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Author Details

Matthew C Altman
University of Washington School of Medicine, Seattle Benaroya Research Institute
2007
58
19
PMIDPaper TitleJournal TitlePublished Year
36223848Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial.J Allergy Clin Immunol2023
37460024Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy.J Allergy Clin Immunol2023
37212596Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma.Am J Respir Crit Care Med2023
37140544Kimma: flexible linear mixed effects modeling with kinship covariance for RNA-seq data.Bioinformatics2023
37001649Type 2 inflammation reduces SARS-CoV-2 replication in the airway epithelium in allergic asthma through functional alteration of ciliated epithelial cells.J Allergy Clin Immunol2023
37327781Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients.Cell Rep Med2023
36649800What Have Mechanistic Studies Taught Us About Childhood Asthma?J Allergy Clin Immunol Pract2023
36608946Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis.Lancet Planet Health2023
36708815Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.J Allergy Clin Immunol2023
36638096Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.PLoS Genet2023
36754293A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome.J Allergy Clin Immunol2023
3486281917q12-q21 variants interact with early-life exposures to modify asthma risk in Black children.Clin Exp Allergy2022
35381269Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.J Allergy Clin Immunol2022
35606880Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.Genome Med2022
35666868DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma.Proc Natl Acad Sci U S A2022
35413355Eosinophil-mediated suppression and anti-IL-5 enhancement of plasmacytoid dendritic cell interferon responses in asthma.J Allergy Clin Immunol2022
35964610Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial.Lancet2022
35149044Seasonal airway microbiome and transcriptome interactions promote childhood asthma exacerbations.J Allergy Clin Immunol2022
35027395Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.Eur Respir J2022
33314187Extracellular vesicle microRNAs as predictors of response to omalizumab in chronic spontaneous urticaria.Allergy2021
33683705A consequentialist argument for considering age in triage decisions during the coronavirus pandemic.Bioethics2021
33713771Endotype of allergic asthma with airway obstruction in urban children.J Allergy Clin Immunol2021
33624743BloodGen3Module: blood transcriptional module repertoire analysis and visualization using R.Bioinformatics2021
33712279Cockroach-induced IL9, IL13, and IL31 expression and the development of allergic asthma in urban children.J Allergy Clin Immunol2021
34675193Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.Nat Commun2021
34519110Unique basophil microRNA signature in chronic spontaneous urticaria patients who respond to omalizumab.Clin Exp Allergy2021
34691392Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children.Clin Transl Allergy2021
34629083Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.Genome Med2021
34531561Ignition sequence start: epithelial allergen sensing and regulation of the allergic inflammatory response.Nat Immunol2021
34019912Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.J Allergy Clin Immunol2021
34246435Management Strategies to Reduce Exacerbations in non-T2 Asthma.J Allergy Clin Immunol Pract2021
34282143Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.Nat Commun2021
32169380Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen.J Allergy Clin Immunol2020
31888785A 71-year-old man with recurrent pulmonary mycobacterial avium complex infections and lymphopenia.Allergy Asthma Proc2020
33377660Definition of erythroid cell-positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection.Clin Transl Med2020
32736569A modular framework for the development of targeted Covid-19 blood transcript profiling panels.J Transl Med2020
32246831Human airway epithelial cells express a functional IL-5 receptor.Allergy2020
30962590Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children.Nat Immunol2019
31437129Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.J Clin Invest2019
30979657Reply.J Allergy Clin Immunol2019
29111217Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.J Allergy Clin Immunol2018
29945814Reply.J Allergy Clin Immunol2018
29518416Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma.J Allergy Clin Immunol2018
29377961Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling.PLoS One2018
29106997Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function.J Allergy Clin Immunol2018
27986392Solving Immunology?Trends Immunol2017
28279664Combination omalizumab and mepolizumab therapy for refractory allergic bronchopulmonary aspergillosis.J Allergy Clin Immunol Pract2017
28322850Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.J Allergy Clin Immunol2017
28179497Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy.J Immunol2017
28504594A Deep Dive into Asthma Transcriptomics. Lessons from U-BIOPRED.Am J Respir Crit Care Med2017
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