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Author Details
Full Name
Denis C Shields
Affiliation
Conway Institute of Biomolecular and Biomedical Research, University College Dublin
ORCID
Career Start Year
1987
Papers
191
H Index
52
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37049968
Relationship between Protein Digestibility and the Proteolysis of Legume Proteins during Seed Germination.
Molecules
2023
37836842
Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile.
Molecules
2023
36614163
Modelling the Transitioning of SARS-CoV-2 nsp3 and nsp4 Lumenal Regions towards a More Stable State on Complex Formation.
Int J Mol Sci
2022
33436497
Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications.
Sci Signal
2021
33684717
Enriching antimicrobial peptides from milk hydrolysates using pectin/alginate food-gels.
Food Chem
2021
34906073
Computational modelling of chromosomally clustering protein domains in bacteria.
BMC Bioinformatics
2021
32218953
Prediction of polyproline II secondary structure propensity in proteins.
R Soc Open Sci
2020
33855271
The future of genomics in Ireland - focus on genomics for health.
HRB Open Res
2020
32864787
Resolving the Interactome of the Human Macrophage Immunometabolism Regulator (MACIR) with Enhanced Membrane Protein Preparation and Affinity Proteomics.
Proteomics
2020
30689642
Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome.
PLoS One
2019
31824707
Implications of kappa-casein evolutionary diversity for the self-assembly and aggregation of casein micelles.
R Soc Open Sci
2019
31824649
An intrinsically disordered proteins community for ELIXIR.
F1000Res
2019
31134568
Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein-Protein Interactions.
Methods Mol Biol
2019
29237089
Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis.
QJM
2018
29927052
Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer.
Mol Oncol
2018
30224653
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Nat Genet
2018
30429575
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Nat Genet
2018
30473799
Peptides derived from cadherin juxtamembrane region inhibit platelet function.
R Soc Open Sci
2018
29638124
Casein Hydrolysate with Glycemic Control Properties: Evidence from Cells, Animal Models, and Humans.
J Agric Food Chem
2018
29760453
Evolutionary instability of CUG-Leu in the genetic code of budding yeasts.
Nat Commun
2018
29258006
Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A<sub>2</sub> formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).
Atherosclerosis
2018
27997202
Peptigram: A Web-Based Application for Peptidomics Data Visualization.
J Proteome Res
2017
28135244
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Nat Genet
2017
28394258
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.
J Clin Invest
2017
28951623
Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Nat Genet
2017
28739976
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
Hypertension
2017
27999994
Functional characterisation of the YIPF protein family in mammalian cells.
Histochem Cell Biol
2017
27085803
ProViz-a web-based visualization tool to investigate the functional and evolutionary features of protein sequences.
Nucleic Acids Res
2016
27587472
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.
J Med Genet
2016
27597145
Impact of genetic variation in the 5-HT transporter and receptor on platelet function in patients with stable CAD taking aspirin.
Thromb Res
2016
27466198
Analysis with the exome array identifies multiple new independent variants in lipid loci.
Hum Mol Genet
2016
25555728
Computational approaches to developing short cyclic peptide modulators of protein-protein interactions.
Methods Mol Biol
2015
26674271
SLiMScape 3.x: a Cytoscape 3 app for discovery of Short Linear Motifs in protein interaction networks.
F1000Res
2015
26039561
Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion.
PLoS One
2015
25875950
Discovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergies.
PLoS Comput Biol
2015
25668361
Virtual screening using combinatorial cyclic peptide libraries reveals protein interfaces readily targetable by cyclic peptides.
J Chem Inf Model
2015
25765234
Genome-wide epistatic expression quantitative trait loci discovery in four human tissues reveals the importance of local chromosomal interactions governing gene expression.
BMC Genomics
2015
24472131
Amino acid enrichment and compositional changes among mammalian milk proteins and the resulting nutritional consequences.
J Dairy Sci
2014
25231912
Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions.
BMC Bioinformatics
2014
25385259
Following the digestion of milk proteins from mother to baby.
J Proteome Res
2014
25350695
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
Nat Commun
2014
25108297
Cadherin juxtamembrane region derived peptides inhibit TGFβ1 induced gene expression.
Bioarchitecture
2014
24793774
In silico approaches to predict the potential of milk protein-derived peptides as dipeptidyl peptidase IV (DPP-IV) inhibitors.
Peptides
2014
24620897
Predicting the important enzymes in human breast milk digestion.
J Agric Food Chem
2014
24478765
Potential of known and short prokaryotic protein motifs as a basis for novel peptide-based antibacterial therapeutics: a computational survey.
Front Microbiol
2014
23568340
SCL-Epred: a generalised de novo eukaryotic protein subcellular localisation predictor.
Amino Acids
2013
24064418
CPPpred: prediction of cell penetrating peptides.
Bioinformatics
2013
23855714
SLiMScape: a protein short linear motif analysis plugin for Cytoscape.
BMC Bioinformatics
2013
24019881
Predicting binding within disordered protein regions to structurally characterised peptide-binding domains.
PLoS One
2013
23929743
Genome-wide analysis of blood pressure variability and ischemic stroke.
Stroke
2013
1 - 50 of 191
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