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Author Details

Paula L Hoffman
University of Colorado
1972
204
51
PMIDPaper TitleJournal TitlePublished Year
34274109Sex Differences in the Brain Transcriptome Related to Alcohol Effects and Alcohol Use Disorder.Biol Psychiatry2022
35368676Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel.Front Genet2022
36386206The role of the type 7 adenylyl cyclase isoform in alcohol use disorder and depression.Front Pharmacol2022
36186443Evaluation and characterization of expression quantitative trait analysis methods in the Hybrid Rat Diversity Panel.Front Genet2022
32893479A long non-coding RNA (Lrap) modulates brain gene expression and levels of alcohol consumption in rats.Genes Brain Behav2021
33682145Effects of acetate on cerebral blood flow, systemic inflammation, and behavior in alcohol use disorder.Alcohol Clin Exp Res2021
32197424Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research.Biomedicines2020
33117893Controlling the "Opioid Epidemic": A Novel Chemical Entity (NCE) to Reduce or Supplant Opiate Use for Chronic Pain.J Psychiatr Brain Sci2020
31228159Networking in Biology: The Hybrid Rat Diversity Panel.Methods Mol Biol2019
31386214Effects of Alcohol and Acetate on Cerebral Blood Flow: A Pilot Study.Alcohol Clin Exp Res2019
29196862Voluntary exposure to a toxin: the genetic influence on ethanol consumption.Mamm Genome2018
30157779Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse.BMC Genomics2018
29689131Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism.Alcohol Clin Exp Res2018
27933531Using Baseline Transcriptional Connectomes in Rat to Identify Genetic Pathways Associated with Predisposition to Complex Traits.Methods Mol Biol2017
28740086Novel Molecule Exhibiting Selective Affinity for GABA<sub>A</sub> Receptor Subtypes.Sci Rep2017
27401171Uncovering the liver's role in immunity through RNA co-expression networks.Mamm Genome2016
27158117A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain.Eur J Pharmacol2016
25559016Influence of sex on genetic regulation of "drinking in the dark" alcohol consumption.Mamm Genome2015
26183165The sequenced rat brain transcriptome--its use in identifying networks predisposing alcohol consumption.FEBS J2015
24961585Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains.Alcohol Clin Exp Res2014
25063298The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations.Nucleic Acids Res2014
25160899Genetics of gene expression characterizes response to selective breeding for alcohol preference.Genes Brain Behav2014
23278386Genetic markers of comorbid depression and alcoholism in women.Alcohol Clin Exp Res2013
24141171The neurobiology of alcohol consumption and alcoholism: an integrative history.Pharmacol Biochem Behav2013
23894363Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption.PLoS One2013
21895709The biometric measurement of alcohol consumption.Alcohol Clin Exp Res2012
22424112Transducing emotionality: the role of adenylyl cyclases.Biol Psychiatry2012
21184165Genetical genomic analysis of complex phenotypes using the PhenoGen website.Behav Genet2011
21481845Sex-specific role for adenylyl cyclase type 7 in alcohol dependence.Biol Psychiatry2011
21054686Using the Phenogen website for 'in silico' analysis of morphine-induced analgesia: identifying candidate genes.Addict Biol2011
21185315A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission.Neuropharmacology2011
20008487Phosphorylation regulates removal of synaptic N-methyl-D-aspartate receptors after withdrawal from chronic ethanol exposure.J Pharmacol Exp Ther2010
20363852Type 7 adenylyl cyclase-mediated hypothalamic-pituitary-adrenal axis responsiveness: influence of ethanol and sex.J Pharmacol Exp Ther2010
19874574Genetical genomic determinants of alcohol consumption in rats and humans.BMC Biol2009
18550690Genomic insights into acute alcohol tolerance.J Pharmacol Exp Ther2008
23584876Expression quantitative trait loci and the PhenoGen database.Alcohol Res Health2008
20729980How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective.Alcohol Res Health2008
18563486The genomic determinants of alcohol preference in mice.Mamm Genome2008
17760997The PhenoGen informatics website: tools for analyses of complex traits.BMC Genet2007
16573589DNA microarray and proteomic strategies for understanding alcohol action.Alcohol Clin Exp Res2006
17010133Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice.Alcohol Clin Exp Res2006
17135423A sex-specific role of type VII adenylyl cyclase in depression.J Neurosci2006
16783646Candidate genes and their regulatory elements: alcohol preference and tolerance.Mamm Genome2006
16618939Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.Proc Natl Acad Sci U S A2006
15770104Effect of ethanol on DARPP-32 phosphorylation in transgenic mice that express human type VII adenylyl cyclase in brain.Alcohol Clin Exp Res2005
15849020Gene expression in animals with different acute responses to ethanol.Addict Biol2005
16088983World Health Organization/International Society for Biomedical Research on Alcoholism study on state and trait markers of alcohol use and dependence: back to the future.Alcohol Clin Exp Res2005
14690524Phosphatidylinositol 3'-OH kinase and protein kinase A pathways mediate the anti-apoptotic effect of pituitary adenylyl cyclase-activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol.J Neurochem2004
12805289Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors.J Neurosci2003
14696310NMDA receptors in alcoholism.Int Rev Neurobiol2003
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Collaborators

Boris Tabakoff
University of Colorado Health Science Center
Co-authored papers 169
Sanjiv V Bhave
University of Colorado at Denver and Health Sciences Center
Co-authored papers 21
Katerina Kechris
Co-authored papers 12
Kathleen A Grant
Oregon National Primate Research Center, Oregon Health and Science University.
Co-authored papers 8
John B Whitfield
Co-authored papers 4
John K Belknap
Oregon Health & Science University
Co-authored papers 4
Tamara J Phillips
Oregon Health & Science University
Co-authored papers 3
Robert W Williams
Mayo Clinic
Co-authored papers 3
Michael F Miles
Virginia Commonwealth University
Co-authored papers 3
Robert Hitzemann
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 3
John C Crabbe
Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 2
Leslie Reinlib
Co-authored papers 2
James M Sikela
University of Colorado
Co-authored papers 2
Howard J Edenberg
Indiana University School of Medicine
Co-authored papers 1
Christine C Wu
University of Washington
Co-authored papers 1
Matthias Heinig
Co-authored papers 1
Erik J MacLaren
Wellcome Trust Sanger Institute
Co-authored papers 1
Bernd Schnabl
University of California San Diego
Co-authored papers 1
Wenhua Ren
University of Colorado Denver
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Denesa R Lockwood
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 1
Anis Karimpour-Fard
University of Colorado
Co-authored papers 1
Chris Downing
Institute for Behavioral Genetics, University of Colorado
Co-authored papers 1
Marcella Rietschel
Central Institute of Mental Health, University of Mannheim
Co-authored papers 1
Megan K Mulligan
University of Tennessee Health Science Center.
Co-authored papers 1
Gregg E Homanics
University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Co-authored papers 1
Samuel W French
Co-authored papers 1
Hidekazu Tsukamoto
University of Michigan ann arbor
Co-authored papers 1
Jonathan R Pollack
Stanford University School of Medicine
Co-authored papers 1
Young H Kim
Stanford University
Co-authored papers 1
Release 1.2