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Author Details

Caroline E Lilley
The Salk Institute for Biological Studies
1996
29
22
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
27512660Critical analysis of an oncolytic herpesvirus encoding granulocyte-macrophage colony stimulating factor for the treatment of malignant melanoma.Oncolytic Virother2014
22405594Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain.Mol Cell2012
21698222The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0.PLoS Pathog2011
21549706Changing the ubiquitin landscape during viral manipulation of the DNA damage response.FEBS Lett2011
19616655Chromatin at the intersection of viral infection and DNA damage.Biochim Biophys Acta2010
21147460Keeping viruses in Chk: DNA damage signaling puts the brakes on transformation.Cell Host Microbe2010
20690823Genomes in conflict: maintaining genome integrity during virus infection.Annu Rev Microbiol2010
20075863A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses.EMBO J2010
19197236Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.EMBO J2009
18854154Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.Cell2008
17275307Using or abusing: viruses and the cellular DNA damage response.Trends Microbiol2007
16630824A hybrid vector for ligand-directed tumor targeting and molecular imaging.Cell2006
16527742APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.Curr Biol2006
15824307DNA repair proteins affect the lifecycle of herpes simplex virus 1.Proc Natl Acad Sci U S A2005
15279805Interactions of viruses with the cellular DNA repair machinery.DNA Repair (Amst)2004
12526157Construction of multiply disabled herpes simplex viral vectors for gene delivery to the nervous system.Methods Mol Med2003
14657032The Mre11 complex is required for ATM activation and the G2/M checkpoint.EMBO J2003
12610151Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: potential of vhs- HSV vectors for dendritic cell-mediated immunotherapy.J Virol2003
11907244A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV genome.J Virol2002
11403416In vivo myocardial gene transfer: optimization, evaluation and direct comparison of gene transfer vectors.Basic Res Cardiol2001
11320412Interruption of coding sequences by heterologous introns can enhance the functional expression of recombinant genes.Gene Ther2001
11287583Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo.J Virol2001
12109061Herpes simplex virus vectors for the nervous system.Curr Gene Ther2001
10823868Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system.J Virol2000
10438830Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects.J Virol1999
9797879Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry.Gene Ther1998
9930311Gene transfer using a disabled herpes virus vector containing the EMCV IRES allows multiple gene expression in vitro and in vivo.Gene Ther1998
9675904Molecular cloning of starch synthase I from maize (W64) endosperm and expression in Escherichia coli.Plant J1998
8723724A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.Genome Res1996
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Sanford Burnham Prebys Medical Discovery Institute
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Rutgers Cancer Institute of New Jersey
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The Ohio State University Wexner Medical Center
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Prestige BioPharma Ltd
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University of California San Francisco
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The University of Texas MD Anderson Cancer Center
Co-authored papers 1
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Stanford University School of Medicine
Co-authored papers 1
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Co-authored papers 1
Institute of Molecular Genetics of the Czech Academy of Sciences
Co-authored papers 1
Genomics Institute of the Novartis Research Foundation
Co-authored papers 1
United States Army Medical Research Institute of Infectious Diseases
Co-authored papers 1
Sanford-Burnham Medical Research Institute
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The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital
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Roche Pharma
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Baylor College of Medicine
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Genomics Institute of the Novartis Research Foundation
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Perelman School of Medicine, University of Pennsylvania
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Merck & Co. Inc.
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TheScripps Research Institute
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Pacific Lutheran University
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