Author details

Full Name

Dirk S Paul

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36991119	An atlas of genetic scores to predict multi-omic traits.	Nature	2023
37563310	Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
36653562	FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
36829046	Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
36809768	Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank.	Am J Hum Genet	2023
36993312	Genetic regulation of fetal hemoglobin across global populations.	medRxiv	2023
35264566	Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.	Nat Commun	2022
35388009	Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.	Nat Commun	2022
35736394	Pharmacogenomic study of heart failure and candesartan response from the CHARM programme.	ESC Heart Fail	2022
36383675	Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.	Sci Adv	2022
36446790	Genetically personalised organ-specific metabolic models in health and disease.	Nat Commun	2022
35916366	Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans.	Elife	2022
34503513	Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.	BMC Med	2021
33851187	Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.	medRxiv	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
33326012	Assessing the Role of Rare Genetic Variation in Patients With Heart Failure.	JAMA Cardiol	2021
33230300	Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2020
30664780	Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.	Nat Med	2019
30239796	ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.	Nucleic Acids Res	2019
30618377	Genetic effects on promoter usage are highly context-specific and contribute to complex traits.	eLife	2019
31064398	Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.	Genome Biol	2019
30887811	An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.	J Proteome Res	2019
29459775	Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.	Nat Commun	2018
30355600	Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.	Genome Res	2018
29884221	Tensorial blind source separation for improved analysis of multi-omic data.	Genome Biol	2018
29875488	Genomic atlas of the human plasma proteome.	Nature	2018
30482885	Cell and tissue type independent age-associated DNA methylation changes are not rare but common.	Aging (Albany NY)	2018
30176915	Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins.	Genome Med	2018
29676281	Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599â¿¿912 current drinkers in 83 prospective studies.	Lancet	2018
29251357	Epigenetic and Transcriptional Variability Shape Phenotypic Plasticity.	Bioessays	2018
28126036	Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.	Genome Biol	2017
28334838	Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma.	Hum Mol Genet	2017
28530674	Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.	Nat Genet	2017
28283040	Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.	Genome Biol	2017
28163793	UroMark-a urinary biomarker assay for the detection of bladder cancer.	Clin Epigenetics	2017
27863251	Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.	Cell	2016
27318201	PhenoScanner: a database of human genotype-phenotype associations.	Bioinformatics	2016
27898055	Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.	Nat Commun	2016
27851974	eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data.	Cell Rep	2016
27716309	Correlation of an epigenetic mitotic clock with cancer risk.	Genome Biol	2016
27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Cell	2016
26669438	A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.	Genome Med	2015
25092140	Advances in epigenome-wide association studies for common diseases.	Trends Mol Med	2014
25587359	Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics.	Genome Med	2014
24311363	Functional interpretation of non-coding sequence variation: concepts and challenges.	Bioessays	2014
24518816	Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.	Epigenetics	2014
23570689	Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci.	Genome Res	2013
23222517	Seventy-five genetic loci influencing the human red blood cell.	Nature	2012
22972982	A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.	Blood	2012
22366785	Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome.	Nat Genet	2012