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Author Details

Mark Akeson
University of California
1989
70
38
PMIDPaper TitleJournal TitlePublished Year
34728536Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing.RNA2022
36203024Advances in nanopore direct RNA sequencing.Nat Methods2022
35244721Nanopore ReCappable sequencing maps SARS-CoV-2 5' capping sites and provides new insights into the structure of sgRNAs.Nucleic Acids Res2022
32918735Unfolding and Translocation of Proteins Through an Alpha-Hemolysin Nanopore by ClpXP.Methods Mol Biol2021
33851162A new SARS-CoV-2 lineage that shares mutations with known Variants of Concern is rejected by automated sequence repository quality control.bioRxiv2021
33758101miRNA-independent function of long noncoding pri-miRNA loci.Proc Natl Acad Sci U S A2021
34618430Direct Nanopore Sequencing of Individual Full Length tRNA Strands.ACS Nano2021
34446532Synthesis of modified nucleotide polymers by the poly(U) polymerase Cid1: application to direct RNA sequencing on nanopores.RNA2021
34146471A community challenge to evaluate RNA-seq, fusion detection, and isoform quantification methods for cancer discovery.Cell Syst2021
34085238Adaptation of Human Ribosomal RNA for Nanopore Sequencing of Canonical and Modified Nucleotides.Methods Mol Biol2021
34047695Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of <i>Aim2</i>.Elife2021
33467183Real-Time Culture-Independent Microbial Profiling Onboard the International Space Station Using Nanopore Sequencing.Genes (Basel)2021
32686750Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes.Nat Biotechnol2020
31936690Off Earth Identification of Bacterial Populations Using 16S rDNA Nanopore Sequencing.Genes (Basel)2020
31819268Author Correction: Nanopore native RNA sequencing of a human poly(A) transcriptome.Nat Methods2020
31095620Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing.PLoS One2019
29553574Linear assembly of a human centromere on the Y chromosome.Nat Biotechnol2018
28722025Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells.Nat Commun2017
28218897Mapping DNA methylation with high-throughput nanopore sequencing.Nat Methods2017
27153276Author response to John Kasianowicz and Sergey Bezrukov.Nat Biotechnol2016
27964738Erratum to: The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community.Genome Biol2016
27887629The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community.Genome Biol2016
27153285Three decades of nanopore sequencing.Nat Biotechnol2016
25686389Improved data analysis for the MinION nanopore sequencer.Nat Methods2015
26157798Capture, Unfolding, and Detection of Individual tRNA Molecules Using a Nanopore Device.Front Bioeng Biotechnol2015
25402970Discrimination among protein variants using an unfoldase-coupled nanopore.ACS Nano2014
25347819Nanopores discriminate among five C5-cytosine variants in DNA.J Am Chem Soc2014
23376966Unfoldase-mediated protein translocation through an α-hemolysin nanopore.Nat Biotechnol2013
24167260Error rates for nanopore discrimination among cytosine, methylcytosine, and hydroxymethylcytosine along individual DNA strands.Proc Natl Acad Sci U S A2013
23705688Kinetic mechanism of translocation and dNTP binding in individual DNA polymerase complexes.J Am Chem Soc2013
22378784Direct observation of translocation in individual DNA polymerase complexes.J Biol Chem2012
23101437Dynamics of the translocation step measured in individual DNA polymerase complexes.J Am Chem Soc2012
22334048Automated forward and reverse ratcheting of DNA in a nanopore at 5-ÿ precision.Nat Biotechnol2012
21362617Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection.J Biol Chem2011
20871614Replication of individual DNA molecules under electronic control using a protein nanopore.Nat Nanotechnol2010
21121604Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase.J Am Chem Soc2010
19275265Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanopore.J Am Chem Soc2009
19338283Electronic control of DNA polymerase binding and unbinding to single DNA molecules.ACS Nano2009
19489560Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution.ACS Nano2009
19164022Feedback control of a DNA molecule tethered in a nanopore to repeatedly probe DNA-binding enzymes.Annu Int Conf IEEE Eng Med Biol Soc2008
17339846Single-molecule analysis of DNA-protein complexes using nanopores.Nat Methods2007
18654412Sequence-specific detection of individual DNA polymerase complexes in real time using a nanopore.Nat Nanotechnol2007
17118144Cheminformatics methods for novel nanopore analysis of HIV DNA termini.BMC Bioinformatics2006
15585125Nanopore cheminformatics.DNA Cell Biol2004
12547778Highly accurate classification of Watson-Crick basepairs on termini of single DNA molecules.Biophys J2003
12582251Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules.Nucleic Acids Res2003
12470736Biosensors for DNA sequence detection.Curr Opin Chem Biol2002
12210162Evaluation of nanopores as candidates for electronic analyte detection.Electrophoresis2002
11447062New DNA sequencing methods.Annu Rev Biomed Eng2001
11231558Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel.Nat Biotechnol2001
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Collaborators

Northeastern University
Co-authored papers 21
UC Santa Cruz Genomics Institute, University of California
Co-authored papers 9
Genomics Institute, University of California Santa Cruz
Co-authored papers 5
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Washington
Co-authored papers 1
Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Co-authored papers 1
Liver Center and Diabetes Center, University of California san francisco
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
National Institute of Neurological Disorders and Stroke, National Institute of Health
Co-authored papers 1
Co-authored papers 1
The Genome Institute, Washington University School of Medicine
Co-authored papers 1
IBM T.J. Watson Research Center
Co-authored papers 1
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Ontario Institute for Cancer Research
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Gies College of Business, University of Illinois at Urbana-Champaign.
Co-authored papers 1
University of California san francisco
Co-authored papers 1
National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 1
National Institute of Standards and Technology
Co-authored papers 1
Bill & Melinda Gates Foundation
Co-authored papers 1
Biomolecular Engineering and UC Santa Cruz Genome Institute, University of California
Co-authored papers 1
Center for Digital Medicine, Heinrich Heine University Dusseldorf
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1