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Author Details

Christian Haass
German Center for Neurodegenerative Diseases (DZNE) Munich
1981
419
119
PMIDPaper TitleJournal TitlePublished Year
35950218Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.Cardiovasc Res2023
35950218Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.Cardiovasc Res2023
37562402Distinct molecular profiles of skull bone marrow in health and neurological disorders.Cell2023
37775827A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls.Mol Neurodegener2023
36829182Depletion and activation of microglia impact metabolic connectivity of the mouse brain.J Neuroinflammation2023
36823473Author Correction: Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.Nat Metab2023
37398209A MICROGLIAL ACTIVITY STATE BIOMARKER PANEL DIFFERENTIATES FTD-GRANULIN AND ALZHEIMER'S DISEASE PATIENTS FROM CONTROLS.bioRxiv2023
36635496A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.Nat Neurosci2023
37258678Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.Nature2023
37384248Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased <i>fibronectin</i>, <i>vcam 1</i> and <i>integrin α4/β1</i>.Front Cell Dev Biol2023
36620941sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease.EMBO Mol Med2023
37502831Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions.bioRxiv2023
37495886Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies.Mol Psychiatry2023
36975090APOE and immunity: Research highlights.Alzheimers Dement2023
37562402Distinct molecular profiles of skull bone marrow in health and neurological disorders.Cell2023
37502831Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions.bioRxiv2023
37775827A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls.Mol Neurodegener2023
37495886Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies.Mol Psychiatry2023
37258678Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.Nature2023
37384248Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased <i>fibronectin</i>, <i>vcam 1</i> and <i>integrin α4/β1</i>.Front Cell Dev Biol2023
36975090APOE and immunity: Research highlights.Alzheimers Dement2023
37398209A MICROGLIAL ACTIVITY STATE BIOMARKER PANEL DIFFERENTIATES FTD-GRANULIN AND ALZHEIMER'S DISEASE PATIENTS FROM CONTROLS.bioRxiv2023
36620941sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease.EMBO Mol Med2023
36829182Depletion and activation of microglia impact metabolic connectivity of the mouse brain.J Neuroinflammation2023
36635496A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.Nat Neurosci2023
36823473Author Correction: Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.Nat Metab2023
34259579Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders.Mult Scler2022
35589403Single-Cell Radiotracer Allocation via Immunomagnetic Sorting to Disentangle PET Signals at Cellular Resolution.J Nucl Med2022
35438230Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.EMBO Rep2022
35690868Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.Mol Neurodegener2022
36001676Response to Comment on "Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases".Sci Transl Med2022
35617280Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.PLoS One2022
36327895Microglia states and nomenclature: A field at its crossroads.Neuron2022
35862308If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?PLoS Biol2022
35666874Signatures of glial activity can be detected in the CSF proteome.Proc Natl Acad Sci U S A2022
34016733Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease.J Nucl Med2022
34259579Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders.Mult Scler2022
35019161Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.EMBO J2022
35617280Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.PLoS One2022
35438230Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.EMBO Rep2022
35666874Signatures of glial activity can be detected in the CSF proteome.Proc Natl Acad Sci U S A2022
35690868Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.Mol Neurodegener2022
35862308If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?PLoS Biol2022
35589403Single-Cell Radiotracer Allocation via Immunomagnetic Sorting to Disentangle PET Signals at Cellular Resolution.J Nucl Med2022
36001676Response to Comment on "Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases".Sci Transl Med2022
36327895Microglia states and nomenclature: A field at its crossroads.Neuron2022
35019161Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.EMBO J2022
34016733Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease.J Nucl Med2022
30899092The BDNF<sub>Val66Met</sub> SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.Mol Psychiatry2021
34073557Impact of TSPO Receptor Polymorphism on [<sup>18</sup>F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders.Life (Basel)2021
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Collaborators

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Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 10
Peter St George-Hyslop
Cambridge Institute for Medical Research, University of Cambridge
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John C Morris
Washington University School of Medicine
Co-authored papers 7
Kathryn M Monroe
Denali Therapeutics Inc.
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John Q Trojanowski
University of Pennsylvania
Co-authored papers 6
Cynthia A Lemere
Co-authored papers 5
Oleg Butovsky
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Fargol Mazaheri
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Laura Piccio
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Alison M Goate
Icahn School of Medicine at Mount Sinai
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Michael W Weiner
University of California San Francisco
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Stephen Salloway
Butler Hospital, and Warren Alpert Medical School of Brown University
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Marco Prinz
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Perelman School of Medicine, University of Pennsylvania
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Peter R Schofield
University of New South Wales
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Christian Schultz
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Susanne Krasemann
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Nick C Fox
UK Dementia Research Institute, University College London
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Charlotte Madore
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Eric McDade
Washington University St. Louis
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Bradley T Hyman
Massachusetts General Hospital
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Christian Klose
Institut fur Werkstoffkunde (Materials Science), Leibniz Universitat Hannover
Co-authored papers 2
Li-Huei Tsai
The Picower Institute for Learning and Memory, Massachusetts Institute of Technology
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Tobias Madl
Gottfried Schatz Research Center, Medical University of Graz
Co-authored papers 2
Stephan A M??ller
German Center for Neurodegenerative Diseases, Technical University of Munich
Co-authored papers 2
Scott T Smith
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Lars Lannfelt
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You-Qiang Song
The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University
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Sunita S Shankaran
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Release 1.2