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Author Details
Full Name
Melanie Spears
Affiliation
Ontario Institute for Cancer Research
ORCID
Career Start Year
2008
Papers
18
H Index
10
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
31322299
Benchmarking to the Gold Standard: Hyaluronan-Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture.
Adv Mater
2019
35100692
Identification of Distinct Prognostic Groups: Implications for Patient Selection to Targeted Therapies Among Anti-Endocrine Therapy-Resistant Early Breast Cancers.
JCO Precis Oncol
2019
29618387
Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer.
J Ovarian Res
2018
28659176
ISOWN: accurate somatic mutation identification in the absence of normal tissue controls.
Genome Med
2017
27056899
A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial.
Oncotarget
2016
26852132
Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer.
Breast Cancer Res
2016
26372731
A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials.
Oncotarget
2015
24402423
Validated or not validated? That is the question.
J Natl Cancer Inst
2014
25312014
Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance.
BMC Cancer
2014
23152120
Authors' reply.
J Pathol
2013
21390497
The p160 ER co-regulators predict outcome in ER negative breast cancer.
Breast Cancer Res Treat
2012
22562124
Expression of activated type I receptor tyrosine kinases in early breast cancer.
Breast Cancer Res Treat
2012
22430898
Proximity ligation assays for isoform-specific Akt activation in breast cancer identify activated Akt1 as a driver of progression.
J Pathol
2012
21638049
In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer.
Breast Cancer Res Treat
2012
20700126
In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues.
Br J Cancer
2010
19456271
The potential role of estrogen receptors and the SRC family as targets for the treatment of breast cancer.
Expert Opin Ther Targets
2009
19925033
Human epidermal growth factor receptor dimerization analysis in breast cancer diagnosis: potential for improving testing accuracy and treatment selection.
Mol Diagn Ther
2009
20477393
Type I receptor tyrosine kinases as predictive or prognostic markers in early breast cancer.
Biomark Med
2008
1 - 18 of 18
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