Author details

Full Name

Xuelian Luo

Affiliation

University of Texas Southwestern Medical Center

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36398861	Discovery of a new class of reversible TEA domain transcription factor inhibitors with a novel binding mode.	Elife	2022
33633399	Cryo-EM structure of the Hippo signaling integrator human STRIPAK.	Nat Struct Mol Biol	2021
32292165	STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism.	Elife	2020
32773040	Cryo-EM structure of VASH1-SVBP bound to microtubules.	Elife	2020
32355745	ADAMTS12 acts as a cancer promoter in colorectal cancer via activating the Wnt/Î²-catenin signaling pathway <i>in vitro</i>.	Ann Transl Med	2020
32259481	Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.	Cell Stem Cell	2020
30565138	Structural and Biochemical Analyses of the Core Components of the Hippo Pathway.	Methods Mol Biol	2019
31235910	Structural basis of tubulin detyrosination by vasohibins.	Nat Struct Mol Biol	2019
30038061	Activation mechanisms of the Hippo kinase signaling cascade.	Biosci Rep	2018
29063833	SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.	Elife	2017
29208896	Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.	Nat Commun	2017
26971492	Structural Basis and IP6 Requirement for Pds5-Dependent Cohesin Dynamics.	Mol Cell	2016
26900866	Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway.	Nat Chem Biol	2016
27027290	Structural basis of cohesin cleavage by separase.	Nature	2016
25505175	The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.	J Biol Chem	2015
26305957	Structure of an intermediate conformer of the spindle checkpoint protein Mad2.	Proc Natl Acad Sci U S A	2015
26592798	Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.	Structure	2015
26108669	Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.	Genes Dev	2015
25156254	Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.	Nature	2014
25308863	Substrate-specific activation of the mitotic kinase Bub1 through intramolecular autophosphorylation and kinetochore targeting.	Structure	2014
23972470	Structural basis for autoactivation of human Mst2 kinase and its regulation by RASSF5.	Structure	2013
22361149	Mitosis: short-circuiting spindle checkpoint signaling.	Curr Biol	2012
22955930	In support of the BMRB.	Nat Struct Mol Biol	2012
23091007	Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.	Proc Natl Acad Sci U S A	2012
22493223	Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting.	Proc Natl Acad Sci U S A	2012
20368466	Structural and functional analysis of the YAP-binding domain of human TEAD2.	Proc Natl Acad Sci U S A	2010
21041666	Phosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition.	Proc Natl Acad Sci U S A	2010
21203923	Snapshots of a hybrid transcription factor in the Hippo pathway.	Protein Cell	2010
18318601	Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer.	PLoS Biol	2008
19000814	Protein metamorphosis: the two-state behavior of Mad2.	Structure	2008
18022368	p31comet blocks Mad2 activation through structural mimicry.	Cell	2007
16885027	Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase.	Mol Cell	2006
16275333	Purification and assay of Mad2: a two-state inhibitor of anaphase-promoting complex/cyclosome.	Methods Enzymol	2005
15170330	T antigen origin-binding domain of simian virus 40: determinants of specific DNA binding.	Biochemistry	2004
15257285	Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint.	EMBO J	2004
15024386	The Mad2 spindle checkpoint protein has two distinct natively folded states.	Nat Struct Mol Biol	2004
11804586	The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.	Mol Cell	2002
10700282	Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.	Nat Struct Biol	2000
9094674	Purification of the simian virus 40 (SV40) T antigen DNA-binding domain and characterization of its interactions with the SV40 origin.	J Virol	1997
8946857	Solution structure of the origin DNA-binding domain of SV40 T-antigen.	Nat Struct Biol	1996
8995843	HCN, a triple-resonance NMR technique for selective observation of histidine and tryptophan side chains in 13C/15N-labeled proteins.	J Magn Reson B	1996

1 - 41 of 41

Ishan Deshpande

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2016

Number of shared co-authors 3

Dennis Goldfarb

Washington University School of Medicine

Career Start Year 2012

Number of shared co-authors 0

Florent Dingli

Institut Curie, PSL Research University

Career Start Year 2011

Number of shared co-authors 0

Bingbing Wan

Shanghai Jiao Tong University

Career Start Year 2007

Number of shared co-authors 1

Lisa M Miller Jenkins

National Cancer Institute, National Institutes of Health

Career Start Year 2005

Number of shared co-authors 1

Xing Guo

Life Sciences Institute, Zhejiang University

Career Start Year 2004

Number of shared co-authors 1

Christopher C Ebmeier

University of Colorado

Career Start Year 2004

Number of shared co-authors 1

Daniel Y L Mao

Lunenfeld-Tanenbaum Research Institute

Career Start Year 2003

Number of shared co-authors 0

Alex Zelter

University of Washington

Career Start Year 2003

Number of shared co-authors 2

Yufeng Tong

University of Windsor

Career Start Year 2002

Number of shared co-authors 0

Shawn S-C Li

University of Western Ontario

Career Start Year 2002

Number of shared co-authors 2

Andrew P VanDemark

University of Pittsburgh

Career Start Year 2000

Number of shared co-authors 0

Owen R Davies

Institute of Cell Biology, University of Edinburgh

Career Start Year 2000

Number of shared co-authors 0

Rachel Toth

University of Dundee

Career Start Year 1999

Number of shared co-authors 4

Ning Zheng

University of Washington

Career Start Year 1996

Number of shared co-authors 2

James A Wohlschlegel

David Geffen School of Medicine, University of California Los Angeles

Career Start Year 1996

Number of shared co-authors 0

Damarys Loew

Institut Curie, PSL Research University

Career Start Year 1996

Number of shared co-authors 0

Matthias Gstaiger

Institute of Molecular Systems Biology, ETH Zurich

Career Start Year 1994

Number of shared co-authors 0

Jean-Karim H??rich??

University of California san francisco

Career Start Year 1994

Number of shared co-authors 0

Anne-Claude Gingras

Lunenfeld-Tanenbaum Research Institute

Career Start Year 1994

Number of shared co-authors 1

Yunyu Shi

University of Science & Technology of China

Career Start Year 1993

Number of shared co-authors 2

Nikola P Pavletich

Memorial Sloan Kettering Cancer Center

Career Start Year 1991

Number of shared co-authors 2

Sirano Dhe-Paganon

Dana-Farber Cancer Institute

Career Start Year 1989

Number of shared co-authors 9

Peter K Jackson

Stanford University School of Medicine, Center for Clinical Sciences Research

Career Start Year 1989

Number of shared co-authors 0

Cheryl H Arrowsmith

University of Toronto

Career Start Year 1989

Number of shared co-authors 16

Ronen Marmorstein

Perelman School of Medicine, University of Pennsylvania

Career Start Year 1987

Number of shared co-authors 0

Hediye Erdjument-Bromage

Neuroscience Institute, NYU Grossman School of Medicine

Career Start Year 1984

Number of shared co-authors 0

Stefan Knapp

Institute of Pharmaceutical Chemistry, Goethe University

Career Start Year 1983

Number of shared co-authors 6

John Kuriyan

University of California berkeley

Career Start Year 1982

Number of shared co-authors 4

J. Wade Harper

Harvard Medical School

Career Start Year 1981

Number of shared co-authors 1

row(s) 1 - 30 of 30

Diana R Tomchick

University of Texas Southwestern Medical Center

Co-authored papers 10

Josep Rizo

University of Texas Southwestern Medical Center

Co-authored papers 6

Chad A Brautigam

UT Southwestern Medical Center

Co-authored papers 4

Ulrich L G??nther

Institute of Chemistry and Metabolomics, University of Lubeck

Co-authored papers 2

Timothy B Sackton

Harvard University

Co-authored papers 1

Michael R Gryk

University of Illinois

Co-authored papers 1

Walter J Chazin

and Center for Structural Biology, Vanderbilt University

Co-authored papers 1

Bernd Reif

Technische Universitat Munchen (TUM)

Co-authored papers 1

Matthew P Crump

University of Bristol

Co-authored papers 1

Alexander P Golovanov

The University of Manchester

Co-authored papers 1

David A Case

Rutgers University

Co-authored papers 1

Oliver F Lange

Center for Integrated Protein Science, Technische Universitat Munchen

Co-authored papers 1

Gordon C K Roberts

Leicester Institute of Structural and Chemical Biology, University of Leicester

Co-authored papers 1

Mike P Williamson

The University of Sheffield

Co-authored papers 1

Lu-Yun Lian

Institute of Systems, The University of Liverpool

Co-authored papers 1

Igor L Barsukov

Institute of Integrative Biology, University of Liverpool

Co-authored papers 1

David E Shaw

Columbia University

Co-authored papers 1

Ad Bax

National Institutes of Health

Co-authored papers 1

Patrick C A van der Wel

Zernike Institute for Advanced Materials, University of Groningen

Co-authored papers 1

David Middleton

Co-authored papers 1

Ioannis Vakonakis

University of Oxford

Co-authored papers 1

Thomas A Frenkiel

The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute

Co-authored papers 1

Ernest D Laue

University of Cambridge

Co-authored papers 1

Gordon S Rule

Carnegie Mellon University

Co-authored papers 1

Stephen Matthews

Imperial College London

Co-authored papers 1

Chien Ho

Carnegie Mellon University

Co-authored papers 1

Toshimichi Fujiwara

Institute for Protein Research, Osaka University

Co-authored papers 1

Pei Tang

Sichuan University

Co-authored papers 1

Joern Werner

Co-authored papers 1

Paul C Driscoll

The Francis Crick Institute

Co-authored papers 1

1 - 30

Author Details

Column Actions

Recommended Authors

Collaborators