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Author Details

Patricia A Shaw
Princess Margaret Cancer Centre, University Avenue
1990
103
47
PMIDPaper TitleJournal TitlePublished Year
36943460Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.Cancer Immunol Immunother2023
33858678The Prevent Ovarian Cancer Program (POCP): Identification of women at risk for ovarian cancer using complementary recruitment approaches.Gynecol Oncol2021
32349388Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla-Site of Origin of Serous Carcinoma of the Ovary.Cancers (Basel)2020
31964625IL6 Induces an IL22<sup>+</sup> CD8<sup>+</sup> T-cell Subset with Potent Antitumor Function.Cancer Immunol Res2020
29521846International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines From the Special Techniques and Ancillary Studies Group.Int J Gynecol Pathol2019
31836588Heterogeneous alteration of the ERBB3-MYC axis associated with MEK inhibitor resistance in a <i>KRAS</i>-mutated low-grade serous ovarian cancer patient.Cold Spring Harb Mol Case Stud2019
31803363Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models.Oncotarget2019
31892360High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation.J Immunother Cancer2019
31741762Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer.Oncoimmunology2019
31530568Chromosomal Instability and mTORC1 Activation through PTEN Loss Contribute to Proteotoxic Stress in Ovarian Carcinoma.Cancer Res2019
31078521CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinoma.EBioMedicine2019
30659026<i>TP53</i> mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses.Int J Gynecol Cancer2019
29145543Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus-Related Cervical Carcinoma.JAMA Oncol2018
30232083Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study.Cancer Prev Res (Phila)2018
30042185Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap.J Med Genet2018
30144186Novel EPC1 gene fusions in endometrial stromal sarcoma.Genes Chromosomes Cancer2018
30065096Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.Clin Cancer Res2018
30108107A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium.Clin Cancer Res2018
30382883Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors.Genome Med2018
29416878Genomic profiling identifies <i>GPC5</i> amplification in association with sarcomatous transformation in a subset of uterine carcinosarcomas.J Pathol Clin Res2018
29458007A Genomically Characterized Collection of High-Grade Serous Ovarian Cancer Xenografts for Preclinical Testing.Am J Pathol2018
28062115Genotype-matched treatment for patients with advanced type I epithelial ovarian cancer (EOC).Gynecol Oncol2017
28165478A distinct innate lymphoid cell population regulates tumor-associated T cells.Nat Med2017
28221868Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition.J Clin Oncol2017
28398847Traceback: A Proposed Framework to Increase Identification and Genetic Counseling of BRCA1 and BRCA2 Mutation Carriers Through Family-Based Outreach.J Clin Oncol2017
28176205Correlation between germline mutations in MMR genes and microsatellite instability in ovarian cancer specimens.Fam Cancer2017
29042553Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma.Nat Commun2017
28729099Implementing a Cervical Sentinel Lymph Node Biopsy Program: Quality Improvement in Gynaecologic Oncology.J Obstet Gynaecol Can2017
28654427DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.Am J Surg Pathol2017
27601594Neoadjuvant Chemotherapy of Ovarian Cancer Results in Three Patterns of Tumor-Infiltrating Lymphocyte Response with Distinct Implications for Immunotherapy.Clin Cancer Res2017
25798842Loss of LKB1 and p53 synergizes to alter fallopian tube epithelial phenotype and high-grade serous tumorigenesis.Oncogene2016
27782854Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.Genome Med2016
27241111Prophylactic Gynecologic Specimens from Hereditary Cancer Carriers.Surg Pathol Clin2016
27100627Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics.Histopathology2016
26072440Cancer precursor lesions in the BRCA population at the time of prophylactic salpingo-oophorectomy: Accuracy of assessment and potential surrogate marker for prevention.Gynecol Oncol2015
26555178In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose.J Vis Exp2015
26775351Survival in women with ovarian cancer with and without microsatellite instability.Eur J Gynaecol Oncol2015
26189250Prognostic value of INPP4B protein immunohistochemistry in ovarian cancer.Eur J Gynaecol Oncol2015
24495259Review of findings in prophylactic gynaecological specimens in Lynch syndrome with literature review and recommendations for grossing.Histopathology2014
25528264The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells.J Ovarian Res2014
25349970Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study.Br J Cancer2014
25025451The histomorphology of Lynch syndrome-associated ovarian carcinomas: toward a subtype-specific screening strategy.Am J Surg Pathol2014
24338723Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.J Pathol2014
24336157Retinoblastoma pathway deregulatory mechanisms determine clinical outcome in high-grade serous ovarian carcinoma.Mod Pathol2014
24478985BRCA and Early Events in the Development of Serous Ovarian Cancer.Front Oncol2014
22899400Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas.J Pathol2013
24845429Specimen quality evaluation in Canadian biobanks participating in the COEUR repository.Biopreserv Biobank2013
23257159Long-term ovarian cancer survival associated with mutation in BRCA1 or BRCA2.J Natl Cancer Inst2013
22948899Feasibility of real time next generation sequencing of cancer genes linked to drug response: results from a clinical trial.Int J Cancer2013
22918161Endometrial sarcomas: an immunohistochemical and JAZF1 re-arrangement study in low-grade and undifferentiated tumors.Mod Pathol2013
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Collaborators

Blaise A Clarke
University of Toronto.
Co-authored papers 33
John R McLaughlin
University of Toronto Dalla Lana School of Public Health
Co-authored papers 8
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 8
Suzanne Kamel-Reid
Toronto General Hospital, University Health Network, University of Toronto
Co-authored papers 6
Cyril B Gilks
University of British Columbia
Co-authored papers 5
Robert A Soslow
Co-authored papers 5
David G Huntsman
University of British Columbia
Co-authored papers 5
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers 5
Philippe L Bedard
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Hal K Berman
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Stephen Welch
Victoria Hospital
Co-authored papers 4
Martin K??bel
University of Calgary
Co-authored papers 4
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 4
Jeff P Bruce
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Thomas J Hudson
Ontario Institute for Cancer Research
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Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 3
William D Foulkes
Segal Cancer Centre, Jewish General Hospital
Co-authored papers 3
Raymond H Kim
Cardiac Genome Clinic, The Hospital for Sick Children
Co-authored papers 3
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 3
David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers 3
Brenda L Gallie
The Eye Cancer Clinic, Princess Margaret Cancer Centre, Hospital for Sick Children
Co-authored papers 3
John D McPherson
Ontario Institute for Cancer Research
Co-authored papers 3
Douglas A Levine
Perlmutter Cancer Center
Co-authored papers 3
Andrew M K Brown
Ontario Institute for Cancer Research
Co-authored papers 3
Steve E Kalloger
University of British Columbia
Co-authored papers 3
Ghassan Allo
Henry Ford Hospital
Co-authored papers 3
Aaron Pollett
Mount Sinai Hospital
Co-authored papers 3
Joellen M Schildkraut
Rollins School of Public Health, Emory University
Co-authored papers 3
Helen Steed
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Release 1.2