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Author Details

Jacob P Hoj
Duke University
2014
15
7
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36711936MCB-613 exploits a collateral sensitivity in drug resistant <i>EGFR</i>-mutant non-small cell lung cancer through covalent inhibition of KEAP1.bioRxiv2023
37882674Activation of KrasG12D in Subset of Alveolar Type II Cells Enhances Cellular Plasticity in Lung Adenocarcinoma.Cancer Res Commun2023
37781087ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination.Neurooncol Adv2023
37493631CBF-Beta Mitigates PI3K-Alpha-Specific Inhibitor Killing through PIM1 in PIK3CA-Mutant Gastric Cancer.Mol Cancer Res2023
37040401ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1.Proc Natl Acad Sci U S A2023
36918588Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis.Nat Commun2023
35668193P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.Nat Cancer2022
34706244ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells.Cell Rep2021
33119681Mesenchymal stem cells promote metastasis through activation of an ABL-MMP9 signaling axis in lung cancer cells.PLoS One2020
33318173The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis.Proc Natl Acad Sci U S A2020
31213459The Evolving Modern Management of Brain Metastasis.Clin Cancer Res2019
31825826A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis.Cell Rep2019
29433928Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization.Bioorg Med Chem Lett2018
28780159Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms.Bioorg Med Chem Lett2017
24780819Cellular contractility changes are sufficient to drive epithelial scattering.Exp Cell Res2014
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Collaborators

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Institut Curie, PSL Research University
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Universite de Paris, INSERM, CNRS
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Universite de Paris, Inserm CIC 1427
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Duke University Medical Center
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Comprehensive Cancer Center of Wake Forest Baptist Health, Medical Center Boulevard
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