Author details

Full Name

Keiran Raine

Affiliation

Wellcome Sanger Institute

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34646017	Convergent somatic mutations in metabolism genes in chronic liver disease.	Nature	2021
34824211	Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture.	Nat Commun	2021
33004514	Extensive heterogeneity in somatic mutation and selection in the human bladder.	Science	2020
33028839	Framework for quality assessment of whole genome cancer sequences.	Nat Commun	2020
30849372	Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis.	Cell	2019
29656891	Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.	Cell	2018
29988082	Prediction of acute myeloid leukaemia risk in healthy individuals.	Nature	2018
29906452	Universal Patterns of Selection in Cancer and Somatic Tissues.	Cell	2018
30039366	Split-Read Indel and Structural Variant Calling Using PINDEL.	Methods Mol Biol	2018
29662167	Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.	Nat Genet	2018
29789651	Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.	Leukemia	2018
28810143	Genomic Evolution of Breast Cancer Metastasis and Relapse.	Cancer Cell	2017
28112740	A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.	Nat Genet	2017
28288110	HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.	Nat Med	2017
29056346	Universal Patterns of Selection in Cancer and Somatic Tissues.	Cell	2017
29074948	Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.	Nat Genet	2017
28945760	Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.	PLoS Genet	2017
27276561	Genomic Classification and Prognosis in Acute Myeloid Leukemia.	N Engl J Med	2016
27615322	Mutational signatures of ionizing radiation in second malignancies.	Nat Commun	2016
27588520	A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma.	Blood Cancer J	2016
27930809	ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data.	Curr Protoc Bioinformatics	2016
27930805	cgpCaVEManWrapper: Simple Execution of CaVEMan in Order to Detect Somatic Single Nucleotide Variants in NGS Data.	Curr Protoc Bioinformatics	2016
27498871	Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer.	Cell Rep	2016
27135926	Landscape of somatic mutations in 560 breast cancer whole-genome sequences.	Nature	2016
25730763	Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.	Nat Genet	2015
26647970	A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.	Nat Commun	2015
26678382	cgpPindel: Identifying Somatically Acquired Insertion and Deletion Events from Paired End Sequencing.	Curr Protoc Bioinformatics	2015
26099045	Subclonal diversification of primary breast cancer revealed by multiregion sequencing.	Nat Med	2015
26018901	Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.	Nat Genet	2015
24413735	RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.	Nat Genet	2014
25260652	Polygenic in vivo validation of cancer mutations using transposons.	Genome Biol	2014
25030888	C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency.	Genome Res	2014
25082706	Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.	Science	2014
24714652	Processed pseudogenes acquired somatically during cancer development.	Nat Commun	2014
23770606	Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.	Nat Genet	2013
24325359	Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.	N Engl J Med	2013
24182360	Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs.	Twin Res Hum Genet	2013
24148783	The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.	Genome Biol	2013
24030381	Clinical and biological implications of driver mutations in myelodysplastic syndromes.	Blood	2013
23630320	Single-cell paired-end genome sequencing reveals structural variation per cell cycle.	Nucleic Acids Res	2013
23599896	DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis.	Elife	2013
23778141	Whole exome sequencing of adenoid cystic carcinoma.	J Clin Invest	2013
22341448	Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer.	Cell	2012
22722201	The landscape of cancer genes and mutational processes in breast cancer.	Nature	2012
22514011	Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes.	J Pathol	2012
22608084	Mutational processes molding the genomes of 21 breast cancers.	Cell	2012
22608083	The life history of 21 breast cancers.	Cell	2012
22397650	Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.	N Engl J Med	2012
21248752	Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.	Nature	2011
21995386	Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.	N Engl J Med	2011

1 - 50 of 64

Ander Diaz-Navarro

Instituto Universitario de Oncologia (IUOPA), Universidad de Oviedo

Career Start Year 2018

Number of shared co-authors 12

Job van Riet

Erasmus MC Cancer Institute

Career Start Year 2017

Number of shared co-authors 5

Julian M Hess

Broad Institute of MIT and Harvard

Career Start Year 2015

Number of shared co-authors 11

Andrew M K Brown

Ontario Institute for Cancer Research

Career Start Year 2012

Number of shared co-authors 29

Richard de Borja

The Hospital for Sick Children

Career Start Year 2012

Number of shared co-authors 38

Andrew McPherson

Memorial Sloan Kettering Cancer Center

Career Start Year 2010

Number of shared co-authors 20

Christopher A Miller

Washington University School of Medicine

Career Start Year 2009

Number of shared co-authors 3

Joshua F McMichael

Washington University

Career Start Year 2009

Number of shared co-authors 5

Lixing Yang

University of Chicago, USA University of Chicago Comprehensive Cancer Center

Career Start Year 2008

Number of shared co-authors 11

Ken Chen

University of Texas MD Anderson Cancer Center

Career Start Year 2007

Number of shared co-authors 8

Paz Polak

McGill University

Career Start Year 2006

Number of shared co-authors 12

Jamie K Teer

H. Lee Moffitt Cancer Center and Research Institute

Career Start Year 2005

Number of shared co-authors 7

Abel Gonzalez-Perez

Universitat Pompeu Fabra

Career Start Year 2005

Number of shared co-authors 28

Joachim Weischenfeldt

University of Copenhagen

Career Start Year 2004

Number of shared co-authors 45

Chip Stewart

Broad Institute of MIT and Harvard

Career Start Year 2004

Number of shared co-authors 25

Olivier Harismendy

University of California

Career Start Year 2003

Number of shared co-authors 6

Sohrab P Shah

Memorial Sloan Kettering Cancer Center

Career Start Year 2003

Number of shared co-authors 47

Michael D McLellan

McDonnell Genome Institute, Washington University in St. Louis

Career Start Year 2003

Number of shared co-authors 14

David E Larson

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 2003

Number of shared co-authors 5

Benjamin J Raphael

Princeton University

Career Start Year 2003

Number of shared co-authors 23

Malachi Griffith

Washington University

Career Start Year 2003

Number of shared co-authors 17

Gad Getz

Broad Institute of the Massachusetts Institute of Technology and Harvard

Career Start Year 2000

Number of shared co-authors 48

Michael N Edmonson

St. Jude Children's Research Hospital

Career Start Year 1999

Number of shared co-authors 5

Nuria Lopez-Bigas

Universitat Pompeu Fabra

Career Start Year 1999

Number of shared co-authors 51

Carrie Sougnez

The Broad Institute of Harvard and MIT

Career Start Year 1998

Number of shared co-authors 29

Li Ding

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 1997

Number of shared co-authors 23

Robert S Fulton

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 1994

Number of shared co-authors 26

Jinghui Zhang

Changhai Hospital, Second Military Medical University

Career Start Year 1992

Number of shared co-authors 38

Elaine R Mardis

The Ohio State University

Career Start Year 1988

Number of shared co-authors 41

Matthew Meyerson

Broad Institute

Career Start Year 1983

Number of shared co-authors 43

row(s) 1 - 30 of 30

Adam Butler

Wellcome Sanger Institute

Co-authored papers 47

Peter J Campbell

Wellcome Sanger Institute

Co-authored papers 46

Michael R Stratton

Wellcome Sanger Institute

Co-authored papers 43

Jon Teague

Wellcome Sanger Institute

Co-authored papers 41

David Jones

Wellcome Sanger Institute

Co-authored papers 40

Andrew Menzies

Wellcome Sanger Institute

Co-authored papers 34

Phillip A Futreal

The University of Texas MD Anderson Cancer Center

Co-authored papers 33

Sarah O'Meara

Clinical Research Facility, Mercy University Hospital

Co-authored papers 27

Patrick S Tarpey

Wellcome Trust Sanger Institute

Co-authored papers 26

Peter Van Loo

The Francis Crick Institute

Co-authored papers 25

Serena Nik-Zainal

Early Cancer Institute, University of Cambridge

Co-authored papers 24

David C Wedge

Manchester Cancer Research Centre, University of Manchester

Co-authored papers 24

Jonathan Hinton

Inivata Ltd

Co-authored papers 23

Laura Mudie

Wellcome Trust Sanger Institute

Co-authored papers 19

Stuart McLaren

Wellcome Trust Sanger Institute

Co-authored papers 19

Ludmil B Alexandrov

Moores Cancer Center, university of california san diego

Co-authored papers 16

Rebecca Shepherd

Murdoch Children's Research Institute, Royal Children's Hospital

Co-authored papers 16

Chris Greenman

University of East Anglia

Co-authored papers 15

Inigo Martincorena

Wellcome Sanger Institute

Co-authored papers 15

Sarah Edkins

Co-authored papers 13

Lucy A Stebbings

Wellcome Trust Sanger Institute

Co-authored papers 13

Douglas F Easton

University of Cambridge

Co-authored papers 13

Susanna L Cooke

Institute of Cancer Sciences, University of Glasgow

Co-authored papers 13

Andrea L Richardson

Co-authored papers 12

Gunes Gundem

Memorial Sloan Kettering Cancer Center

Co-authored papers 12

Sara Widaa

Co-authored papers 12

Manasa Ramakrishna

Co-authored papers 12

Gemma Buck

Co-authored papers 11

Moritz Gerstung

German Cancer Research Centre DKFZ

Co-authored papers 11

Claire Hardy

Wellcome Sanger Institute

Co-authored papers 10

1 - 30

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