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Author Details

Maofu Liao
Harvard Medical School
2000
50
31
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36889459Activity and Structural Dynamics of Human ABCA1 in a Lipid Membrane.J Mol Biol2023
37316513The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.Nat Commun2023
37248213Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.Nat Commun2023
35210614Seipin forms a flexible cage at lipid droplet formation sites.Nat Struct Mol Biol2022
35501384Sub-3-ÿ cryo-EM structure of RNA enabled by engineered homomeric self-assembly.Nat Methods2022
36151501Cryo-EM Analysis of the Lipopolysaccharide Flippase MsbA.Methods Mol Biol2022
33141631The ABCs of Sterol Transport.Annu Rev Physiol2021
34554829Distinct allosteric mechanisms of first-generation MsbA inhibitors.Science2021
34344901Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins.Nat Commun2021
32433611Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.Nature2020
32814813Bedaquiline inhibits the yeast and human mitochondrial ATP synthases.Commun Biol2020
32335504High-resolution views of lipopolysaccharide translocation driven by ABC transporters MsbA and LptB<sub>2</sub>FGC.Curr Opin Struct Biol2020
32385283ABCG2 transports anticancer drugs via a closed-to-open switch.Nat Commun2020
32327568Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.Science2020
32494073Structure and mechanism of the mitochondrial Ca<sup>2+</sup> uniporter holocomplex.Nature2020
30542158Structural basis of coreceptor recognition by HIV-1 envelope spike.Nature2019
31282860Large protein organelles form a new iron sequestration system with high storage capacity.Elife2019
31367042Structure and mechanism of the cation-chloride cotransporter NKCC1.Nature2019
30894744Structural basis of lipopolysaccharide extraction by the LptB<sub>2</sub>FGC complex.Nature2019
29650704High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.Science2018
29995856X-ray and cryo-EM structures of the mitochondrial calcium uniporter.Nature2018
29880725Structure basis for RNA-guided DNA degradation by Cascade and Cas3.Science2018
30061602DNA melting initiates the RAG catalytic pathway.Nat Struct Mol Biol2018
30327422Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.J Cell Biol2018
29572442A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.Nat Commun2018
29462788Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from <i>Streptococcus gordonii</i>.J Biol Chem2018
28682307Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.Nature2017
28666122Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.Cell2017
28869968Structural basis of MsbA-mediated lipopolysaccharide transport.Nature2017
26470917Single-particle electron microscopy in the study of membrane protein structure.Microscopy (Oxf)2016
26686638Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.Cell Rep2015
26548953Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.Cell2015
24681231Single particle electron cryo-microscopy of a mammalian ion channel.Curr Opin Struct Biol2014
25417161Allosteric communication in the dynein motor domain.Cell2014
23485968A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly.Nature2013
24305161TRPV1 structures in distinct conformations reveal activation mechanisms.Nature2013
24305160Structure of the TRPV1 ion channel determined by electron cryo-microscopy.Nature2013
22483106Fabs enable single particle cryoEM studies of small proteins.Structure2012
23093611A method for integrative structure determination of protein-protein complexes.Bioinformatics2012
19912576HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.Traffic2010
21546978Alphavirus Entry and Membrane Fusion.Viruses2010
20335260In vitro reconstitution reveals key intermediate states of trimer formation by the dengue virus membrane fusion protein.J Virol2010
18632857Differential cholesterol binding by class II fusion proteins determines membrane fusion properties.J Virol2008
16971447Functions of the stem region of the Semliki Forest virus fusion protein during virus fusion and assembly.J Virol2006
16973563Site-directed antibodies against the stem region reveal low pH-induced conformational changes of the Semliki Forest virus fusion protein.J Virol2006
15661173The conserved glycine residues in the transmembrane domain of the Semliki Forest virus fusion protein are not required for assembly and fusion.Virology2005
16216925Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion.J Cell Biol2005
15016852Multistep regulation of membrane insertion of the fusion peptide of Semliki Forest virus.J Virol2004
10822100Induction of high level of specific antibody response to the neutralizing epitope ELDKWA on HIV-1 gp41 by peptide-vaccine.Peptides2000
10776789Epitope-vaccines: a new strategy to induce high levels of neutralizing antibodies against HIV-1.Immunobiology2000
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Collaborators

Yifan Cheng
Quantitative Bioscience Institute, University of California san francisco
Co-authored papers 8
Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 5
Robert V Farese
Harvard T.H. Chan School of Public Health
Co-authored papers 5
Chen Xu
University of Massachusetts Chan Medical School
Co-authored papers 4
Kangkang Song
University of Massachusetts Chan Medical School
Co-authored papers 3
Frank DiMaio
University of Washington
Co-authored papers 3
Andrea Rossi
Pfizer Inc.
Co-authored papers 2
Agustin Avila-Sakar
Lawrence Berkeley National Laboratory, University of California
Co-authored papers 2
Shenping Wu
Yale University
Co-authored papers 2
Pavel Strop
Pfizer Inc.
Co-authored papers 2
Pamela A Silver
Harvard Medical School
Co-authored papers 1
Debora S Marks
Blavatnik Institute, Harvard Medical School
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Michael S Diamond
Washington University School of Medicine
Co-authored papers 1
Boris Matija Peterlin
University of California at San Francisco
Co-authored papers 1
Volker D??tsch
Institute for Biophysical Chemistry, Goethe-University
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Ana Plemenitas
Institute of Biochemistry and Molecular Genetics, University of Ljubljana
Co-authored papers 1
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Bing Chen
Co-authored papers 1
Gregory A Voth
Co-authored papers 1
Ho Min Kim
Center for Biomolecular and Cellular Structure, Institute for Basic Science (IBS)
Co-authored papers 1
David Baker
University of Washington
Co-authored papers 1
Metka Lenassi
Institute of Biochemistry and Molecular Genetics, University of Ljubljana
Co-authored papers 1
Javier A Vel??zquez-Muriel
University of California san francisco
Co-authored papers 1
Tomaz Vaupotic
Institute of Biochemistry, University of Ljubljana
Co-authored papers 1
Sheila M Keating
University of California San Francisco
Co-authored papers 1
Koen Bartholomeeusen
Institute of Tropical Medicine
Co-authored papers 1
Xuliang Jiang
Co-authored papers 1
Geeta J Narlikar
University of California san francisco
Co-authored papers 1
Release 1.2