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Author Details

Lin Leng
Yale University School of Medicine
1984
230
57
Wade Schulz (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37935315Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity.Mol Metab2024
36222594MIF is a common genetic determinant of COVID-19 symptomatic infection and severity.QJM2023
37790522The RhoA GTPase regulates Type I Interferon Signaling in Systemic lupus erythematosus.Res Sq2023
37088943Effects of Orthokeratology Lens Decentration Induced by Paracentral Corneal Asymmetry on Axial Length Elongation.Eye Contact Lens2023
37283810A pref-1-controlled non-inflammatory mechanism of insulin resistance.iScience2023
37408274Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain.Cells2023
37261103The Influence of Accommodation on Retinal Peripheral Refraction Changes in Different Measurement Areas.J Ophthalmol2023
36401063Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Clin Rheumatol2023
36509642Repeatability and correlation of corneal biomechanical measurements obtained by Corvis ST in orthokeratology patients.Cont Lens Anterior Eye2023
36565380Correction to: Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Clin Rheumatol2023
36223730Incidence and Risk Factors of Repositioning Surgery to Correct Misalignment of Toric Intraocular Lenses after Cataract Surgery: A Single-Center Retrospective Observational Study.Ophthalmic Res2023
35186691Comparison of efficacy of two different silicone hydrogel bandage contact lenses after T-PRK.Int J Ophthalmol2022
35645739Bladder Oxidative Stress and HMGB1 Release Contribute to PAR4-Mediated Bladder Pain in Mice.Front Syst Neurosci2022
35372397Comparison of Anterior Capsule Polishing on the Rate of Neodymium: YAG Laser Capsulotomy After Two Multifocal Intraocular Lens Implantation.Front Med (Lausanne)2022
36298774Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV Infection.Viruses2022
36323260CD74 as a regulator of transcription in normal B cells.Cell Rep2022
36052009Temporal and spatial characterization of myopia in China.Front Public Health2022
33328325Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independently of its receptor complex CD74/CD44.J Cell Sci2021
33566866The impact of cataract progression on accuracy of intraocular lens power measurement.PLoS One2021
33844457ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the MIF Immune Susceptibility Locus.Arthritis Rheumatol2021
34850744MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model.J Clin Invest2021
34957151Agreement and Repeatability of Central and Peripheral Refraction by One Novel Multispectral-Based Refractor.Front Med (Lausanne)2021
34669443Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease.Sci Transl Med2021
34424927Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain.PLoS One2021
34719814Suppression of Plasmodium MIF-CD74 signaling protects against severe malaria.FASEB J2021
33945507Role of MIF in coordinated expression of hepatic chemokines in patients with alcohol-associated hepatitis.JCI Insight2021
32932965The <i>Macrophage Migration Inhibitory Factor</i> (<i>MIF</i>) Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery.J Clin Med2020
31961019Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF-2 in adipose tissue during endotoxemia.FASEB J2020
31745872Genotyping Two Promoter Polymorphisms in the MIF Gene: A -794 CATT<sub>5-8</sub> Microsatellite Repeat and a -173 G/C SNP.Methods Mol Biol2020
33239628Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.Nat Commun2020
33264374Macrophage Migration Inhibitory Factor is not Associated with Sarcoidosis Susceptibility or Severity in Whites or Blacks.Sarcoidosis Vasc Diffuse Lung Dis2020
32633675Molecular MRI of the Immuno-Metabolic Interplay in a Rabbit Liver Tumor Model: A Biomarker for Resistance Mechanisms in Tumor-targeted Therapy?Radiology2020
32625208Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression.Front Immunol2020
30520689A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity.Am J Physiol Lung Cell Mol Physiol2019
33604547Low expression <i>Macrophage Migration Inhibitory Factor (MIF)</i> alleles and tuberculosis in HIV infected South Africans.Cytokine X2019
30252532Endothelial cell-secreted MIF reduces pericyte contractility and enhances neutrophil extravasation.FASEB J2019
30009530Macrophage Migration Inhibitory Factor Regulates U1 Small Nuclear RNP Immune Complex-Mediated Activation of the NLRP3 Inflammasome.Arthritis Rheumatol2019
31499270The small molecule macrophage migration inhibitory factor antagonist MIF098, inhibits pulmonary hypertension associated with murine SLE.Int Immunopharmacol2019
31608058MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654.Front Immunol2019
31292300Macrophage migration inhibitory factor enhances influenza-associated mortality in mice.JCI Insight2019
31236345Compound heterozygous mutations in <i>CYP1B1</i> gene leads to severe primary congenital glaucoma phenotype.Int J Ophthalmol2019
31578280A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity.J Biol Chem2019
31289792MIF mediates bladder pain, not inflammation, in cyclophosphamide cystitis.Cytokine X2019
31484822Cardiomyocyte d-dopachrome tautomerase protects against heart failure.JCI Insight2019
30708129Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain.Neurosci Lett2019
31009094Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response After Ethanol Feeding in Mice.Alcohol Clin Exp Res2019
30787934miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1.Front Immunol2019
30817226Macrophage migration inhibitory factor regulates innate γδ T-cell responses <i>via</i> IL-17 expression.FASEB J2019
29287304The Tumor-Like Phenotype of Rheumatoid Synovium: Molecular Profiling and Prospects for Precision Medicine.Arthritis Rheumatol2018
29843083SIRT7 regulates the TGF-β1-induced proliferation and migration of mouse airway smooth muscle cells by modulating the expression of TGF-β receptor I.Biomed Pharmacother2018
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Collaborators

Yale University School of Medicine
Co-authored papers 197
Yale University School of Medicine
Co-authored papers 16
Yale School of Medicine
Co-authored papers 12
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Co-authored papers 6
Co-authored papers 6
Aix Marseille Universite, INSERM, CNRS
Co-authored papers 6
Yale School of Medicine
Co-authored papers 5
Trinity College Dublin
Co-authored papers 4
Yale School of Medicine
Co-authored papers 3
Yale University
Co-authored papers 3
The State University of New Jersey
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 2
Yale School of Medicine, Yale University
Co-authored papers 2
University Hospital RWTH Aachen
Co-authored papers 2
Discovery and Preclinical Sciences
Co-authored papers 2
Co-authored papers 2
University Hospital Munster
Co-authored papers 2
Clinic for Plastic, Otto von Guericke University
Co-authored papers 1
Yale University School of Medicine
Co-authored papers 1
Moffit Cancer Center
Co-authored papers 1
Co-authored papers 1
Zhongnan Hospital of Wuhan University
Co-authored papers 1
Co-authored papers 1
University of Texas McGovern Medical School
Co-authored papers 1
Yale University School of Medicine
Co-authored papers 1
Yale School of Medicine
Co-authored papers 1
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