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Author Details
Full Name
Brian T Chait
Affiliation
The Rockefeller University
ORCID
Career Start Year
1984
Papers
387
H Index
107
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37503298
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus.
bioRxiv
2024
37503298
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus.
bioRxiv
2024
36747644
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker.
bioRxiv
2023
37738963
Implications of a multiscale structure of the yeast nuclear pore complex.
Mol Cell
2023
37808863
Using a function-first 'scout fragment'-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes.
bioRxiv
2023
37333354
Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes.
bioRxiv
2023
37066338
Dynamic molecular mechanism of the nuclear pore complex permeability barrier.
bioRxiv
2023
36943866
Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep
2023
36695784
A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division.
J Cell Biol
2023
36747644
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker.
bioRxiv
2023
36920247
A general method for quantitative fractionation of mammalian cells.
J Cell Biol
2023
36720309
Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2.
J Biol Chem
2023
37738963
Implications of a multiscale structure of the yeast nuclear pore complex.
Mol Cell
2023
37808863
Using a function-first 'scout fragment'-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes.
bioRxiv
2023
36943866
Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep
2023
37333354
Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes.
bioRxiv
2023
37066338
Dynamic molecular mechanism of the nuclear pore complex permeability barrier.
bioRxiv
2023
36695784
A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division.
J Cell Biol
2023
36720309
Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2.
J Biol Chem
2023
36920247
A general method for quantitative fractionation of mammalian cells.
J Cell Biol
2023
35147499
The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates.
Elife
2022
35970830
Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun
2022
35948425
Evidence for Plant-Conserved Region Mediated Trimeric CESAs in Plant Cellulose Synthase Complexes.
Biomacromolecules
2022
35881804
Shelterin is a dimeric complex with extensive structural heterogeneity.
Proc Natl Acad Sci U S A
2022
35367208
Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease.
J Biol Chem
2022
34982960
Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell
2022
35147499
The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates.
Elife
2022
35367208
Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease.
J Biol Chem
2022
35970830
Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun
2022
35948425
Evidence for Plant-Conserved Region Mediated Trimeric CESAs in Plant Cellulose Synthase Complexes.
Biomacromolecules
2022
35881804
Shelterin is a dimeric complex with extensive structural heterogeneity.
Proc Natl Acad Sci U S A
2022
34982960
Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell
2022
33412588
A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.
Nucleic Acids Res
2021
34297925
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.
Cell
2021
33536617
Dynamic regulation of T<sub>FH</sub> selection during the germinal centre reaction.
Nature
2021
33480355
Structural basis for transcription complex disruption by the Mfd translocase.
Elife
2021
33851164
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.
bioRxiv
2021
33883267
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc Natl Acad Sci U S A
2021
33758867
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
bioRxiv
2021
33496729
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function.
J Cell Biol
2021
33333016
Dissecting the Structural Dynamics of the Nuclear Pore Complex.
Mol Cell
2021
33217329
Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM.
Structure
2021
33412588
A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.
Nucleic Acids Res
2021
33393463
Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake.
Elife
2021
34374644
Analysis of the mechanosensor channel functionality of TACAN.
Elife
2021
34874007
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.
Elife
2021
34527957
Measuring <i>in vivo</i> protein turnover and exchange in yeast macromolecular assemblies.
STAR Protoc
2021
33883267
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc Natl Acad Sci U S A
2021
33851164
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.
bioRxiv
2021
33758867
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
bioRxiv
2021
1 - 50 of 774
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Rosemary Williams
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University of Dundee
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Yingming Zhao
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Peter C Fridy
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Co-authored papers
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Yinyin Li
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