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Author Details

Lesley M Forrester
Institute of Regeneration and Repair, The University of Edinburgh
1984
84
38
PMIDPaper TitleJournal TitlePublished Year
37113767Modelling the erythroblastic island niche of dyserythropoietic anaemia type IV patients using induced pluripotent stem cells.Front Cell Dev Biol2023
34088222Resident Macrophages and Their Potential in Cardiac Tissue Engineering.Tissue Eng Part B Rev2022
34405125Progress in the production of haematopoietic stem and progenitor cells from human pluripotent stem cells.J Immunol Regen Med2021
33667414Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System.Stem Cell Reports2021
32169610Alternatively activated macrophages promote resolution of necrosis following acute liver injury.J Hepatol2020
32000892Methods for macrophage differentiation and in vitro generation of human tumor associated-like macrophages.Methods Enzymol2020
32910996The erythroblastic island niche: modeling in health, stress, and disease.Exp Hematol2020
32614947Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs.Blood2020
32364544Production and Characterization of Human Macrophages from Pluripotent Stem Cells.J Vis Exp2020
32171171Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells.Mol Ther Nucleic Acids2020
30930117Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.Cancer Cell2019
30787325Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.Nat Commun2019
29786554A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and <i>in vivo</i> tracking of therapeutic cells.Philos Trans R Soc Lond B Biol Sci2018
30197119Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.Stem Cell Reports2018
28026072Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.Stem Cells2017
28212417SplitAx: A novel method to assess the function of engineered nucleases.PLoS One2017
29303159Erratum: Author Correction: Injection of embryonic stem cell-derived macrophages ameliorates fibrosis in a murine model of liver injury.NPJ Regen Med2017
29302350Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injury.NPJ Regen Med2017
28945231Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm.Nat Cell Biol2017
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
28743878An all-in-one UniSam vector system for efficient gene activation.Sci Rep2017
26996518Concise review: programming human pluripotent stem cells into blood.Br J Haematol2016
27352929Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.Stem Cells Transl Med2016
25752829Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function.Sci Rep2015
26175344A Role for MOSPD1 in Mesenchymal Stem Cell Proliferation and Differentiation.Stem Cells2015
25678556Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.Science2015
23768117SCF/KIT inhibition has a cumulative but reversible effect on the self-renewal of embryonic stem cells and on the survival of differentiating cells.Cell Reprogram2013
24064354Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors.Stem Cell Res2013
23595884Glucocorticoid receptor is required for foetal heart maturation.Hum Mol Genet2013
22084016HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche.Stem Cells2012
22721870Pure populations of murine macrophages from cultured embryonic stem cells. Application to studies of chemotaxis and apoptotic cell clearance.J Immunol Methods2012
22655013Formation of embryoid bodies using dielectrophoresis.Biomicrofluidics2012
22267295Mechanism of action of HOXB4 on the hematopoietic differentiation of embryonic stem cells.Stem Cells2012
20204616The culture of mouse embryonic stem cells and formation of embryoid bodies.Methods Mol Biol2010
20184433Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4.Stem Cells Dev2010
19727443The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.PLoS One2009
19692586Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells.Nucleic Acids Res2009
19591218Balancing work and life: a conversation with Lesley Forrester. Interview by Majlinda Lako and Susan Daher.Stem Cells2009
17803194Aminopeptidase O contains a functional nucleolar localization signal and is implicated in vascular biology.J Cell Biochem2008
18593561Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.Cell Stem Cell2008
17492751A novel triple fusion reporter system for use in gene trap mutagenesis.Genesis2007
16916441A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection.BMC Genomics2006
17142882Deriving and identifying hepatocytes from embryonic stem cells.Stem Cell Rev2006
16820414The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway.J Cell Sci2006
16952354Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment.Exp Cell Res2006
15923657Bone marrow-derived SP cells can contribute to the respiratory tract of mice in vivo.J Cell Sci2005
15456861Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.Mol Cell Biol2004
15533722A novel transmembrane MSP-containing protein that plays a role in right ventricle development.Genomics2004
12806622Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion.Gastroenterology2003
14648851Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.Dev Dyn2003
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Collaborators

University of Edinburgh
Co-authored papers 14
Co-authored papers 3
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University of Oxford
Co-authored papers 3
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 2
Intractable Disease Research Center, Graduate School of Medicine, Juntendo University
Co-authored papers 2
Ochanomizu University
Co-authored papers 2
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology
Co-authored papers 2
RIKEN Center for Integrative Medical Sciences
Co-authored papers 2
RIKEN Center for Integrative Medical Sciences
Co-authored papers 2
University of Twente
Co-authored papers 2
RIKEN Center for Integrative Medical Sciences
Co-authored papers 2
RIKEN Center for Integrative Medical Sciences
Co-authored papers 2
University of Milan
Co-authored papers 2
Karolinska Institute
Co-authored papers 2
Tohoku University Graduate School of Medicine
Co-authored papers 2
Clinic for Plastic, Otto von Guericke University
Co-authored papers 2
University of British Columbia
Co-authored papers 2
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 2
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 2
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 2
Nagoya City University Graduate School of Medical Sciences
Co-authored papers 2
RIKEN Research Center for Allergy and Immunology
Co-authored papers 2
RIKEN Center for Life Science Technologies
Co-authored papers 2
Child and Family Research Institute, University of British Columbia
Co-authored papers 2
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 2
Leiden University Medical Center
Co-authored papers 2
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 2
Yokohama National University
Co-authored papers 2
International Centre for Genetic Engineering and Biotechnology
Co-authored papers 2