Author details

Full Name

Christoph Lange

Affiliation

ORCID

Career Start Year

2001

Papers

211

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37533854	Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza.	Front Immunol	2023
35953101	Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma.	Eur Respir J	2023
36255742	FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies.	Hum Mol Genet	2023
37731367	A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data.		2023
36585781	A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.	Brief Bioinform	2023
37372314	Longitudinal Analysis of Contrasts in Gene Expression Data.	Genes (Basel)	2023
36726148	X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study.	Respir Res	2023
35142036	Reply to Neupane etÂ al.: Replication study of AD-associated rare variants.	Alzheimers Dement	2022
35710995	Genome-wide polygenic score to predict chronic kidney disease across ancestries.	Nat Med	2022
35766891	Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data.	Hum Mol Genet	2022
35961980	Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.	Nat Commun	2022
35765100	Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.	Genome Med	2022
35500225	Selection bias when inferring the effect direction in Mendelian randomization.	Genet Epidemiol	2022
35624101	Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.	Nat Commun	2022
35986912	DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents.	J Infect Dis	2022
35544468	Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models.	PLoS One	2022
36383614	A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables.	PLoS Genet	2022
36741030	The Role of Sex in Genetic Association Studies of Depression.	J Psychiatr Brain Sci	2022
36536276	Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.	BMC Bioinformatics	2022
35170805	The influence of unmeasured confounding on the MR Steiger approach.	Genet Epidemiol	2022
33415739	Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus.	Genet Epidemiol	2021
33797837	Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.	Alzheimers Dement	2021
34008876	Caution against examining the role of reverse causality in Mendelian Randomization.	Genet Epidemiol	2021
34159627	Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain.	Genet Epidemiol	2021
33888571	Novel recessive locus for body mass index in childhood asthma.	Thorax	2021
33669563	The Role of SNP Interactions when Determining Independence of Novel Signals in Genetic Association Studies-An Application to <i>ARG1</i> and Bronchodilator Response.	J Pers Med	2021
32929743	locStra: Fast analysis of regional/global stratification in whole-genome sequencingÂ studies.	Genet Epidemiol	2021
33367522	A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests.	Bioinformatics	2021
32855217	A novel locus for exertional dyspnoea in childhood asthma.	Eur Respir J	2021
32946604	An interaction of the 17q12-21 locus with mold exposure in childhood asthma.	Pediatr Allergy Immunol	2021
33173892	Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.	medRxiv	2020
32193444	Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.	Sci Rep	2020
32166765	The effects of misspecification of the mediator and outcome in mediation analysis.	Genet Epidemiol	2020
31713269	A flexible and nearly optimal sequential testing approach to randomized testing: QUICK-STOP.	Genet Epidemiol	2020
32637951	Unsupervised cluster analysis of SARS-CoV-2 genomes indicates that recent (June 2020) cases in Beijing are from a genetic subgroup that consists of mostly European and South(east) Asian samples, of which the latter are the most recent.	bioRxiv	2020
32637949	Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus.	bioRxiv	2020
31429121	Effect of population stratification on SNP-by-environment interaction.	Genetic Epidemiology	2019
30609057	A comparison of popular TDT-generalizations for family-based association analysis.	Genetic Epidemiology	2019
31275357	metaFARVAT: An Efficient Tool for Meta-Analysis of Family-Based, Case-Control, and Population-Based Rare Variant Association Studies.	Front Genet	2019
30908940	Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.	Am J Respir Crit Care Med	2019
29159827	Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm.	Genetic Epidemiology	2018
28968646	PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies.	Biostatistics	2018
30060175	Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.	Hum Mol Genet	2018
29949718	Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.	Am J Respir Cell Mol Biol	2018
27900789	A general approach to testing for pleiotropy with rare and common variants.	Genetic Epidemiology	2017
28345502	Reporting Correct p Values in VEGAS Analyses.	Twin Res Hum Genet	2017
28334167	Identification of genetic outliers due to sub-structure and cryptic relationships.		2017
28318110	On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.	Genet Epidemiol	2017
28044437	Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.	J Cachexia Sarcopenia Muscle	2017
28191685	Gene-based segregation method for identifying rare variants in family-based sequencing studies.	Genet Epidemiol	2017