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Author Details

Amy Hin Yan Tong
University of Toronto
1999
67
42
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37891180N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.Nat Commun2023
34709608A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9.Methods Mol Biol2022
35674384Chromosomal-level reference genome assembly of the North American wolverine (Gulo gulo luscus): a resource for conservation genomics.G3 (Bethesda)2022
36482254A cohesin traffic pattern genetically linked to gene regulation.Nat Struct Mol Biol2022
34018332A method for benchmarking genetic screens reveals a predominant mitochondrial bias.Mol Syst Biol2021
34819670FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.Nature2021
34462321Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene <i>STAG2</i>.Life Sci Alliance2021
32694731Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.Nat Metab2020
32968282Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.Nature2020
30324523Pooled Lentiviral CRISPR-Cas9 Screens for Functional Genomics in Mammalian Cells.Methods Mol Biol2019
31548591High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting.Nat Biomed Eng2019
31545321Pooled CRISPR-Based Genetic Screens in Mammalian Cells.J Vis Exp2019
30970261Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies.Cell Rep2019
29475453Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection.BMC Med Genomics2018
28655737Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.G3 (Bethesda)2017
28087693<i>De Novo</i> Genome and Transcriptome Assembly of the Canadian Beaver (<i>Castor canadensis</i>).G3 (Bethesda)2017
27752041Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes.Sci Rep2016
24572018Mutations enabling displacement of tryptophan by 4-fluorotryptophan as a canonical amino acid of the genetic code.Genome Biol Evol2014
25350659Identification and expression profiling of microRNAs in the brain, liver and gonads of marine medaka (Oryzias melastigma) and in response to hypoxia.PLoS One2014
24947032Targeted next-generation sequencing on Hirschsprung disease: a pilot study exploits DNA pooling.Ann Hum Genet2014
23341963Biased diversity metrics revealed by bacterial 16S pyrotags derived from different primer sets.PLoS One2013
23291631Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.Nat Med2013
22386670Dissemination of pHK01-like incompatibility group IncFII plasmids encoding CTX-M-14 in Escherichia coli from human and animal sources.Vet Microbiol2012
22705009Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma.Gastroenterology2012
22590638Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy.PLoS One2012
22615319Molecular characterization of the 2011 Hong Kong scarlet fever outbreak.J Infect Dis2012
21217751Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection.Nat Methods2011
21743468Increased exonic de novo mutation rate in individuals with schizophrenia.Nat Genet2011
21706171Ammonia-oxidizing archaea and ammonia-oxidizing bacteria in six full-scale wastewater treatment bioreactors.Appl Microbiol Biotechnol2011
21705039Analysis of the bacterial community in a laboratory-scale nitrification reactor and a wastewater treatment plant by 454-pyrosequencing.Water Res2011
21445317Complete sequencing of pNDM-HK encoding NDM-1 carbapenemase from a multidrug-resistant Escherichia coli strain isolated in Hong Kong.PLoS One2011
21489983An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C disease.J Biol Chem2011
21393220Complete sequencing of the FII plasmid pHK01, encoding CTX-M-14, and molecular analysis of its variants among Escherichia coli from Hong Kong.J Antimicrob Chemother2011
20093466The genetic landscape of a cell.Science2010
18286174Ybp2 associates with the central kinetochore of Saccharomyces cerevisiae and mediates proper mitotic progression.PLoS One2008
18604275Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes.PLoS Genet2008
18667535Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae.Mol Biol Cell2008
17460121Sequential and distinct roles of the cadherin domain-containing protein Axl2p in cell polarization in yeast cell cycle.Mol Biol Cell2007
17925448Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z.Proc Natl Acad Sci U S A2007
17681555Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork.Mutat Res2007
17409072Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae.Genetics2007
16118434Synthetic genetic array analysis in Saccharomyces cerevisiae.Methods Mol Biol2006
17077122Genetic and molecular interactions of the Erv41p-Erv46p complex involved in transport between the endoplasmic reticulum and Golgi complex.J Cell Sci2006
16762047Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae.J Biol2006
15766533Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.Cell2005
16172405Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.Proc Natl Acad Sci U S A2005
16327883A network of multi-tasking proteins at the DNA replication fork preserves genome stability.PLoS Genet2005
15982408Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network.J Biol2005
15715908An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae.BMC Genet2005
15077114Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha-acetylation and the integral membrane protein Sys1p.Nat Cell Biol2004
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Collaborators

Charles Boone
University of Toronto
Co-authored papers 35
Jason Moffat
University of Toronto
Co-authored papers 13
Brenda J Andrews
University of Toronto
Co-authored papers 12
Gary D Bader
University of Toronto
Co-authored papers 7
Kevin R Brown
College Street, University of Toronto
Co-authored papers 6
Howard Bussey
McGill University
Co-authored papers 6
Chad L Myers
University of Minnesota - Twin Cities
Co-authored papers 6
Frederick P Roth
University of Toronto
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 4
Huiming Ding
Massachusetts Institute of Technology
Co-authored papers 4
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 4
Michael Costanzo
Co-authored papers 4
Ainslie B Parsons
University of Toronto
Co-authored papers 4
Lan V Zhang
Harvard Medical School
Co-authored papers 4
Guillaume Lesage
Institute of Molecular Biology, University of Zurich
Co-authored papers 4
Renee L Brost
Cubist Pharmaceuticals, Inc.
Co-authored papers 3
Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 3
Zhijian Li
University of Toronto
Co-authored papers 3
Debra S Goldberg
University of Colorado at Boulder
Co-authored papers 3
Stanley Fields
University of Washington
Co-authored papers 3
Sharyl L Wong
Harvard Medical School
Co-authored papers 3
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 3
Christopher W V Hogue
National University of Singapore
Co-authored papers 3
Yiqun Chen
University of Toronto, College Street
Co-authored papers 2
Anne-Marie Sdicu
McGill University
Co-authored papers 2
Patrice Menard
Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark
Co-authored papers 2
Owen Ryan
University of California berkeley
Co-authored papers 2
Gianni Cesareni
University of Rome 'Tor Vergata'
Co-authored papers 2
Timothy R Hughes
University of Toronto
Co-authored papers 2
Christopher G Burd
Yale School of Medicine
Co-authored papers 2
Release 1.2