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Author Details

Gregory A Michelotti
Inc. Research Triangle Park
1987
87
38
PMIDPaper TitleJournal TitlePublished Year
37034709Untargeted metabolomics profiling in pediatric patients and adult populations indicates a connection between lipid imbalance and epilepsy.medRxiv2023
37526398Genetic and gut microbiome determinants of SCFA circulating and fecal levels, postprandial responses and links to chronic and acute inflammation.Gut Microbes2023
37023745The secondary bile acid isoursodeoxycholate correlates with post-prandial lipemia, inflammation, and appetite and changes post-bariatric surgery.Cell Rep Med2023
37017544Hepatic triglyceride content is intricately associated with numerous metabolites and biochemical pathways.Liver Int2023
35323708Metabolomic Profiles in Childhood and Adolescence Are Associated with Fetal Overnutrition.Metabolites2022
35736491Metabolome Alterations Linking Sugar-Sweetened Beverage Intake with Dyslipidemia in Youth: The Exploring Perinatal Outcomes among CHildren (EPOCH) Study.Metabolites2022
35629908Metabolomic Predictors of Dysglycemia in Two U.S. Youth Cohorts.Metabolites2022
36144194The Roles of Gut Microbiome and Plasma Metabolites in the Associations between ABO Blood Groups and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).Metabolites2022
36357675Rare and common genetic determinants of metabolic individuality and their effects on human health.Nat Med2022
33414548A cross-platform approach identifies genetic regulators of human metabolism and health.Nat Genet2021
33707775Plasma metabolites to profile pathways in noncommunicable disease multimorbidity.Nat Med2021
31279616Metabolomics reveals plausible interactive effects between dairy product consumption and metabolic syndrome in humans.Clin Nutr2020
33987620Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules.Netw Syst Med2020
31720734A prospective study of associations between in utero exposure to gestational diabetes mellitus and metabolomic profiles during late childhood and adolescence.Diabetologia2020
32751947Metabolite Profiles of the Relationship between Body Mass Index (BMI) Milestones and Metabolic Risk during Early Adolescence.Metabolites2020
32469399Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).Am J Clin Nutr2020
30850646Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.Nat Commun2019
30939782Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population.Metabolites2019
29305935Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.Gastroenterology2018
29381822Metabolomic response to coffee consumption: application to a three-stage clinical trial.J Intern Med2018
27913210TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.Free Radic Biol Med2017
28452488Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets.J Proteome Res2017
28427343Loss of pericyte smoothened activity in mice with genetic deficiency of leptin.BMC Cell Biol2017
25596181Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches.Gut2016
26403427Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.Dig Dis Sci2016
26474534Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis.Biochim Biophys Acta2016
26890135Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.Cell Death Dis2016
26718771Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation.Am J Physiol Gastrointest Liver Physiol2016
26970079Hedgehog regulates yes-associated protein 1 in regenerating mouse liver.Hepatology2016
26893476Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes.Cancer Res2016
25053716Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.Gut2015
26244980Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation.PLoS One2015
26590477Designing a broad-spectrum integrative approach for cancer prevention and treatment.Semin Cancer Biol2015
26454069Dysregulated metabolism contributes to oncogenesis.Semin Cancer Biol2015
26416247LGR5 is associated with tumor aggressiveness in papillary thyroid cancer.Oncotarget2015
26121577Correction: Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease.PLoS One2015
26070409Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease.J Hepatol2015
25989356NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.Am J Pathol2015
26029472Inflammatory models drastically alter tumor growth and the immune microenvironment in hepatocellular carcinoma.Sci Bull (Beijing)2015
25658689Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.PLoS One2015
25501551Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.Am J Physiol Gastrointest Liver Physiol2015
25524063Role of Fn14 in acute alcoholic steatohepatitis in mice.Am J Physiol Gastrointest Liver Physiol2015
25347994M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice.J Pharmacol Exp Ther2015
23913408Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.Hepatology2014
25121996Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism.Endocrinology2014
24493022Reply: To PMID 23913408.Hepatology2014
24416188TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice.PLoS One2014
24211274CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.Toxicol Appl Pharmacol2014
24173292Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.Gut2014
24164383Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.Alcohol Clin Exp Res2014
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Collaborators

Debra A Schwinn
Roy J. & Lucille A. Carver College of Medicine, University of Iowa
Co-authored papers 12
Tim D Spector
King's College London
Co-authored papers 4
Massimo Mangino
Co-authored papers 3
Claudia Langenberg
Co-authored papers 3
Katerina Kechris
Co-authored papers 3
Michael P Smith
Duke University Medical Center
Co-authored papers 3
Dana Dabelea
Co-authored papers 3
Nicholas J Wareham
Co-authored papers 3
Eric B Fauman
Co-authored papers 2
Ruifang Li-Gao
Co-authored papers 2
Nicola Segata
University of Trento
Co-authored papers 2
Jason W Locasale
Duke University
Co-authored papers 2
Eric Boerwinkle
Baylor College of Medicine
Co-authored papers 2
Marie-France Hivert
Co-authored papers 2
Praveen Surendran
Co-authored papers 2
Matthew D Hirschey
Duke Molecular Physiology Institute, Duke University School of Medicine
Co-authored papers 2
Emily Oken
Co-authored papers 2
Dennis O Mook-Kanamori
Co-authored papers 2
Kay-Tee Khaw
Co-authored papers 2
Paul C Kuo
University of South Florida Morsani College of Medicine
Co-authored papers 2
Brad Poore
Co-authored papers 2
Adam S Butterworth
British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge
Co-authored papers 2
Costas A Lyssiotis
Co-authored papers 2
Luca A Lotta
Co-authored papers 2
Ana M Valdes
University of Nottingham
Co-authored papers 2
John Danesh
Co-authored papers 2
Lee W Jones
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Christopher D Lascola
Duke Cancer Institute
Co-authored papers 1
Alanna C Morrison
Co-authored papers 1
Thomas E Carey
Kresge Hearing Research Institute, University of Michigan ann arbor
Co-authored papers 1
Release 1.2