| 37402863 | Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis. | Nature | 2023 |
| 37600222 | The critical role of mode of action studies in kinetoplastid drug discovery. | Front Drug Discov (Lausanne) | 2023 |
| 34531949 | Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity. | ACS Med Chem Lett | 2021 |
| 33691122 | Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial. | Cell Chem Biol | 2021 |
| 34471283 | Tres Cantos Open Lab: celebrating a decade of innovation in collaboration to combat endemic infectious diseases. | Nat Rev Drug Discov | 2021 |
| 34410327 | Surmounting structural barriers to tackle endemic infectious diseases. | J Exp Med | 2021 |
| 32292551 | New 8-Nitroquinolinone Derivative Displaying Submicromolar <i>in Vitro</i> Activities against Both <i>Trypanosoma brucei</i> and <i>cruzi</i>. | ACS Med Chem Lett | 2020 |
| 31967783 | The Q<sub>i</sub> Site of Cytochrome <i>b</i> is a Promiscuous Drug Target in <i>Trypanosoma cruzi</i> and <i>Leishmania donovani</i>. | ACS Infect Dis | 2020 |
| 32795774 | Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties. | Eur J Med Chem | 2020 |
| 32652409 | 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi. | Eur J Med Chem | 2020 |
| 32275825 | Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase. | ACS Infect Dis | 2020 |
| 29701144 | Current and Future Prospects of Nitro-compounds as Drugs for Trypanosomiasis and Leishmaniasis. | Curr Med Chem | 2019 |
| 31840685 | Fexinidazole for the treatment of human African trypanosomiasis. | Drugs Today (Barc) | 2019 |
| 31188540 | Substituted Aminoacetamides as Novel Leads for Malaria Treatment. | ChemMedChem | 2019 |
| 30894487 | Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. | Proc Natl Acad Sci U S A | 2019 |
| 30962368 | Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition. | Proc Natl Acad Sci U S A | 2019 |
| 30380837 | Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani. | ACS Infect Dis | 2019 |
| 29705579 | Melarsoprol Resistance in African Trypanosomiasis. | Trends Parasitol | 2018 |
| 29885575 | Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study. | Eur J Med Chem | 2018 |
| 30046105 | Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis. | Nature | 2018 |
| 30045874 | A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism. | Biochem J | 2018 |
| 30206344 | Author Correction: Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need. | Nat Rev Microbiol | 2018 |
| 30092366 | 8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases. | Eur J Med Chem | 2018 |
| 30221468 | Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions. | ChemMedChem | 2018 |
| 29844044 | Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals. | Antimicrob Agents Chemother | 2018 |
| 30655943 | Nongenotoxic 3-Nitroimidazo[1,2-<i>a</i>]pyridines Are NTR1 Substrates That Display Potent <i>in Vitro</i> Antileishmanial Activity. | ACS Med Chem Lett | 2018 |
| 30264983 | Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome. | ACS Infect Dis | 2018 |
| 29777624 | Characterisation of a putative glutamate 5-kinase from Leishmania donovani. | FEBS J | 2018 |
| 27798837 | Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. | ACS Infect Dis | 2017 |
| 28239154 | Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need. | Nat Rev Microbiol | 2017 |
| 28967262 | Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani. | ACS Infect Dis | 2017 |
| 29115999 | Screening a protein kinase inhibitor library against Plasmodium falciparum. | Malar J | 2017 |
| 28579611 | Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need. | Nat Rev Microbiol | 2017 |
| 26682963 | Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes. | J Antimicrob Chemother | 2016 |
| 26581221 | Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei. | J Antimicrob Chemother | 2016 |
| 27703008 | The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei. | J Biol Chem | 2016 |
| 27812217 | Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania. | PLoS Pathog | 2016 |
| 27631715 | Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy. | J Med Chem | 2016 |
| 27175479 | Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase. | PLoS Negl Trop Dis | 2016 |
| 27572976 | Drug resistance in eukaryotic microorganisms. | Nat Microbiol | 2016 |
| 27492267 | The N-myristoylome of Trypanosoma cruzi. | Sci Rep | 2016 |
| 27314305 | Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials. | J Med Chem | 2016 |
| 27215734 | The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis. | Elife | 2016 |
| 27281209 | Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis. | Nature | 2016 |
| 27020099 | Open Lab as a source of hits and leads against tuberculosis, malaria and kinetoplastid diseases. | Nat Rev Drug Discov | 2016 |
| 25367138 | Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei. | Mol Microbiol | 2015 |
| 26312902 | Arsenic, antimony, and Leishmania: has arsenic contamination of drinking water in India led to treatment- resistant kala-azar? | Lancet | 2015 |
| 26684831 | Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome. | PLoS Negl Trop Dis | 2015 |
| 26085270 | A novel multiple-stage antimalarial agent that inhibits protein synthesis. | Nature | 2015 |
| 25678015 | Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity. | Bioorg Med Chem | 2015 |