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Author Details

Susan A Burchill
Leeds Institute of Medical Research, St. James's University Hospital
1986
97
36
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36765727Exploiting the Stemness and Chemoresistance Transcriptome of Ewing Sarcoma to Identify Candidate Therapeutic Targets and Drug-Repurposing Candidates.Cancers (Basel)2023
36651715Reply to: Comment on: Membrane-type 1 matrix metalloproteinase as predictor of survival and candidate therapeutic target in Ewing sarcoma.Pediatr Blood Cancer2023
36106829Membrane-type 1 matrix metalloproteinase as predictor of survival and candidate therapeutic target in Ewing sarcoma.Pediatr Blood Cancer2022
34050156Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.Nat Commun2021
34403115RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma.Cell Oncol (Dordr)2021
31767563Detection of Circulating and Disseminated Neuroblastoma Cells Using the ImageStream Flow Cytometer for Use as Predictive and Pharmacodynamic Biomarkers.Clin Cancer Res2020
30545920Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma.Cancer Res2019
31575060Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study.Cancers (Basel)2019
30910588ABCG1 and Pgp identify drug resistant, self-renewing osteosarcoma cells.Cancer Lett2019
29603574Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis.Pediatr Blood Cancer2018
29860064Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer.Gene2018
27984660Recommendations for the standardization of bone marrow disease assessment and reporting in children with neuroblastoma on behalf of the International Neuroblastoma Response Criteria Bone Marrow Working Group.Cancer2017
28471719Revisions to the International Neuroblastoma Response Criteria: A Consensus Statement From the National Cancer Institute Clinical Trials Planning Meeting.J Clin Oncol2017
26722004Localization of MRP-1 to the outer mitochondrial membrane by the chaperone protein HSP90β.FASEB J2016
28856217PCR-based amplification of circulating RNAs as prognostic and predictive biomarkers - Focus on neuroblastoma.Pract Lab Med2016
24590653Neuroblastoma mRNAs predict outcome in children with stage 4 neuroblastoma: a European HR-NBL1/SIOPEN study.J Clin Oncol2014
25157404Proliferation index: a continuous model to predict prognosis in patients with tumours of the Ewing's sarcoma family.PLoS One2014
23799853Membrane expression of MRP-1, but not MRP-1 splicing or Pgp expression, predicts survival in patients with ESFT.Br J Cancer2013
22074795Identification of reference microRNAs and suitability of archived hemopoietic samples for robust microRNA expression profiling.Anal Biochem2012
22662320The first European interdisciplinary ewing sarcoma research summit.Front Oncol2012
22353810Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria.Br J Cancer2012
21342042Oxidative stress and therapeutic opportunities: focus on the Ewing's sarcoma family of tumors.Expert Rev Anticancer Ther2011
22174837Heterogeneous role of the glutathione antioxidant system in modulating the response of ESFT to fenretinide in normoxia and hypoxia.PLoS One2011
20308673Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.J Clin Oncol2010
20877355Fenretinide-dependent upregulation of death receptors through ASK1 and p38α enhances death receptor ligand-induced cell death in Ewing's sarcoma family of tumours.Br J Cancer2010
19264125The promise of telomere length, telomerase activity and its regulation in the translocation-dependent cancer ESFT; clinical challenges and utility.Biochim Biophys Acta2009
19665431p38(MAPK): stress responses from molecular mechanisms to therapeutics.Trends Mol Med2009
19401690Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force.Br J Cancer2009
19136249Preclinical evaluation of vascular-disrupting agents in Ewing's sarcoma family of tumours.Eur J Cancer2009
17700534The sensitivity of the Ewing's sarcoma family of tumours to fenretinide-induced cell death is increased by EWS-Fli1-dependent modulation of p38(MAPK) activity.Oncogene2008
18925858Molecular abnormalities in Ewing's sarcoma.Expert Rev Anticancer Ther2008
18471963BAY 11-7082 induces cell death through NF-kappaB-independent mechanisms in the Ewing's sarcoma family of tumours.Cancer Lett2008
18702176Minimal disease monitoring by QRT-PCR: guidelines for identification and systematic validation of molecular markers prior to evaluation in prospective clinical trials.J Pathol2008
18656345Manipulation of oxidative stress to induce cell death in Ewing's sarcoma family of tumours.Eur J Cancer2008
18064647Ploidy and karyotype complexity are powerful prognostic indicators in the Ewing's sarcoma family of tumors: a study by the United Kingdom Cancer Cytogenetics and the Children's Cancer and Leukaemia Group.Genes Chromosomes Cancer2008
17023157Standardisation of operating procedures for the detection of minimal disease by QRT-PCR in children with neuroblastoma: quality assurance on behalf of SIOPEN-R-NET.Eur J Cancer2007
17533400Chromosome 9p21 gene copy number and prognostic significance of p16 in ESFT.Br J Cancer2007
17533364Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data.Oncogene2007
16563089What do, can and should we learn from models to evaluate potential anticancer agents?Future Oncol2006
16860137The hollow fiber assay for drug responsiveness in the Ewing's sarcoma family of tumors.J Pediatr2006
15788688Vascular endothelial growth factor: a therapeutic target for tumors of the Ewing's sarcoma family.Clin Cancer Res2005
15951104Detecting minimal residual disease in neuroblastoma patients-the present state of the art.Cancer Lett2005
15837770p38MAPK-Dependent sensitivity of Ewing's sarcoma family of tumors to fenretinide-induced cell death.Clin Cancer Res2005
15540115Efficient infection and persistence of a herpesvirus saimiri-based gene delivery vector into human tumor xenografts and multicellular spheroid cultures.Cancer Gene Ther2005
14693828Micrometastases in neuroblastoma: are they clinically important?J Clin Pathol2004
15569981The use of real-time reverse transcription-PCR for prostate-specific antigen mRNA to discriminate between blood samples from healthy volunteers and from patients with metastatic prostate cancer.Clin Cancer Res2004
15310753Basic fibroblast growth factor-induced cell death is effected through sustained activation of p38MAPK and up-regulation of the death receptor p75NTR.J Biol Chem2004
14734444A systematic review of molecular and biological tumor markers in neuroblastoma.Clin Cancer Res2004
12504654A systematic review of molecular and biological markers in tumours of the Ewing's sarcoma family.Eur J Cancer2003
14520460FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells.Br J Cancer2003
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Collaborators

Peter J Selby
College of Agriculture and Life Sciences, Cornell University
Co-authored papers 15
Ruth Ladenstein
Children's Cancer Research Institute
Co-authored papers 6
Gudrun Schleiermacher
Institut Curie
Co-authored papers 3
Uta Dirksen
University Hospital Essen, West German Cancer Center
Co-authored papers 3
Peter F Ambros
Children's Cancer Research Institute, Medical University of Vienna
Co-authored papers 3
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 3
Susan L Cohn
Co-authored papers 2
Heinrich Kovar
St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 2
Michelle Haber
School of Clinical Medicine
Co-authored papers 2
Ga??lle Pierron
Institut Curie Hospital
Co-authored papers 2
Markus Metzler
University Hospital Erlangen
Co-authored papers 2
Frank Berthold
Co-authored papers 2
Sandra J Strauss
University College London, Cancer Institute
Co-authored papers 1
Manuela Krumbholz
University Hospital Erlangen
Co-authored papers 1
Dominic J McMullan
Birmingham Women's and Children's NHS Foundation Trust
Co-authored papers 1
Katia Scotlandi
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 1
Andrew J K Williamson
Co-authored papers 1
Stefan Burdach
Technische Universitat Munchen
Co-authored papers 1
Christiane Schaefer
University Hospital Essen, West German Cancer Center
Co-authored papers 1
Eleni M Tomazou
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 1
Udo Kontny
Co-authored papers 1
Didier Surdez
Balgrist University Hospital, University of Zurich (UZH)
Co-authored papers 1
Beat W Sch??fer
Department of Oncology and Children's Research Center, University Children's Hospital
Co-authored papers 1
Bekir Erg??ner
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 1
Michael Dworzak
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 1
Claudia Rossig
University Children's Hospital Muenster
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Mathieu Chicard
INSERM U830 Cancer, Institut Curie Research Center, PSL Research University
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Release 1.2