc18.PLoS One2011
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Collaborators

Stanford University School of Medicine
Co-authored papers 16
Stanford University School of Medicine
Co-authored papers 9
University of Texas Southwestern Medical Center
Co-authored papers 7
Co-authored papers 4
Stanford University School of Medicine
Co-authored papers 4
UNC Chapel Hill School of Medicine
Co-authored papers 4
University of North Carolina at Chapel Hill
Co-authored papers 3
University of North Carolina School of Medicine
Co-authored papers 3
Stanford University School of Medicine
Co-authored papers 2
Eshelman School of Pharmacy, University of North Carolina
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
University of North Carolina School of Medicine
Co-authored papers 2
Stanford University
Co-authored papers 1
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
ETH Zurich
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Co-authored papers 1
Stanford University
Co-authored papers 1
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 1
University of North Carolina School of Medicine
Co-authored papers 1
University of North Carolina School of Medicine
Co-authored papers 1
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
University of North Carolina at Chapel Hill
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Bijvoet Center for Biomolecular Research, Utrecht University
Co-authored papers 1
Stanford University School of Medicine, Stanford University
Co-authored papers 1
University of North Carolina School of Medicine
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UNC School of Medicine
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School of Pharmacy, University of Wisconsin-Madison
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