Author details

Full Name

Shikhar Mehrotra

Affiliation

ORCID

Career Start Year

1999

Papers

106

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37000627	Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.	Cell Rep	2023
37745348	Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer.		2023
37828860	Fatty Acids Invigorate Tumor-Resident Memory T Cells.		2023
37648102	Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma.		2023
37321450	A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression.		2023
34714588	Modulating donor mitochondrial fusion/fission delivers immunoprotective effects in cardiac transplantation.	Am J Transplant	2022
35513703	Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway.	Leukemia	2022
36034228	Quantitative increase in T regulatory cells enhances bone remodeling in .	iScience	2022
35648389	Intracellular Acetyl CoA Potentiates the Therapeutic Efficacy of Antitumor CD8+ T Cells.	Cancer Research	2022
35817212	HuR as a molecular target for cancer therapeutics and immune-related disorders.	Advanced Drug Delivery Reviews	2022
35747323	Direct NP- A cost-effective extraction-free RT-qPCR based test for SARS-CoV-2.	Heliyon	2022
36209107	The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases.	Journal of Neuroinflammation	2022
36071219	S1P/S1PR1 signaling differentially regulates the allogeneic response of CD4 and CD8 T cells by modulating mitochondrial fission.	Cellular and Molecular Immunology	2022
35404405	Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function.	Cancer Res	2022
36476873	Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis.		2022
34927354	Eosinophils and melanoma: Implications for immunotherapy.	Pigment Cell and Melanoma Research	2022
35203357	New Developments in T Cell Immunometabolism and Implications for Cancer Immunotherapy.	Cells	2022
33972936	Impaired T-cell and antibody immunity after COVID-19 infection in chronically immunosuppressed transplant recipients.	bioRxiv	2021
33969281	Comparative analysis of antibodies to SARS-CoV-2 between asymptomatic and convalescent patients.	iScience	2021
34070758	Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma.	Cancers	2021
33628191	Reduction of Neuroinflammation by Î´-Opioids Via STAT3-Dependent Pathway in Chronic Glaucoma Model.	Frontiers in Pharmacology	2021
34224636	Hematopoietic stem cell-derived functional osteoblasts exhibit therapeutic efficacy in a murine model of osteogenesis imperfecta.	Stem Cells	2021
33951438	Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor TÂ cell response.	Cell Reports	2021
34244584	Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients.	Scientific Reports	2021
32937189	Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma.	Free Radical Biology and Medicine	2020
32061543	CD38: Modulating Histone Methyltransferase EZH2 Activity in SLE.	Trends in Immunology	2020
32294407	The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.	Immunity	2020
32709019	CD38: T Cell Immuno-Metabolic Modulator.	Cells	2020
32915982	Histone Deacetylases Regulation by Î´-Opioids in Human Optic Nerve Head Astrocytes.	Investigative Ophthalmology and Visual Science	2020
33335528	Antigen Specificity Enhances Disease Control by Tregs in Vitiligo.	Frontiers in Immunology	2020
32894753	Evaluation of Orthogonal Testing Algorithm for Detection of SARS-CoV-2 IgG Antibodies.	Clin Chem	2020
33263714	Changes in Class I and IIb HDACs by Î´-Opioid in Chronic Rat Glaucoma Model.	Investigative Ophthalmology and Visual Science	2020
32937437	Identification of human CD4<sup>+</sup> T cell populations with distinct antitumor activity.	Sci Adv	2020
31045571	Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.	J Clin Invest	2019
31645480	CD38-NAD-Sirt1 axis in T cell immunotherapy.	Aging	2019
30514750	Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice.	Blood	2019
30327305	Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response.	Clinical Cancer Research	2019
31515721	Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo.	Annals of Surgical Oncology	2019
30971427	Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells.	J Biol Chem	2019
31417079	Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.	Nature Communications	2019
30680957	Mesenchymal Stem Cells from Chronic Pancreatitis Patients Show Comparable Potency Compared to Cells from Healthy Donors.	Stem cells translational medicine	2019
31412253	Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity.	Cell Reports	2019
30894532	ER stress-induced mediator C/EBP homologous protein thwarts effector TÂ cell activity in tumors through T-bet repression.	Nature Communications	2019
29538260	Impact of Mitochondrial Permeability on Endothelial Cell Immunogenicity in Transplantation.	Transplantation	2018
30140266	CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies.	Frontiers in Immunology	2018
29443657	IL-2 and Beyond in Cancer Immunotherapy.	Journal of Interferon and Cytokine Research	2018
29129787	CD38-NAD<sup>+</sup>Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.	Cell Metab	2018
29374060	-Glutathionylation of estrogen receptor Î± affects dendritic cell function.	Journal of Biological Chemistry	2018
29636345	Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8<sup>+</sup> T Cells.	Cancer Res	2018
29795229	Hematopoietic Stem Cells as a Novel Source of Dental Tissue Cells.	Scientific Reports	2018