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Author Details

Gunnar von Heijne
Stockholm University
1973
360
111
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36520514Cotranslational folding of human growth hormone in vitro and in Escherichia coli.FEBS Lett2023
34881571Probing Interplays between Human XBP1u Translational Arrest Peptide and 80S Ribosome.J Chem Theory Comput2022
35994672Cotranslational folding and assembly of the dimeric <i>Escherichia coli</i> inner membrane protein EmrE.Proc Natl Acad Sci U S A2022
34980915SignalP 6.0 predicts all five types of signal peptides using protein language models.Nat Biotechnol2022
35038773Upstream charged and hydrophobic residues impact the timing of membrane insertion of transmembrane helices.FEBS Lett2022
33953328The ribosome modulates folding inside the ribosomal exit tunnel.Commun Biol2021
33554862Residue-by-residue analysis of cotranslational membrane protein integration in vivo.Elife2021
34433673Molten globules lure transmembrane helices away from the membrane.Proc Natl Acad Sci U S A2021
34403461Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.Nucleic Acids Res2021
33989648Cotranslational Translocation and Folding of a Periplasmic Protein Domain in Escherichia coli.J Mol Biol2021
34153216Introduction to the Theme on Membrane Channels.Annu Rev Biochem2021
32513720Cotranslational folding cooperativity of contiguous domains of α-spectrin.Proc Natl Acad Sci U S A2020
31821735Membrane integration and topology of RIFIN and STEVOR proteins of the Plasmodium falciparum parasite.FEBS J2020
31764998The Mgr2 subunit of the TIM23 complex regulates membrane insertion of marginal stop-transfer signals in the mitochondrial inner membrane.FEBS Lett2020
32790204Cotranslational folding of alkaline phosphatase in the periplasm of Escherichia coli.Protein Sci2020
30696770Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase.J Biol Chem2019
31664210Nobel Committee responds to criticism.Nature2019
31246176Structural and mutational analysis of the ribosome-arresting human XBP1u.Elife2019
31501590Dynamic membrane topology in an unassembled membrane protein.Nat Chem Biol2019
31570514Detecting sequence signals in targeting peptides using deep learning.Life Sci Alliance2019
31100385Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.J Mol Biol2019
30778233SignalP 5.0 improves signal peptide predictions using deep neural networks.Nat Biotechnol2019
30738895Force-Profile Analysis of the Cotranslational Folding of HemK and Filamin Domains: Comparison of Biochemical and Biophysical Folding Assays.J Mol Biol2019
31119599A Brief History of Protein Sorting Prediction.Protein J2019
29523692Membrane protein serendipity.J Biol Chem2018
29990469Direct Detection of Membrane-Inserting Fragments Defines the Translocation Pores of a Family of Pathogenic Toxins.J Mol Biol2018
29925266Protein Evolution and Design.Annu Rev Biochem2018
30224455Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome.Proc Natl Acad Sci U S A2018
30366631Forces on Nascent Polypeptides during Membrane Insertion and Translocation via the Sec Translocon.Biophys J2018
30539762Cotranslational Folding of a Pentarepeat β-Helix Protein.J Mol Biol2018
30475203The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding.Elife2018
30413621Folding pathway of an Ig domain is conserved on and off the ribosome.Proc Natl Acad Sci U S A2018
30531789Transmembrane but not soluble helices fold inside the ribosome tunnel.Nat Commun2018
27925654Mutational analysis of protein folding inside the ribosome exit tunnel.FEBS Lett2017
28112730Cotranslational folding of spectrin domains via partially structured states.Nat Struct Mol Biol2017
28409218Transmembrane helices containing a charged arginine are thermodynamically stable.Eur Biophys J2017
28753126Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide.Elife2017
28698365Stable membrane orientations of small dual-topology membrane proteins.Proc Natl Acad Sci U S A2017
28505373Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants.Mol Biol Evol2017
28556777The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling.Elife2017
26906929Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein.J Mol Biol2016
27694387The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel.Biochem J2016
27601675Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids.Proc Natl Acad Sci U S A2016
27620701Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.Biochemistry2016
27487212Global profiling of SRP interaction with nascent polypeptides.Nature2016
27096604Coordinated disassembly of the divisome complex in Escherichia coli.Mol Microbiol2016
26987712Biological insertion of computationally designed short transmembrane segments.Sci Rep2016
26879042Small protein domains fold inside the ribosome exit tunnel.FEBS Lett2016
25162177Forcing the issue: aromatic tuning facilitates stimulus-independent modulation of a two-component signaling circuit.ACS Synth Biol2015
26321634Cotranslational Protein Folding inside the Ribosome Exit Tunnel.Cell Rep2015
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Collaborators

Stephen H White
Co-authored papers 16
S??ren Brunak
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 15
Olof Emanuelsson
KTH Royal Institute of Technology
Co-authored papers 9
Roland Beckmann
University of Munich
Co-authored papers 7
Bengt Persson
Karolinska Institutet
Co-authored papers 6
Mathias Uhl??n
KTH Royal Institute of Technology
Co-authored papers 3
Erik L L Sonnhammer
Stockholm University
Co-authored papers 3
Rita Casadio
Department of Pharmacy and Biotechnology, University of Bologna
Co-authored papers 3
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KTH Royal Institute of Technology
Co-authored papers 2
Lars Juhl Jensen
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 2
Ineke Braakman
Utrecht University
Co-authored papers 1
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University of California los angeles
Co-authored papers 1
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Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Anders Hamsten
Co-authored papers 1
Jenny Ottosson
Bio Pharmaceuticals R&D
Co-authored papers 1
Antoine Danchin
University of Hong Kong
Co-authored papers 1
Cristina Al-Khalili Szigyarto
KTH-Royal Institute of Technology
Co-authored papers 1
David A Liberles
Temple University
Co-authored papers 1
Tove Alm
KTH Royal Institute of Technology
Co-authored papers 1
P??l Stenmark
Stockholm University
Co-authored papers 1
Mary Eileen Dolan
University of Chicago
Co-authored papers 1
Holger Berling
KTH-Royal Institute of Technology
Co-authored papers 1
Fiona Cunningham
European Bioinformatics Institute
Co-authored papers 1
Caroline Kampf
Uppsala University
Co-authored papers 1
Rebecca C Wade
Center for Molecular Biology (ZMBH), Heidelberg University
Co-authored papers 1
Carol V Robinson
University of Oxford
Co-authored papers 1
David Vallenet
Institut Francois Jacob, CNRS, Universite d'Evry, Universite Paris-Saclay
Co-authored papers 1
Anna Asplund
Uppsala University
Co-authored papers 1
Per-Henrik Edqvist
Uppsala University
Co-authored papers 1
David R Nelson
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Release 1.2