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Author Details

Alex N Nguyen Ba
University of Toronto at Mississauga
2009
30
18
PMIDPaper TitleJournal TitlePublished Year
37426450Minimum information and guidelines for reporting a Multiplexed Assay of Variant Effect.ArXiv2023
35147078Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast.Elife2022
35511982Idiosyncratic epistasis leads to global fitness-correlated trends.Science2022
35752001Microbial experimental evolution in a massively multiplexed and high-throughput era.Curr Opin Genet Dev2022
35524129Bulk-Fitness Measurements Using Barcode Sequencing Analysis in Yeast.Methods Mol Biol2022
34596043Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations.Elife2021
34849811The genetic basis of differential autodiploidization in evolving yeast populations.G3 (Bethesda)2021
32152531Chance and necessity in the pleiotropic consequences of adaptation for budding yeast.Nat Ecol Evol2020
31778298Experimental evolution for niche breadth in bacteriophage T4 highlights the importance of structural genes.Microbiologyopen2020
32587063Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials.mBio2020
32586993Exploring whole-genome duplicate gene retention with complex genetic interaction analysis.Science2020
30768593Modular epistasis and the compensatory evolution of gene deletion mutants.PLoS Genet2019
31723263High-resolution lineage tracking reveals travelling wave of adaptation in laboratory yeast.Nature2019
31264965Proteome-wide signatures of function in highly diverged intrinsically disordered regions.Elife2019
30925180Evolthon: A community endeavor to evolve lab evolution.PLoS Biol2019
29970070Short linear motifs in intrinsically disordered regions modulate HOG signaling capacity.BMC Syst Biol2018
30025666Experimental Studies of Evolutionary Dynamics in Microbes.Trends Genet2018
28122947Functional Analysis of Kinases and Transcription Factors in <i>Saccharomyces cerevisiae</i> Using an Integrated Overexpression Library.G3 (Bethesda)2017
28167781Selection maintains signaling function of a highly diverged intrinsically disordered region.Proc Natl Acad Sci U S A2017
28410373Parallel reorganization of protein function in the spindle checkpoint pathway through evolutionary paths in the fitness landscape that appear neutral in laboratory experiments.PLoS Genet2017
25966461The Structure of an NDR/LATS Kinase-Mob Complex Reveals a Novel Kinase-Coactivator System and Substrate Docking Mechanism.PLoS Biol2015
26047845Polymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions.Genome Biol Evol2015
24425782A high-definition view of functional genetic variation from natural yeast genomes.Mol Biol Evol2014
25474245Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences.PLoS Comput Biol2014
23368932High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome.BMC Genomics2013
22416277Proteome-wide discovery of evolutionary conserved sequences in disordered regions.Sci Signal2012
22302575Predicting kinase substrates using conservation of local motif density.Bioinformatics2012
20368267Evolution of characterized phosphorylation sites in budding yeast.Mol Biol Evol2010
19212322Population genomics of domestic and wild yeasts.Nature2009
19563654NLStradamus: a simple Hidden Markov Model for nuclear localization signal prediction.BMC Bioinformatics2009
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Collaborators

University of Toronto
Co-authored papers 3
University of Cambridge
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University of Toronto
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Ontario Institute for Cancer Research
Co-authored papers 1
University of Toronto
Co-authored papers 1
Harvard Medical School
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University of Helsinki
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Stanford University
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Stanford University
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Hospital for Sick Children
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Institute of Bioengineering of Catalonia (IBEC)
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Earlham Institute
Co-authored papers 1
Charite - Universitatsmedizin Berlin
Co-authored papers 1
Clinical Genetics, Addenbrooke's Hospital, Cambridge University Hospitals
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
University of Georgia
Co-authored papers 1
The Jackson Laboratory Cancer Center
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
University of Toronto, University Avenue
Co-authored papers 1
Vanderbilt University
Co-authored papers 1
The Walter and Eliza Hall Institute of Medical Research
Co-authored papers 1
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University of Washington
Co-authored papers 1
University of Minnesota - Twin Cities
Co-authored papers 1
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Ontario Institute for Cancer Research
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University of Toronto
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