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Author Details

Krushna C Patra
Harvard Medical School
2009
20
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36692000Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms.Elife2023
35173161A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis.Nat Commun2022
33815677BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis.World J Hepatol2021
32273287REDD1 loss reprograms lipid metabolism to drive progression of <i>RAS</i> mutant tumors.Genes Dev2020
30612899AMPK-Mediated Lysosome Biogenesis in Lung Cancer Growth.Cell Metab2019
31386860EGFR Pathway Links Amino Acid Levels and Induction of Macropinocytosis.Dev Cell2019
31109923TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma.Cancer Discov2019
29687779Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation.Elife2018
29946147Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin.Nat Commun2018
29920272A Cell Size Theory of Aging.Dev Cell2018
29941929Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.Nat Cell Biol2018
29871934<i>Kras</i> and <i>Tp53</i> Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.Cancer Res2018
29386513Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin.Nat Commun2018
28383565Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm.Clin Transl Gastroenterol2017
26190111Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration.Cell Rep2015
25037503The pentose phosphate pathway and cancer.Trends Biochem Sci2014
23610444DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer.Cancer Res2013
24196563Hexokinase 2 as oncotarget.Oncotarget2013
23911236Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.Cancer Cell2013
19620286mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.Mol Cell Biol2009
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Collaborators

Nabeel Bardeesy
Massachusetts General Hospital
Co-authored papers 9
Phuong Vu
Harvard Medical School
Co-authored papers 2
Robert B Robey
Geisel School of Medicine at Dartmouth and US Department of Veterans Affairs
Co-authored papers 2
Maciek R Antoniewicz
Massachusetts Institute of Technology
Co-authored papers 2
Daniel K Nomura
University of California berkeley
Co-authored papers 1
Yeonjoo C Hwang
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
John D Scott
University of Washington
Co-authored papers 1
Donald Long
College of Veterinary Medicine, Cornell University
Co-authored papers 1
Raymond S Yeung
University of Washington
Co-authored papers 1
Jochen K Lennerz
Massachusetts General Hospital/Harvard Medical School
Co-authored papers 1
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 1
Cyril H Benes
Co-authored papers 1
Matthew N McCall
Co-authored papers 1
John D Gordan
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Rebecca R B Wolber
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Markku Laakso
Co-authored papers 1
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 1
Clary B Clish
Broad Institute of MIT and Harvard
Co-authored papers 1
Anthony J Iafrate
Massachusetts General Hospital
Co-authored papers 1
Heidi L Kenerson
University of Washington
Co-authored papers 1
Kimberly J Riehle
University of Washington
Co-authored papers 1
Abhishek K Jha
Elucidata Corporation
Co-authored papers 1
Wilhelm Haas
Co-authored papers 1
Samantha Maisel
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Huat Chye Lim
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Bryan C Pascual
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Rigney E Turnham
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Mehdi Bouhaddou
J. David Gladstone Institutes
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Danielle L Swaney
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Release 1.2