Author details

Full Name

Michael B Brenner

Affiliation

ORCID

Career Start Year

1984

Papers

306

H Index

107

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37292637	Adipocytes regulate fibroblast function, and their loss contributes to fibroblast dysfunction in inflammatory diseases.	bioRxiv	2023
37791989	Associations between rheumatoid arthritis clinical factors with synovial cell types and states.		2023
37461737	Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.	bioRxiv	2023
37066336	The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis.	bioRxiv	2023
36993527	Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium.	bioRxiv	2023
36993194	Mapping the dynamic genetic regulatory architecture of <i>HLA</i> genes at single-cell resolution.	medRxiv	2023
37506196	Clonally expanded CD38 cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis.		2023
35148199	SLAMF7 engagement superactivates macrophages in acute and chronic inflammation.	Science immunology	2022
35704599	Granzyme K<sup>+</sup> CD8 T cells form a core population in inflamed human tissue.	Sci Transl Med	2022
35212719	High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership.	Rheumatology (Oxford)	2022
34651581	Fibroblast pathology in inflammatory diseases.	Journal of Clinical Investigation	2021
33911232	Fibroblasts as immune regulators in infection, inflammation and cancer.	Nature Reviews Immunology	2021
33462452	Distinct metabolic programs established in the thymus control effector functions of Î³Î´ T cell subsets in tumor microenvironments.	Nat Immunol	2021
32516575	Distinct iNKT Cell Populations Use IFNÎ³ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis.		2020
32268091	A Two-Cell Model for IL-1Î² Release Mediated by Death-Receptor Signaling.	Cell Reports	2020
32079724	CUX1 and IÎºBÎ¶ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts.	Proc Natl Acad Sci U S A	2020
32139419	Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress.	Ann Rheum Dis	2020
32253314	Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.	Proc Natl Acad Sci U S A	2020
32154791	Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-Î³ in NK cells.	J Clin Invest	2020
32637608	Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.	Sci Adv	2020
31304630	Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1.	EMBO Journal	2019
30429159	Plateletpheresis-associated lymphopenia in frequent platelet donors.	Blood	2019
31142839	Distinct fibroblast subsets drive inflammation and damage in arthritis.	Nature	2019
30876808	Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation.		2019
30737409	Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions.	Nat Commun	2019
31068444	HBEGF<sup>+</sup> macrophages in rheumatoid arthritis induce fibroblast invasiveness.	Sci Transl Med	2019
31209404	The immune cell landscape in kidneys of patients with lupus nephritis.	Nat Immunol	2019
30728493	Author Correction: Î³Î´ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.	Nature Immunology	2019
31536480	PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.	JCI Insight	2019
31409923	Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis.	Nat Immunol	2019
29592961	Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Infection.	Journal of Immunology	2018
28984647	Functional genomics of stromal cells in chronic inflammatory diseases.	Curr Opin Rheumatol	2018
30224362	Innate T Cells Govern Adipose Tissue Biology.	Journal of Immunology	2018
30013183	High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction.	Nat Genet	2018
30333237	Mixed-effects association of single cells identifies an expanded effector CD4<sup>+</sup> T cell subset in rheumatoid arthritis.	Sci Transl Med	2018
29996944	Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue	Arthritis Res Ther	2018
30420624	Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.	Nature Immunology	2018
29670241	Î³Î´ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.	Nature Immunology	2018
29476097	Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.	Nat Commun	2018
28150777	Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.	Nature	2017
28758901	Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.	Journal of Clinical Investigation	2017
28716901	Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface.	Proceedings of the National Academy of Sciences of the United States of America	2017
27855278	Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration.	American Journal of Pathology	2017
28228283	Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity.	Immunity	2017
28228280	Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators.	Immunity	2017
27593966	iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy.		2016
27183648	Pillars Article: A Functional T3 Molecule Associated with a Novel Heterodimer on the Surface of Immature Human Thymocytes. Nature. 1986. 322: 179-181.	Journal of Immunology	2016
27183647	Pillars Article: Identification of a Putative Second T-cell Receptor. Nature. 1986. 322: 145-149.	J Immunol	2016
27325790	A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair.	Journal of Cell Biology	2016
27457886	Activation strategies for invariant natural killer T cells.	Immunogenetics	2016