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Author Details

Joel D Ernst
University of California san francisco
1986
130
52
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36711855High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against <i>M. tuberculosis</i> antigen.bioRxiv2024
36604539Finding antigens for TB vaccines: the good, the bad and the useless.Nat Med2023
37014917Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania.PLoS Pathog2023
37398178Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.Res Sq2023
36920308Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis.J Exp Med2023
36877083Circularization of <i>rv0678</i> for Genotypic Bedaquiline Resistance Testing of Mycobacterium tuberculosis.Microbiol Spectr2023
36711606<i>Mycobacterium tuberculosis</i> resides in lysosome-poor monocyte-derived lung cells during chronic infection.bioRxiv2023
36040958Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients.PLoS One2022
35695454Bacterial Strain-Dependent Dissociation of Cell Recruitment and Cell-to-Cell Spread in Early M. tuberculosis Infection.mBio2022
35552657Mycobacterium tuberculosis antigen-specific T-cell responses in smear-negative pulmonary tuberculosis patients.Clin Exp Immunol2022
36046626High-resolution imaging of protein secretion at the single-cell level using plasmon-enhanced FluoroDOT assay.Cell Rep Methods2022
33074856Schistosoma mansoni Infection Is Associated With a Higher Probability of Tuberculosis Disease in HIV-Infected Adults in Kenya.J Acquir Immune Defic Syndr2021
34852237A defective viral genome strategy elicits broad protective immunity against respiratory viruses.Cell2021
34851691Repeated <i>Plasmodium falciparum</i> infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire.Sci Transl Med2021
34031617Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.Nat Immunol2021
32369456Tryptophan catabolism reflects disease activity in human tuberculosis.JCI Insight2020
31647877Isoniazid and Rifapentine Treatment Eradicates Persistent <i>Mycobacterium tuberculosis</i> in Macaques.Am J Respir Crit Care Med2020
32855547Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.Nat Biotechnol2020
31015327Dynamics of Mycobacterium tuberculosis Ag85B Revealed by a Sensitive Enzyme-Linked Immunosorbent Assay.mBio2019
31527907Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil.PLoS Negl Trop Dis2019
29262261Float Like Bacilli, STING Like a B: Type I Interferons in Tuberculosis.Am J Respir Crit Care Med2018
30001523Mechanisms of M. tuberculosis Immune Evasion as Challenges to TB Vaccine Design.Cell Host Microbe2018
30365557Mononuclear cell dynamics in M. tuberculosis infection provide opportunities for therapeutic intervention.PLoS Pathog2018
29548008Limited Antimycobacterial Efficacy of Epitope Peptide Administration Despite Enhanced Antigen-Specific CD4 T-Cell Activation.J Infect Dis2018
29540577A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human <i>Mycobacterium tuberculosis</i> Infection.J Immunol2018
28930653Fishing for Answers in Human Mycobacterial Infections.Immunity2017
28315719Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 100 Luo infants from the Boro area of Nyanza Province, Kenya.Hum Immunol2017
28476627"The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" - Meeting report.Vaccine2017
29116635Antigenic Variation and Immune Escape in the MTBC.Adv Exp Med Biol2017
26764596Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis.Cell Host Microbe2016
26573837Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo.J Immunol2016
27973588Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity.PLoS Pathog2016
27918526Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4<sup>+</sup> T-cell activation.Nat Microbiol2016
27803172Type I Interferon is Pathogenic During Chronic Mycobacterium africanum Infection.J Infect Dis2016
27599327The Challenge of Latent TB Infection.JAMA2016
27500737The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent.PLoS Pathog2016
27409590A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.PLoS Pathog2016
26024162Combined Measurement of the Higgs Boson Mass in pp Collisions at sqrt[s]=7 and 8 TeV with the ATLAS and CMS Experiments.Phys Rev Lett2015
26650245Correction: LprG-Mediated Surface Expression of Lipoarabinomannan Is Essential for Virulence of Mycobacterium tuberculosis.PLoS Pathog2015
26607161M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens.Cell Host Microbe2015
25910243In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection.Chem Biol2015
26018190Impaired M. tuberculosis Antigen-Specific IFN-γ Response without IL-17 Enhancement in Patients with Severe Cavitary Pulmonary Tuberculosis.PLoS One2015
25938788STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection.J Clin Invest2015
24425732Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition.mBio2014
25211768Impact of in vitro evolution on antigenic diversity of Mycobacterium bovis bacillus Calmette-Guerin (BCG).Vaccine2014
25319335Beyond macrophages: the diversity of mononuclear cells in tuberculosis.Immunol Rev2014
24922576Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4 T cell priming.Cell Host Microbe2014
23418602Induction of CCL8/MCP-2 by mycobacteria through the activation of TLR2/PI3K/Akt signaling pathway.PLoS One2013
23817429Cutting edge: Direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo.J Immunol2013
23951341Equivalent T cell epitope promiscuity in ecologically diverse human pathogens.PLoS One2013
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Co-authored papers 7
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Co-authored papers 4
Oregon Health and Science University
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
University of Washington School of Medicine
Co-authored papers 2
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Co-authored papers 2
Center for Gene Regulation in Health and Disease, Cleveland State University
Co-authored papers 1
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Yale University School of Medicine
Co-authored papers 1
University of California san francisco
Co-authored papers 1
San Francisco General Hospital, University of California
Co-authored papers 1
Co-authored papers 1
Washington University School of Medicine
Co-authored papers 1
Lancaster University
Co-authored papers 1
University of Utah
Co-authored papers 1
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Clinical Biomarkers Laboratory, Emory University
Co-authored papers 1
Massachusetts General Hospital/Harvard Medical School
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University of California san francisco
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Massachusetts General Hospital
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