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Author Details

Philippe L Bedard
Princess Margaret Cancer Centre, University Health Network
2002
233
51
PMIDPaper TitleJournal TitlePublished Year
37531083A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors.Oncologist2024
36454580Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases: Updated Exploratory Analysis of the HER2CLIMB Randomized Clinical Trial.JAMA Oncol2023
37865776Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT).J Exp Clin Cancer Res2023
37653066Addressing racial and ethnic disparities in AACR project GENIE.NPJ Precis Oncol2023
37645622Tusamitamab Ravtansine in Patients with Advanced Solid Tumors: Phase I Study of Safety, Pharmacokinetics, and Antitumor Activity Using Alternative Dosing Regimens.Cancer Res Commun2023
37644355The association of cancer-related fatigue on the social, vocational and healthcare-related dimensions of cancer survivorship.J Cancer Surviv2023
37572657A pan-cancer clinical platform to predict immunotherapy outcomes and prioritize immuno-oncology combinations in early-phase trials.Med2023
37768658Anti-TIGIT Antibody Tiragolumab Alone or With Atezolizumab in Patients With Advanced Solid Tumors: A Phase 1a/1b Nonrandomized Controlled Trial.JAMA Oncol2023
37566240Safety, Immunologic, and Clinical Activity of Durvalumab in Combination with Olaparib or Cediranib in Advanced Leiomyosarcoma: Results of the DAPPER Clinical Trial.Clin Cancer Res2023
37419999A tailored phase I-specific patient-reported outcome (PRO) survey to capture the patient experience of symptomatic adverse events.Br J Cancer2023
37341839Symptom screening with Targeted Early Palliative care (STEP) versus usual care for patients with advanced cancer: a mixed methods study.Support Care Cancer2023
37223888The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non-Small Cell Lung Cancer.Clin Cancer Res2023
37027812Tumor-Naïve Circulating Tumor DNA as an Early Response Biomarker for Patients Treated With Immunotherapy in Early Phase Clinical Trials.JCO Precis Oncol2023
36827626Impact of Antibiotic Exposure Before Immune Checkpoint Inhibitor Treatment on Overall Survival in Older Adults With Cancer: A Population-Based Study.J Clin Oncol2023
36670100Longitudinal efficacy and toxicity of SARS-CoV-2 vaccination in cancer patients treated with immunotherapy.Cell Death Dis2023
34623509Novel classes of immunotherapy for breast cancer.Breast Cancer Res Treat2022
35705312Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab.J Immunother Cancer2022
35638085Safety of Minimizing Intensity of Follow-up on Active Surveillance for Clinical Stage I Testicular Germ Cell Tumors.Eur Urol Open Sci2022
35465733A phase III trial of alpelisib + trastuzumab ± fulvestrant versus trastuzumab + chemotherapy in HER2+ <i>PIK3CA</i>-mutated breast cancer.Future Oncol2022
35635640A Phase 2 Trial of Afatinib in Patients with Solid Tumors that Harbor Genomic Aberrations in the HER family: The MOBILITY3 Basket Study.Target Oncol2022
35750695Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies.Nat Commun2022
36636049A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma.J Gastrointest Oncol2022
35939768Phase II Study of Afatinib in Patients With Tumors With Human Epidermal Growth Factor Receptor 2-Activating Mutations: Results From the National Cancer Institute-Molecular Analysis for Therapy Choice ECOG-ACRIN Trial (EAY131) Subprotocol EAY131-B.JCO Precis Oncol2022
35997696Role of Lactate Dehydrogenase in Identifying Relapse for Patients With Stage I Testicular Cancer on Surveillance.J Urol2022
36055464Leveraging big data of immune checkpoint blockade response identifies novel potential targets.Ann Oncol2022
36008705Evaluation of the patient experience of symptomatic adverse events on Phase I clinical trials using PRO-CTCAE.Br J Cancer2022
35192403A Scalable Quality Assurance Process for Curating Oncology Electronic Health Records: The Project GENIE Biopharma Collaborative Approach.JCO Clin Cancer Inform2022
35190802Natural History and Characteristics of ERBB2-mutated Hormone Receptor-positive Metastatic Breast Cancer: A Multi-institutional Retrospective Case-control Study from AACR Project GENIE.Clin Cancer Res2022
35130943Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction.J Exp Clin Cancer Res2022
34918879Semen and serum platinum levels in cisplatin-treated survivors of germ cell cancer.Cancer Med2022
35026412Safety, pharmacokinetics, and antitumor activity of the anti-CEACAM5-DM4 antibody-drug conjugate tusamitamab ravtansine (SAR408701) in patients with advanced solid tumors: first-in-human dose-escalation study.Ann Oncol2022
34931041No evidence of disease versus residual disease in long-term responders to first-line HER2-targeted therapy for metastatic breast cancer.Br J Cancer2022
35337750Comprehensive genomic profiling of treatment resistant metastatic castrate sensitive prostate cancer reveals high frequency of potential therapeutic targets.Clin Genitourin Cancer2022
35264434Phase IB study of ziv-aflibercept plus pembrolizumab in patients with advanced solid tumors.J Immunother Cancer2022
35262412Clinical Application of Next-Generation Sequencing in Advanced Thyroid Cancers.Thyroid2022
35079688Immune checkpoint inhibitor-related myocarditis: an illustrative case series of applying the updated Cardiovascular Magnetic Resonance Lake Louise Criteria.Eur Heart J Case Rep2022
34734967Implications of Selection Bias Due to Delayed Study Entry in Clinical Genomic Studies.JAMA Oncol2022
34582333Use of imaging for active surveillance in testicular cancer: Is real-world practice concordant with guidelines?Can Urol Assoc J2022
32907779Long-term Surveillance of Patients with Complete Response Following Chemotherapy for Metastatic Nonseminomatous Germ Cell Tumor.Eur Urol Oncol2021
33883177Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors.Clin Cancer Res2021
33625877OncoTree: A Cancer Classification System for Precision Oncology.JCO Clin Cancer Inform2021
33507821Long-Term Mental Health Service Utilization Among Survivors of Testicular Cancer: A Population-Based Cohort Study.J Clin Oncol2021
33616650Underreporting of Symptomatic Adverse Events in Phase I Clinical Trials.J Natl Cancer Inst2021
33811119The Future of Clinical Trial Design in Oncology.Cancer Discov2021
33527137The Effect of Metformin vs Placebo on Sex Hormones in Canadian Cancer Trials Group MA.32.J Natl Cancer Inst2021
34492632Phase II Trial of Symptom Screening With Targeted Early Palliative Care for Patients With Advanced Cancer.J Natl Compr Canc Netw2021
34389618First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas.J Immunother Cancer2021
34417144Phase II Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Metastatic Colorectal Cancer.Clin Colorectal Cancer2021
34446728Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.Nat Commun2021
34711609Heterogeneity of Circulating Tumor Cell-Associated Genomic Gains in Breast Cancer and Its Association with the Host Immune Response.Cancer Res2021
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Collaborators

Princess Margaret Cancer Centre, University Ave
Co-authored papers 65
Toronto General Hospital, University Health Network, University of Toronto
Co-authored papers 20
Cancer Clinical Research Unit, Princess Margaret Cancer Centre
Co-authored papers 13
Princess Margaret Cancer Centre
Co-authored papers 12
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 12
Champalimaud Clinical Center/Champalimaud Foundation
Co-authored papers 10
The Princess Margaret Cancer Centre/University of Toronto
Co-authored papers 10
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 10
Co-authored papers 9
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 7
University of Milan
Co-authored papers 7
University of Toronto.
Co-authored papers 7
The First Hospital of Lanzhou University
Co-authored papers 6
Co-authored papers 6
The Kinghorn Cancer Centre, St. Vincent's Hospital Sydney
Co-authored papers 6
Ontario Institute for Cancer Research
Co-authored papers 6
Victoria Hospital
Co-authored papers 6
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Dana-Farber Cancer Institute
Co-authored papers 5
Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Memorial-Sloan Kettering Cancer Center
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Princess Margaret Cancer Centre, University Avenue
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
University Health Network, University of Toronto
Co-authored papers 4
Schulich School of Medicine and Dentistry, University of Western Ontario
Co-authored papers 4
Vanderbilt University Medical Center
Co-authored papers 4
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Co-authored papers 4