Author details

Full Name

Mark L Grimes

Affiliation

ORCID

Career Start Year

1982

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36996232	Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer.		2023
34615962	Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates Î±5Î²1 integrin endocytosis.	Sci Rep	2021
32726167	PAG1 directs SRC-family kinase intracellular localization to mediate receptor tyrosine kinase-induced differentiation.	Molecular Biology of the Cell	2020
29789295	Integration of protein phosphorylation, acetylation, and methylation data sets to outline lung cancer signaling networks.	Sci Signal	2018
28994825	Clustergrammer, a web-based heatmap visualization and analysis tool for high-dimensional biological data.	Sci Data	2017
25884760	Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts.	PLoS Comput Biol	2015
23549480	SH3 interactome conserves general function over specific form.	Mol Syst Biol	2013
23837656	RCytoscape: tools for exploratory network analysis.	BMC Bioinformatics	2013
23300999	Wrangling phosphoproteomic data to elucidate cancer signaling pathways.	PLoS One	2013
22496904	NGF causes TrkA to specifically attract microtubules to lipid rafts.	PLoS ONE	2012
19416476	High-resolution fractionation of signaling endosomes containing different receptors.	Traffic	2009
19625404	Assembly of arenavirus envelope glycoprotein GPC in detergent-soluble membrane microdomains.	J Virol	2009
17000777	APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction.	Mol Cell Biol	2006
15500439	Distinct signalling particles containing ERK/MEK and B-Raf in PC12 cells.	Biochemical Journal	2005
14994338	Comparison of nerve terminal events in vivo effecting retrograde transport of vesicles containing neurotrophins or synaptic vesicle components.	Journal of Neuroscience Research	2004
12603816	Receptor tyrosine kinase and G-protein coupled receptor signaling and sorting within endosomes.	Journal of Neurochemistry	2003
11640893	A population of PC12 cells that is initiating apoptosis can be rescued by nerve growth factor.	Molecular and Cellular Neurosciences	2001
11119719	CREB is cleaved by caspases during neural cell apoptosis.	FEBS Letters	2000
10352686	The role of retinoid metabolism by alcohol and aldehyde dehydrogenases in differentiation of cultured neuronal cells.	Advances in Experimental Medicine and Biology	1999
10501228	Phosphorylation-dependent Akt cleavage in neural cell in vitro reconstitution of apoptosis.	Journal of Neurochemistry	1999
9275225	A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA.	Proc Natl Acad Sci U S A	1997
8987823	Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes.	J Neurosci	1996
9246468	A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration.	Cold Spring Harb Symp Quant Biol	1996
7543930	Multiple levels for regulation of TrkA in PC12 cells by nerve growth factor.	J Neurochem	1995
1572894	Intermediates in the constitutive and regulated secretory pathways released in vitro from semi-intact cells.	Journal of Cell Biology	1992
1288369	Sorting of chromogranin B into immature secretory granules in pheochromocytoma (PC12) cells.	Annals of the New York Academy of Sciences	1992
1779968	The bovine chromogranin A gene: structural basis for hormone regulation and generation of biologically active peptides.	Molecular Endocrinology	1991
2709813	Chromogranin A and B messenger ribonucleic acids in pituitary and other normal and neoplastic human endocrine tissues.	Laboratory Investigation	1989
3473966	Chromogranin A: the primary structure deduced from cDNA clones reveals the presence of pairs of basic amino acids.	Annals of the New York Academy of Sciences	1987
3018587	Bovine chromogranin A sequence and distribution of its messenger RNA in endocrine tissues.	Nature	1986
3995004	Affinity-dependent cross-linking to neurotoxin sites of the acetylcholine receptor mediated by catechol oxidation.	Biochemistry	1985
7138537	Affinity directed reactions of 3-trimethylaminomethyl catechol with the acetylcholine receptor from Torpedo californica.	Biochemical and Biophysical Research Communications	1982