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Author Details

Alexander N Freiberg
University of Texas Medical Branch
2008
107
38
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36379378The prophylactic and therapeutic efficacy of the broadly active antiviral ribonucleoside N<sup>4</sup>-Hydroxycytidine (EIDD-1931) in a mouse model of lethal Ebola virus infection.Antiviral Res2023
38005825<i>Pteropus vampyrus</i> TRIM40 Is an Interferon-Stimulated Gene That Antagonizes RIG-I-like Receptors.Viruses2023
37515275The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection.Viruses2023
37509430Hydrogen Sulfide Ameliorates SARS-CoV-2-Associated Lung Endothelial Barrier Disruption.Biomedicines2023
37610585Syrian Golden Hamster Model for Nipah Virus Infection.Methods Mol Biol2023
37610580In Vivo Imaging of Nipah Virus Infection in Small Animal Rodent Models.Methods Mol Biol2023
37503276Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities.bioRxiv2023
36851495Differences in Genetic Diversity of Mammalian Tick-Borne Flaviviruses.Viruses2023
36869692Nipah Virus Bangladesh Infection Elicits Organ-Specific Innate and Inflammatory Responses in the Marmoset Model.J Infect Dis2023
36731656Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals.Antiviral Res2023
35263596The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.Cell Rep2022
35533195Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.PLoS Pathog2022
36131104Evaluations of rationally designed rift valley fever vaccine candidate RVax-1 in mosquito and rodent models.NPJ Vaccines2022
36297275Powassan Virus Induces Structural Changes in Human Neuronal Cells In Vitro and Murine Neurons In Vivo.Pathogens2022
33436903Targeted disruption of pi-pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity.Sci Rep2021
33657175Inhibition of innate immune response ameliorates Zika virus-induced neurogenesis deficit in human neural stem cells.PLoS Negl Trop Dis2021
33494095Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.Nature2021
33782133Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition.Proc Natl Acad Sci U S A2021
35056541Tilorone-Dihydrochloride Protects against Rift Valley Fever Virus Infection and Disease in the Mouse Model.Microorganisms2021
34384825Polyphenylene carboxymethylene (PPCM) microbicide repurposed as antiviral against SARS-CoV-2. Proof of concept in primary human undifferentiated epithelial cells.Antiviral Res2021
34516560Rift Valley fever virus 78kDa envelope protein attenuates virus replication in macrophage-derived cell lines and viral virulence in mice.PLoS Negl Trop Dis2021
34632460Recent advances in combating Nipah virus.Fac Rev2021
34131306Author Correction: Spike mutation D614G alters SARS-CoV-2 fitness.Nature2021
33965007Discovery of a novel highly potent broad-spectrum heterocyclic chemical series of arenavirus cell entry inhibitors.Bioorg Med Chem Lett2021
34372594STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV).Viruses2021
33372854SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.Emerg Microbes Infect2021
33106671Spike mutation D614G alters SARS-CoV-2 fitness.Nature2021
32550996Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.ACS Med Chem Lett2020
31694946VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection.J Virol2020
31940478Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism.Cell Rep2020
32682926Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig.Antiviral Res2020
32935091Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.Res Sq2020
32908978Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.bioRxiv2020
32869021Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.bioRxiv2020
30717492Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir.Viruses2019
31351092Polyphenylene carboxymethylene (PPCM) in vitro antiviral efficacy against Ebola virus in the context of a sexually transmitted infection.Antiviral Res2019
31462558Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity.J Virol2019
31307979Repurposing Quinacrine against Ebola Virus Infection <i>In Vivo</i>.Antimicrob Agents Chemother2019
31537423SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors.Bioorg Med Chem Lett2019
30985897Henipavirus infection of the central nervous system.Pathog Dis2019
29133569Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.Antimicrob Agents Chemother2018
30192975Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters.J Infect Dis2018
30135121Phosphorylated VP30 of Marburg Virus Is a Repressor of TranscriptionJ Virol2018
30190498Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing.Sci Rep2018
29912426Experimental Infection of Syrian Hamsters With Aerosolized Nipah Virus.J Infect Dis2018
30459418A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice.Sci Rep2018
30442185Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines.J Neuroinflammation2018
29765101Favipiravir (T-705) protects against Nipah virus infection in the hamster model.Sci Rep2018
28679761The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.J Virol2017
28106111Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses.Sci Rep2017
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