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Author Details

David R Sherman
University of Washington
1987
116
52
PMIDPaper TitleJournal TitlePublished Year
36763530The human proton pump inhibitors inhibit <i>Mycobacterium tuberculosis</i> rifampicin efflux and macrophage-induced rifampicin tolerance.Proc Natl Acad Sci U S A2023
37017524A Novel Tool to Identify Bactericidal Compounds against Vulnerable Targets in Drug-Tolerant M. tuberculosis found in Caseum.mBio2023
36690861The Mycobacterium tuberculosis protein O-phosphorylation landscape.Nat Microbiol2023
35173157Early alveolar macrophage response and IL-1R-dependent T cell priming determine transmissibility of Mycobacterium tuberculosis strains.Nat Commun2022
36275024The evolving biology of Mycobacterium tuberculosis drug resistance.Front Cell Infect Microbiol2022
33367727Re-evaluation of a novel resistance mutation in eccC5 of the ESX-5 secretion system in ofloxacin-resistant Mycobacterium tuberculosis.J Antimicrob Chemother2021
34150934ODELAM: Rapid Sequence-independent Detection of Drug Resistance in <i>Mycobacterium tuberculosis</i> Isolates.Bio Protoc2021
34235667Experimental and Computational Workflow for RNA Sequencing in Mycobacterium tuberculosis : From Total RNA to Differentially Expressed Genes.Methods Mol Biol2021
33199862Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis.Nat Microbiol2021
33142108Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis.Cell Host Microbe2021
32401195ODELAM, rapid sequence-independent detection of drug resistance in isolates of <i>Mycobacterium tuberculosis</i>.Elife2020
31665359Nicotinamide Limits Replication of Mycobacterium tuberculosis and Bacille Calmette-Guérin Within Macrophages.J Infect Dis2020
32075921Reply to Vargas and Farhat: <i>Mycobacterium tuberculosis glpK</i> mutants in human tuberculosis.Proc Natl Acad Sci U S A2020
32738213Rapid, direct detection of bacterial topoisomerase 1-DNA adducts by RADAR/ELISA.Anal Biochem2020
32571828Rapidly Correcting Frameshift Mutations in the Mycobacterium tuberculosis <i>orn</i> Gene Produce Reversible Ethambutol Resistance and Small-Colony-Variant Morphology.Antimicrob Agents Chemother2020
32926793Genetic Diversity in <i>Mycobacterium tuberculosis</i> Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease.Annu Rev Genet2020
30449724Inhibiting the Evolution of Antibiotic Resistance.Mol Cell2019
31719182Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis.mBio2019
31488707Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance.Proc Natl Acad Sci U S A2019
30753612Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance.J Infect Dis2019
30146391Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination.Cell Host Microbe2018
30157391Bacterial Factors That Predict Relapse after Tuberculosis Therapy.N Engl J Med2018
30021818Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection.Clin Microbiol Rev2018
28061953Advances in basic and translational tuberculosis research: Proceedings of the first meeting of RePORT international.Tuberculosis (Edinb)2017
28414762Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection.PLoS One2017
28436493An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology.Sci Rep2017
29281637Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose.PLoS Genet2017
28775896Comprehensive definition of human immunodominant CD8 antigens in tuberculosis.NPJ Vaccines2017
28618268Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis.Cell Host Microbe2017
26822628Towards understanding the biological function of the unusual chaperonin Cpn60.1 (GroEL1) of Mycobacterium tuberculosis.Tuberculosis (Edinb)2016
27505158Nonpathogenic SIV and Pathogenic HIV Infections Associate with Disparate Innate Cytokine Signatures in Response to Mycobacterium bovis BCG.PLoS One2016
27573104Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis.Nat Microbiol2016
25322074DosS Is required for the complete virulence of mycobacterium tuberculosis in mice with classical granulomatous lesions.Am J Respir Cell Mol Biol2015
26618656Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis.PLoS Comput Biol2015
26771003A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis.ACS Infect Dis2015
25857935Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.Tuberculosis (Edinb)2015
25977815A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis.Sci Data2015
25730547The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence.Am J Respir Crit Care Med2015
25581030The DNA-binding network of Mycobacterium tuberculosis.Nat Commun2015
24409094Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch.PLoS Biol2014
25287926Mycobacterium tuberculosis strains lacking surface lipid phthiocerol dimycocerosate are susceptible to killing by an early innate host response.Infect Immun2014
25232098A high-resolution network model for global gene regulation in Mycobacterium tuberculosis.Nucleic Acids Res2014
25380655Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network.Genome Biol2014
25099260Agents of change - concepts in Mycobacterium tuberculosisâ¿¿Ser/Thr/Tyr phosphosignalling.Mol Microbiol2014
24954008Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.Chem Biol2014
24927537Mycobacterium tuberculosis supports protein tyrosine phosphorylation.Proc Natl Acad Sci U S A2014
23125364Global analysis of mRNA stability in Mycobacterium tuberculosis.Nucleic Acids Res2013
24309377Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.Proc Natl Acad Sci U S A2013
24086479Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis.PLoS One2013
24244263A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis.PLoS One2013
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Collaborators

Kristine M Guinn
Harvard T. H. Chan School of Public Health
Co-authored papers 7
Nitin S Baliga
Institute for Systems Biology
Co-authored papers 6
David M Lewinsohn
Oregon Health and Science University
Co-authored papers 4
Nathan D Price
Institute for Systems Biology
Co-authored papers 4
William Henry Boom
Case Western Reserve University and University Hospitals Cleveland Medical Center
Co-authored papers 3
John D Aitchison
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 3
Deborah A Lewinsohn
Oregon Health and Science University
Co-authored papers 2
JoAnne L Flynn
Co-authored papers 2
Meghan E Cansler
Oregon Health and Science University
Co-authored papers 2
Harriet Mayanja-Kizza
Case Western Reserve University
Co-authored papers 2
Megan D Null
Oregon Health and Science University
Co-authored papers 2
Gwendolyn M Swarbrick
Oregon Health and Science University
Co-authored papers 2
Nadia A Golden
Co-authored papers 2
Andrew Frando
Seattle Children's Research Institute
Co-authored papers 2
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
Tianhua Niu
Co-authored papers 2
Thurston Herricks
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 2
Jinhee Lee
University of Massachusetts Medical School
Co-authored papers 1
Joy Baseke
Busitema University
Co-authored papers 1
Fred D Mast
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 1
Kostantin Kiianitsa
University of Washington
Co-authored papers 1
Jeremy Zucker
Pacific Northwest National Laboratory
Co-authored papers 1
Carolyn R Bertozzi
Stanford University
Co-authored papers 1
William W Kwok
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Sarah Zalwango
School of Public Health, Makerere University
Co-authored papers 1
Keith Chervenak
Case Western Reserve University
Co-authored papers 1
Wen-Han Yu
Co-authored papers 1
Thomas R Ioerger
Co-authored papers 1
Marisa Frieder
Portland VA Medical Center, 3710 U.S. Veterans Hospital Road
Co-authored papers 1
Kanury V S Rao
Translational Health Science and Technology Institute
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