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Author Details

Daniel S Brewer
University of Washington, USA Institute for Stem Cell and Regenerative Medicine
2003
63
28
PMIDPaper TitleJournal TitlePublished Year
36493777Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs.Stem Cell Reports2023
37555750Caution regarding the specificities of pan-cancer microbial structure.Microb Genom2023
37577699Major data analysis errors invalidate cancer microbiome findings.bioRxiv2023
37258856Quality Control in Metagenomics Data.Methods Mol Biol2023
36920900Whole exome sequencing study identifies candidate loss of function variants and locus heterogeneity in familial cholesteatoma.PLoS One2023
36765747Gene-Transcript Expression in Urine Supernatant and Urine Cell-Sediment Are Different but Equally Useful for Detecting Prostate Cancer.Cancers (Basel)2023
36661662Combining Molecular Subtypes with Multivariable Clinical Models Has the Potential to Improve Prediction of Treatment Outcomes in Prostate Cancer at Diagnosis.Curr Oncol2022
35597990APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types.BMC Biol2022
35454901A Model to Detect Significant Prostate Cancer Integrating Urinary Peptide and Extracellular Vesicle RNA Data.Cancers (Basel)2022
35659150Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study.Eur Urol2022
35450835Microbiomes of Urine and the Prostate Are Linked to Human Prostate Cancer Risk Groups.Eur Urol Oncol2022
33925381Integration of Urinary EN2 Protein & Cell-Free RNA Data in the Development of a Multivariable Risk Model for the Detection of Prostate Cancer Prior to Biopsy.Cancers (Basel)2021
32203215A novel stratification framework for predicting outcome in patients with prostate cancer.Br J Cancer2020
31779479Methodology for the at-home collection of urine samples for prostate cancer detection.Biotechniques2020
33033260Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy.Nat Commun2020
32708551Convergence of Prognostic Gene Signatures Suggests Underlying Mechanisms of Human Prostate Cancer Progression.Genes (Basel)2020
32153047Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer.Prostate2020
31106513A four-group urine risk classifier for predicting outcomes in patients with prostate cancer.BJU Int2019
32055707Potential for diagnosis of infectious disease from the 100,000 Genomes Project Metagenomic Dataset: Recommendations for reporting results.Wellcome Open Res2019
31639030SEPATH: benchmarking the search for pathogens in human tissue whole genome sequence data leads to template pipelines.Genome Biol2019
30801051epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer.JCO Precis Oncol2019
30971929Transcriptome-Wide Effects of Sphingosine Kinases Knockdown in Metastatic Prostate and Breast Cancer Cells: Implications for Therapeutic Targeting.Front Pharmacol2019
28753852DESNT: A Poor Prognosis Category of Human Prostate Cancer.Eur Urol Focus2018
30470249A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer.Clin Epigenetics2018
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
28945760Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.PLoS Genet2017
26455355Prostate Single Nucleotide Polymorphism Provides a Crucial Clue to Cancer Aggression in Active Surveillance Patients.Eur Urol2016
24913504A gene expression based predictor for high risk myeloma treated with intensive therapy and autologous stem cell rescue.Leuk Lymphoma2015
25830880The evolutionary history of lethal metastatic prostate cancer.Nature2015
26018901Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Nat Genet2015
25730763Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Nat Genet2015
25586381Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing.J Clin Pathol2015
25560400HES5 silencing is an early and recurrent change in prostate tumourigenesis.Endocr Relat Cancer2015
24481405Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer.Br J Cancer2014
25271376Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.Elife2014
25297811Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice.BMC Genomics2014
25082706Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.Science2014
24811243Poly(amidoamine) dendrimer nanocarriers and their aerosol formulations for siRNA delivery to the lung epithelium.Mol Pharm2014
23718138Improved risk stratification in myeloma using a microRNA-based classifier.Br J Haematol2013
23695019Prognostic value of PTEN loss in men with conservatively managed localised prostate cancer.Br J Cancer2013
21982899Propellant-based inhalers for the non-invasive delivery of genes via oral inhalation.J Control Release2012
23059046Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study.Lancet Oncol2012
22460813Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in prostate cancer.Mod Pathol2012
21632985A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma.Sci Transl Med2011
21856767A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment.Clin Cancer Res2011
21799931siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer.PLoS One2011
20104229Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer.Br J Cancer2010
21779455PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention.Genes Cancer2010
20029424A census of amplified and overexpressed human cancer genes.Nat Rev Cancer2010
19040532Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer.BJU Int2009
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Collaborators

Colin S Cooper
Norwich Medical School, University of East Anglia
Co-authored papers 41
Jeremy Clark
Norwich Medical School, University of East Anglia
Co-authored papers 24
Rosalind A Eeles
The Institute of Cancer Research
Co-authored papers 15
Christopher S Foster
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Co-authored papers 12
Rachel Hurst
Seattle Children's Research Institute (K Liljenquist
Co-authored papers 12
Hayley C Whitaker
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David C Wedge
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Co-authored papers 10
Andy G Lynch
University of St Andrews
Co-authored papers 10
David E Neal
University of Oxford, John Radcliffe Hospital
Co-authored papers 9
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Memorial Sloan Kettering Cancer Center
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The Institute of Cancer Research
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Johann S de Bono
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Anne Y Warren
Cambridge University Hospitals National Health Service Foundation Trust
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Ultan McDermott
Wellcome Sanger Institute
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Charlie E Massie
University of Cambridge
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Daniel M Berney
Barts Cancer Institute, Queen Mary University of London
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Alan Thompson
The Royal Marsden NHS Foundation Trust
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Adam Butler
Wellcome Sanger Institute
Co-authored papers 7
Sandra Edwards
The Institute of Cancer Research
Co-authored papers 7
Ludmil B Alexandrov
Moores Cancer Center, university of california san diego
Co-authored papers 6
Cyril Fisher
University Hospitals Birmingham NHS Foundation Trust
Co-authored papers 6
Chris Ogden
The Royal Marsden Hospital NHS Foundation Trust
Co-authored papers 6
Cathy Corbishley
The Institute of Cancer Research
Co-authored papers 6
Tapio Visakorpi
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 6
Vincent J Gnanapragasam
University of Cambridge
Co-authored papers 6
Peter Van Loo
The Francis Crick Institute
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Nening Dennis
Institute of Cancer Research
Co-authored papers 6
George Steven Bova
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
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Gerhardt Attard
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