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Author Details

Maria R Conte
King's College London
1993
58
23
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36690651Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition.Sci Rep2023
37217519AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.Nat Commun2023
37356415LARP4A and LARP4B in cancer: The new kids on the block.Int J Biochem Cell Biol2023
35460669Allosteric Regulation of the Soluble Epoxide Hydrolase by Nitro Fatty Acids: a Combined Experimental and Computational Approach.J Mol Biol2022
32186465Structural dynamics in the La-module of La-related proteins.RNA Biol2021
34124761LARP6C orchestrates posttranscriptional reprogramming of gene expression during hydration to promote pollen tube guidance.Plant Cell2021
31752575The La-related proteins: structures and interactions of a versatile superfamily of RNA-binding proteins.RNA Biol2021
32543856Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α-TAB1 Complexes.J Med Chem2020
32054660Maternal Larp6 controls oocyte development, chorion formation and elevation.Development2020
30632004Resonance assignment of human LARP4A La module.Biomol NMR Assign2019
31660733Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase.Anal Chem2019
30218745Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain.Protein Expr Purif2019
30820564LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.Nucleic Acids Res2019
29229647TAB1-Induced Autoactivation of p38α Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185.Mol Cell Biol2018
28782243The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.Wiley Interdiscip Rev RNA2017
29040270Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins.PLoS One2017
27303796A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry.Acta Crystallogr D Struct Biol2016
27615744The RNA-binding protein LARP4 regulates cancer cell migration and invasion.Cytoskeleton (Hoboken)2016
27782102Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.Nat Commun2016
25488812Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.Nucleic Acids Res2015
25896032(1)H, (15)N and (13)C chemical shift assignments of the La motif and RRM1 from human LARP6.Biomol NMR Assign2015
25415308Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A.PLoS One2014
23148093The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.RNA2013
24037507Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1.Nat Struct Mol Biol2013
22203678RNA chaperone activity of human La protein is mediated by variant RNA recognition motif.J Biol Chem2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
23065565Biosynthetic preparation of 13C/15N-labeled rNTPs for high-resolution NMR studies of RNAs.Methods Mol Biol2012
22009680Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein.Nucleic Acids Res2012
20703834Resonance assignment of nsp7α from arterivirus.Biomol NMR Assign2011
21561912Structure and genetic analysis of the arterivirus nonstructural protein 7alpha.J Virol2011
21658428A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies.Biochimie2011
21098120La-related protein 4 binds poly(A), interacts with the poly(A)-binding protein MLLE domain via a variant PAM2w motif, and can promote mRNA stability.Mol Cell Biol2011
20215441Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.Nucleic Acids Res2010
19760519Letter to the Editor: resonance assignment of SlyD from E. coli.Biomol NMR Assign2009
19619683Getting to the end of RNA: structural analysis of protein recognition of 5' and 3' termini.Biochim Biophys Acta2009
19645725The interaction of the Escherichia coli protein SlyD with nickel ions illuminates the mechanism of regulation of its peptidyl-prolyl isomerase activity.FEBS J2009
18547518Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein.Structure2008
19636881NMR assignment of the N-terminal region of human La free and in complex with RNA.Biomol NMR Assign2008
16584190Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors.Biochemistry2006
16738784Resonance assignment for the N-terminal region of the eukaryotic initiation factor 5 (eIF5).J Biomol NMR2006
16679019A terminal affair: 3'-end recognition by the human La protein.Trends Biochem Sci2006
15004549Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.Nat Struct Mol Biol2004
15213463Resonance assignment and secondary structure of the La motif.J Biomol NMR2004
15341728Structure and RNA interactions of the N-terminal RRM domains of PTB.Structure2004
12842046Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element.Structure2003
12878847Resonance assignment and secondary structure of an N-terminal fragment of the human La protein.J Biomol NMR2003
11788707Chemical shift mapping of RNA interactions with the polypyrimidine tract binding protein.Nucleic Acids Res2002
12018493Resonance assignment and secondary structure determination of a C-terminal fragment of the lupus autoantigen (La) protein containing a putative RNA recognition motif (RRM).J Biomol NMR2002
10856256Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold.EMBO J2000
9657938Retroviral matrix proteins: a structural perspective.Virology1998
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Collaborators

Imperial College London
Co-authored papers 6
University of California San Francisco
Co-authored papers 1
University of Toronto
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
University of Illinois
Co-authored papers 1
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Technische Universitat Munchen (TUM)
Co-authored papers 1
University of Bristol
Co-authored papers 1
The University of Manchester
Co-authored papers 1
Rutgers University
Co-authored papers 1
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
The University of Sheffield
Co-authored papers 1
Institute of Systems, The University of Liverpool
Co-authored papers 1
Institute of Integrative Biology, University of Liverpool
Co-authored papers 1
Columbia University
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
Co-authored papers 1
University of Oxford
Co-authored papers 1
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Institute for Protein Research, Osaka University
Co-authored papers 1
Sichuan University
Co-authored papers 1
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The Francis Crick Institute
Co-authored papers 1
Shinshu University School of Medicine
Co-authored papers 1