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Author Details

Philipp W Messer
University of Otago
2005
64
36
PMIDPaper TitleJournal TitlePublished Year
38009398A framework for identifying fertility gene targets for mammalian pest control.Mol Ecol Resour2024
37398071A framework for identifying fertility gene targets for mammalian pest control.bioRxiv2023
37840022Incorporating ecology into gene drive modelling.Ecol Lett2023
37464886Evolution under a model of functionally buffered deleterious mutations can lead to positive selection in protein-coding genes.Evolution2023
37130229SLiM 4: Multispecies Eco-Evolutionary Modeling.Am Nat2023
35137024Predicting the genomic resolution of bulk segregant analysis.G3 (Bethesda)2022
35606745Experimental demonstration of tethered gene drive systems for confined population modification or suppression.BMC Biol2022
35394026A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles.G3 (Bethesda)2022
36239372<i>Anopheles</i> homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure.Elife2022
36264807Deep cis-regulatory homology of the butterfly wing pattern ground plan.Science2022
33404162Suppression gene drive in continuous space can result in unstable persistence of both drive and wild-type alleles.Mol Ecol2021
33635910Detection of hard and soft selective sweeps from Drosophila melanogaster population genomic data.PLoS Genet2021
34965253Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework.PLoS Comput Biol2021
32164660Performance analysis of novel toxin-antidote CRISPR gene drive systems.BMC Biol2020
33897820Design and analysis of CRISPR-based underdominance toxin-antidote gene drives.Evol Appl2020
33335055Core commitments for field trials of gene drive organisms.Science2020
32573438A community-maintained standard library of population genetic models.Elife2020
32646912The Effects of Quantitative Trait Architecture on Detection Power in Short-Term Artificial Selection Experiments.G3 (Bethesda)2020
32929034A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population.Proc Natl Acad Sci U S A2020
32181354Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs.Sci Adv2020
32109227A toxin-antidote CRISPR gene drive system for regional population modification.Nat Commun2020
32142612Population Dynamics of Underdominance Gene Drive Systems in Continuous Space.ACS Synth Biol2020
30666960Molecular safeguarding of CRISPR gene drive experiments.Elife2019
31589334Gene Drives: Dynamics and Regulatory Matters-A Report from the Workshop "Evaluation of Spatial and Temporal Control of Gene Drives," April 4-5, 2019, Vienna.Bioessays2019
30918006CRISPR Gene Drive Efficiency and Resistance Rate Is Highly Heritable with No Common Genetic Loci of Large Effect.Genetics2019
30679262Maximum Likelihood Estimation of Fitness Components in Experimental Evolution.Genetics2019
30517680SLiM 3: Forward Genetic Simulations Beyond the Wright-Fisher Model.Mol Biol Evol2019
30590560Evolutionary Modeling in SLiM 3 for Beginners.Mol Biol Evol2019
30565882Tree-sequence recording in SLiM opens new horizons for forward-time simulation of whole genomes.Mol Ecol Resour2019
29735716Reducing resistance allele formation in CRISPR gene drive.Proc Natl Acad Sci U S A2018
30190420Signatures of Insecticide Selection in the Genome of <i>Drosophila melanogaster</i>.G3 (Bethesda)2018
30397141Narrow thermal tolerance and low dispersal drive higher speciation in tropical mountains.Proc Natl Acad Sci U S A2018
28278350The role of the vaginal microbiome in gynaecological cancer.BJOG2018
27941126Evolution of Resistance Against CRISPR/Cas9 Gene Drive.Genetics2017
28341700asymptoticMK: A Web-Based Tool for the Asymptotic McDonald-Kreitman Test.G3 (Bethesda)2017
28727785Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations.PLoS Genet2017
27702775SLiM 2: Flexible, Interactive Forward Genetic Simulations.Mol Biol Evol2017
27546575Plumage Genes and Little Else Distinguish the Genomes of Hybridizing Warblers.Curr Biol2016
26589239Evaluating the performance of selection scans to detect selective sweeps in domestic dogs.Mol Ecol2016
27899133Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.Genome Biol2016
27185237Can Population Genetics Adapt to Rapid Evolution?Trends Genet2016
25554775Evolutionary genomics. Conundrum of jumbled mosquito genomes.Science2015
26232409Modeling the Manipulation of Natural Populations by the Mutagenic Chain Reaction.Genetics2015
25995268Quantification of GC-biased gene conversion in the human genome.Genome Res2015
25706129Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps.PLoS Genet2015
24619126Genome-wide signals of positive selection in human evolution.Genome Res2014
25060100Soft selective sweeps in complex demographic scenarios.Genetics2014
23737754Strong purifying selection at synonymous sites in D. melanogaster.PLoS Genet2013
24075201Population genomics of rapid adaptation by soft selective sweeps.Trends Ecol Evol2013
23650353Frequent adaptation and the McDonald-Kreitman test.Proc Natl Acad Sci U S A2013
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Collaborators

Jackson Champer
Cornell University
Co-authored papers 20
Dmitri A Petrov
Stanford University
Co-authored papers 14
Andrew G Clark
Co-authored papers 14
Kevin M Esvelt
Massachusetts Institute of Technology
Co-authored papers 3
Kenneth A Oye
Massachusetts Institute of Technology
Co-authored papers 1
Jeantine E Lunshof
Wyss Institute for Biologically Inspired Engineering, Harvard University
Co-authored papers 1
Robert M Friedman
J. Craig Venter Institute
Co-authored papers 1
Jason L Rasgon
The Pennsylvania State University, University Park
Co-authored papers 1
Gordana Ra??i??
Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine
Co-authored papers 1
Kanya C Long
University of California San Diego School of Medicine
Co-authored papers 1
Adam E Vorsino
University of Hawaii
Co-authored papers 1
Chun-Hong Chen
Institute of Infectious Diseases and Vaccinology, National Health Research Institutes
Co-authored papers 1
Craig Montell
University of California santa barbara
Co-authored papers 1
J Royden Saah
Co-authored papers 1
Adam Siepel
Co-authored papers 1
Larisa Rudenko
Massachusetts Institute of Technology
Co-authored papers 1
Jennifer Kuzma
North Carolina State University
Co-authored papers 1
Claudia Emerson
Institute on Ethics and Policy for Innovation, McMaster University
Co-authored papers 1
Sam Weiss Evans
Co-authored papers 1
Cinnamon Bloss
University of California
Co-authored papers 1
Andrew D Kern
Co-authored papers 1
Jeffrey G Scott
Cornell University
Co-authored papers 1
Maxwell J Scott
North Carolina State University
Co-authored papers 1
James P Collins
Arizona State University
Co-authored papers 1
David Enard
University of Arizona
Co-authored papers 1
Florence D??barre
Institute of Ecology and Environmental Sciences of Paris, Sorbonne Universite, CNRS
Co-authored papers 1
Antoinette J Piaggio
National Wildlife Research Center
Co-authored papers 1
Jolene T Sutton
University of Hawai'i at Hilo
Co-authored papers 1
George J Annas
Boston University School of Public Health.
Co-authored papers 1
Hirotaka Kanuka
Jikei University School of Medicine
Co-authored papers 1
Release 1.2