| 34850536 | FGF7-FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas. | Mol Oncol | 2022 |
| 34737188 | DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition. | Cancer Discovery | 2022 |
| 34753775 | HER3 Is an Actionable Target in Advanced Prostate Cancer. | Cancer Res | 2021 |
| 34169282 | Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients. | Neurooncol Adv | 2021 |
| 33900873 | High grade gliomas in young children: The South Thames Neuro-Oncology unit experience and recent advances in molecular biology and targeted therapies. | Pediatric Hematology and Oncology | 2021 |
| 32595135 | Noninvasive MRI Native T<sub>1</sub> Mapping Detects Response to <i>MYCN</i>-targeted Therapies in the Th-<i>MYCN</i> Model of Neuroblastoma. | Cancer Res | 2020 |
| 31786093 | DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study. | Lancet Child Adolesc Health | 2020 |
| 32238360 | Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes. | Cancer Discov | 2020 |
| 31874108 | Genomics of lethal prostate cancer at diagnosis and castration resistance. | J Clin Invest | 2020 |
| 31806540 | Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial. | Lancet Oncol | 2020 |
| 31098401 | ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma. | Commun Biol | 2019 |
| 30615140 | Corrigendum: Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth. | Hum Mol Genet | 2019 |
| 30877107 | MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment. | Cancer Res | 2019 |
| 31543384 | A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations. | Eur J Cancer | 2019 |
| 30885698 | Identification of new Wilms tumour predisposition genes: an exome sequencing study. | | 2019 |
| 29555663 | Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC). | Clin Cancer Res | 2018 |
| 30068710 | SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity. | Clin Cancer Res | 2018 |
| 29973717 | CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. | Nature | 2018 |
| 29967352 | Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells. | Nat Med | 2018 |
| 30382943 | Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer. | J Clin Invest | 2018 |
| 30042009 | Ataxia Telangiectasia Mutated Protein Loss and Benefit From Oxaliplatin-based Chemotherapy in Colorectal Cancer. | Clin Colorectal Cancer | 2018 |
| 30179225 | Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer. | J Clin Invest | 2018 |
| 29348602 | The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion. | Scientific Reports | 2018 |
| 28966033 | Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. | Cancer Cell | 2017 |
| 28553959 | Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation. | Nature Genetics | 2017 |
| 28450425 | Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition. | Cancer Discov | 2017 |
| 28475857 | Mutations in Epigenetic Regulation Genes Are a Major Cause of Overgrowth with Intellectual Disability. | Am J Hum Genet | 2017 |
| 27485037 | OpEx - a validated, automated pipeline optimised for clinical exome sequence analysis. | Scientific Reports | 2016 |
| 28459104 | Accurate clinical detection of exon copy number variants in a targeted NGS panel using DECoN. | Wellcome Open Research | 2016 |
| 26315209 | CSN and CAVA: variant annotation tools for rapid, robust next-generation sequencing analysis in the clinical setting. | Genome Medicine | 2015 |
| 25972378 | Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth. | Hum Mol Genet | 2015 |
| 26834991 | The ICR1000 UK exome series: a resource of gene variation in an outbred population. | F1000Research | 2015 |
| 23098902 | Characterization of Arabidopsis serine:glyoxylate aminotransferase, AGT1, as an asparagine aminotransferase. | Phytochemistry | 2013 |
| 22891909 | More than an education: the hidden curriculum, professional attitudes and career choice. | Medical Education | 2012 |