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Author Details
Full Name
Roger D Kornberg
Affiliation
Stanford University
ORCID
Career Start Year
1965
Papers
270
H Index
104
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37798444
Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells.
Nat Biomed Eng
2024
36772826
Role of the histone tails in histone octamer transfer.
Nucleic Acids Res
2023
37856313
Combining Force Fields and Neural Networks for an Accurate Representation of Chemically Diverse Molecular Interactions.
J Am Chem Soc
2023
37459529
Class I histone deacetylase complex: Structure and functional correlates.
Proc Natl Acad Sci U S A
2023
37400597
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition.
Nat Chem
2023
36574674
Disruption of nucleosomes by DNA groove binders of clinical significance and implications for chromatin remodeling.
Proc Natl Acad Sci U S A
2023
35338855
Harnessing coronavirus spike proteins' binding affinity to ACE2 receptor through a novel baculovirus surface display system.
Biochem Biophys Res Commun
2022
36459593
Protein-Ligand Binding Free-Energy Calculations with ARROWâ¿¿A Purely First-Principles Parameterized Polarizable Force Field.
J Chem Theory Comput
2022
36417436
Structure of the NuA4 histone acetyltransferase complex.
Proc Natl Acad Sci U S A
2022
35058472
Accurate determination of solvation free energies of neutral organic compounds from first principles.
Nat Commun
2022
34202259
Sub-3 ÿ Cryo-EM Structures of Necrosis Virus Particles via the Use of Multipurpose TEM with Electron Counting Camera.
Int J Mol Sci
2021
33571424
Mediator structure and conformation change.
Mol Cell
2021
33904398
Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator.
Elife
2021
33483974
A Novel AKR1C3 Specific Prodrug TH3424 With Potent Antitumor Activity in Liver Cancer.
Clin Pharmacol Ther
2021
34520722
Structure of mitotic chromosomes.
Mol Cell
2021
34045355
3D genomics across the tree of life reveals condensin II as a determinant of architecture type.
Science
2021
34062386
Gold nanoparticles and tilt pairs to assess protein flexibility by cryo-electron microscopy.
Ultramicroscopy
2021
32763226
Primary Role of the Nucleosome.
Mol Cell
2020
30688648
FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles.
Elife
2019
31150224
IID in 3D: Improved Resolution of Transcription Factor Structure by Cryo-Electron Microscopy.
Biochemistry
2019
30401433
Histone Acetylation Inhibits RSC and Stabilizes the +1 Nucleosome.
Mol Cell
2018
30127031
On the importance of accounting for nuclear quantum effects in ab initio calibrated force fields in biological simulations.
Proc Natl Acad Sci U S A
2018
28635955
Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep
2017
28137832
Chromatin potentiates transcription.
Proc Natl Acad Sci U S A
2017
28300169
Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep
2017
29233217
Chromatin-remodeling for transcription.
Q Rev Biophys
2017
29136369
Structure Determination of a Water-Soluble 144-Gold Atom Particle at Atomic Resolution by Aberration-Corrected Electron Microscopy.
ACS Nano
2017
28765367
Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map.
Proc Natl Acad Sci U S A
2017
27042759
Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size.
Nano Lett
2016
27610567
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell
2016
26073544
Uncoupling Promoter Opening from Start-Site Scanning.
Mol Cell
2015
26544940
Stable Chromosome Condensation Revealed by Chromosome Conformation Capture.
Cell
2015
26331540
Real-time observation of the initiation of RNA polymerase II transcription.
Nature
2015
26483468
Structure of an RNA polymerase II preinitiation complex.
Proc Natl Acad Sci U S A
2015
26537406
Chromatin-remodeling and the initiation of transcription.
Q Rev Biophys
2015
26402457
Molecular architecture of the yeast Mediator complex.
Elife
2015
24733897
Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms.
Proc Natl Acad Sci U S A
2014
25403179
Role of DNA sequence in chromatin remodeling and the formation of nucleosome-free regions.
Genes Dev
2014
25146285
Nanoparticle imaging. Electron microscopy of gold nanoparticles at atomic resolution.
Science
2014
25145777
Israel-Gaza conflict.
Lancet
2014
23000482
RNA polymerase II transcription: structure and mechanism.
Biochim Biophys Acta
2013
24072820
Architecture of an RNA polymerase II transcription pre-initiation complex.
Science
2013
23303183
Formation and fate of a complete 31-protein RNA polymerase II transcription preinitiation complex.
J Biol Chem
2013
22411836
Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.
Proc Natl Acad Sci U S A
2012
23071300
Structure of the mediator head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc Natl Acad Sci U S A
2012
22493230
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.
Proc Natl Acad Sci U S A
2012
22308316
Subunit architecture of general transcription factor TFIIH.
Proc Natl Acad Sci U S A
2012
21319754
Synthesis and characterization of Au102(p-MBA)44 nanoparticles.
J Am Chem Soc
2011
22153066
Lock and key to transcription: Ï¿-DNA interaction.
Cell
2011
21798951
Initiation complex structure and promoter proofreading.
Science
2011
1 - 50 of 270
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