Skip to Main Content

Author Details

David Langlais
McGill University
2008
51
21
PMIDPaper TitleJournal TitlePublished Year
36736301Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria.Cell2023
37996443The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome.Nat Commun2023
37087735Identification and analysis of the DNA content of small extracellular vesicles isolated from Leishmania parasites.STAR Protoc2023
37350957Thermoneutrality and severe malaria: investigating the effect of warmer environmental temperatures on the inflammatory response and disease progression.Front Immunol2023
36515678Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency.J Exp Med2023
36738766Histone H2A deubiquitinases in the transcriptional programs of development and hematopoiesis: a consolidated analysis.Int J Biochem Cell Biol2023
35883188CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells.Stem Cell Res Ther2022
35648852A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19.Sci Adv2022
35858561Leishmania parasites exchange drug-resistance genes through extracellular vesicles.Cell Rep2022
36327219Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative.PLoS Genet2022
34114734Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma.J Cell Mol Med2021
33912157Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1.Front Immunol2021
34858388Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1⿿3)-β-D-Glucan.Front Immunol2021
34972189The role of Leishmania GP63 in the modulation of innate inflammatory response to Leishmania major infection.PLoS One2021
34707143The c-Rel transcription factor limits early interferon and neuroinflammatory responses to prevent herpes simplex encephalitis onset in mice.Sci Rep2021
34625535p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress.Cell Death Dis2021
34623332Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents.J Clin Invest2021
34531456A forward genetic screen identifies modifiers of rocaglate responsiveness.Sci Rep2021
34183838Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child.Nat Med2021
34214472Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy.Cell2021
32344625Deubiquitinase MYSM1 in the Hematopoietic System and beyond: A Current Review.Int J Mol Sci2020
31792077ZBTB7B (ThPOK) Is Required for Pathogenesis of Cerebral Malaria and Protection against Pulmonary Tuberculosis.Infect Immun2020
32641579MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction.JCI Insight2020
30639577USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B-cell-mediated immune response in a mouse model.Exp Hematol2019
31827213Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer.Sci Rep2019
29463745Rocaglates as dual-targeting agents for experimental cerebral malaria.Proc Natl Acad Sci U S A2018
30127434Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.Nat Immunol2018
29922917Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei.Mamm Genome2018
27912315Genetics of Infectious and Inflammatory Diseases: Overlapping Discoveries from Association and Exome-Sequencing Studies.Annu Rev Immunol2017
28760770Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus.Clin Sci (Lond)2017
27721430USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.Nat Immunol2017
26695862The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease.J Clin Endocrinol Metab2016
27849203Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.Nat Immunol2016
27974206Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.Cell Rep2016
26979842Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice.Mamm Genome2016
26768662Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.Cell Death Differ2016
26791050Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection.Trends Immunol2016
27001747The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.J Exp Med2016
25710881p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency.Blood2015
25122610Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation.Blood2014
25473962Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection.PLoS Pathog2014
25403443CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.J Exp Med2014
24973457Genetic control of susceptibility to Candida albicans in SM/J mice.J Immunol2014
23754801Adult pituitary cell maintenance: lineage-specific contribution of self-duplication.Mol Endocrinol2013
24385922Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs.PLoS Genet2013
24105479Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice.Endocrinology2013
23853600Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.PLoS Pathog2013
22633955The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome.Mol Cell2012
21193556A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells.Mol Endocrinol2011
21731497Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis.PLoS Genet2011
  • 1 - 50 of 51

Recommended Authors

James Fitch
The Institute for Genomic Medicine, Nationwide Children's Hospital
Career Start Year 2015
Number of shared co-authors 0
Steven Witte
University of Alabama at Birmingham
Career Start Year 2014
Number of shared co-authors 0
Ang Cui
Massachusetts Institute of Technology
Career Start Year 2013
Number of shared co-authors 1
Paulo Czarnewski
Karolinska Institute, Center for Molecular Medicine
Career Start Year 2012
Number of shared co-authors 1
Huiyuan Zhang
Texas Children's Cancer Center
Career Start Year 2010
Number of shared co-authors 0
Vinod Kumar
The University of Queensland
Career Start Year 2008
Number of shared co-authors 8
Matthias Farlik
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Career Start Year 2007
Number of shared co-authors 0
Deborah R Winter
Northwestern University Feinberg School of Medicine
Career Start Year 2007
Number of shared co-authors 1
Ryan A Flynn
Boston Children's Hospital
Career Start Year 2006
Number of shared co-authors 0
Maggie Cam
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 2005
Number of shared co-authors 2
Kun Qu
University of Science and Technology of China
Career Start Year 2005
Number of shared co-authors 0
Christopher Benner
Michigan State University College of Human Medicine
Career Start Year 2004
Number of shared co-authors 2
Ido Amit
Weizmann Institute of Science
Career Start Year 2004
Number of shared co-authors 5
Andrew V Kossenkov
The Wistar Institute
Career Start Year 2003
Number of shared co-authors 0
Matthew T Weirauch
University of Cincinnati College of Medicine
Career Start Year 2003
Number of shared co-authors 6
David J Lynn
South Australian Health and Medical Research Institute
Career Start Year 2002
Number of shared co-authors 1
Hans-J??rg Warnatz
Max Planck Institute for Molecular Genetics
Career Start Year 2002
Number of shared co-authors 2
Mikhail G Dozmorov
Virginia Commonwealth University
Career Start Year 2001
Number of shared co-authors 1
Sophia Derdak
Medical University of Vienna
Career Start Year 2001
Number of shared co-authors 2
Andrew Wang
Yale University School of Medicine
Career Start Year 2001
Number of shared co-authors 0
Sven Heinz
U.C. San Diego School of Medicine
Career Start Year 2000
Number of shared co-authors 3
Peter White
The Ohio State University
Career Start Year 2000
Number of shared co-authors 1
David K Crossman
University of Alabama at Birmingham
Career Start Year 2000
Number of shared co-authors 1
Julian C Knight
University of Oxford
Career Start Year 1997
Number of shared co-authors 7
Michael Rehli
University Hospital Regensburg
Career Start Year 1995
Number of shared co-authors 2
Jenny Xiang
Caryl and Israel Englander Institute for Precision Medicine.
Career Start Year 1993
Number of shared co-authors 0
Christine A Wells
The University of Melbourne
Career Start Year 1989
Number of shared co-authors 2
Nir Hacohen
Broad Institute of MIT and Harvard
Career Start Year 1989
Number of shared co-authors 8
Ramnik J Xavier
Broad Institute of MIT and Harvard
Career Start Year 1989
Number of shared co-authors 11
Bruce J Aronow
Cincinnati Children's Hospital Medical Center
Career Start Year 1975
Number of shared co-authors 0

Collaborators

Anastasia Nijnik
McGill University
Co-authored papers 11
Mathieu Bourgey
McGill University
Co-authored papers 6
Jacques Drouin
Institut de recherches cliniques de Montreal (IRCM)
Co-authored papers 6
Mark Lathrop
Victor Philip Dahdaleh Institute of Genomic Medicine at McGill University
Co-authored papers 5
Joanne Berghout
Co-authored papers 4
Guillaume Bourque
Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University
Co-authored papers 3
Klaus-Peter Knobeloch
Co-authored papers 2
Szymon Pula
Co-authored papers 1
Albandari Binowayn
King Fahad Medical City and King Abdulaziz City for Science and Technology
Co-authored papers 1
Nattiya Hirankarn
Chulalongkorn University
Co-authored papers 1
Ho Namkoong
Keio University School of Medicine
Co-authored papers 1
Mathieu Quinodoz
Institute of Molecular and Clinical Ophthalmology Basel (IOB)
Co-authored papers 1
Daniel M Jordan
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Noam D Beckmann
Icahn School of Medicine at Mount Sinai.
Co-authored papers 1
Antonio Salas
Instituto de Investigacion Sanitaria de Santiago
Co-authored papers 1
Timothy Sanders
David Geffen School of Medicine, University of California-Los Angeles
Co-authored papers 1
Nicole Simons
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Efren Sandoval
Co-authored papers 1
Carlo Rivolta
Institute of Molecular and Clinical Ophthalmology Basel (IOB)
Co-authored papers 1
Monnat Pongpanich
Chulalongkorn University
Co-authored papers 1
Joseph D Buxbaum
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Francisco Tanudjaja
Co-authored papers 1
Mateusz Sypniewski
MNM Bioscience Inc.
Co-authored papers 1
Christoph Klein
Kinderklinik und Kinderpoliklinik der Ludwig-Maximilians-Universitat Munchen
Co-authored papers 1
Yanara Marincevic-Zuniga
Uppsala University
Co-authored papers 1
Alexandre Bolze
The Rockefeller University
Co-authored papers 1
Shaun Dabe
Co-authored papers 1
Ebtehal A Alsolm
King Fahad Medical City and King Abdulaziz City for Science and Technology
Co-authored papers 1
Tatsuhiko Naito
Osaka University Graduate School of Medicine
Co-authored papers 1
Olaf Riess
Institute of Medical Genetics and Applied Genomics, University of Tuebingen
Co-authored papers 1
Release 1.2