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Author Details

Pak C Sham
the University of Hong Kong
1989
770
105
PMIDPaper TitleJournal TitlePublished Year
38086974Correction: Cross-phenotype relationship between opioid use disorder and suicide attempts: new evidence from polygenic association and Mendelian randomization analyses.Mol Psychiatry2024
35164887Ameliorative patterns of grey matter in patients with first-episode and treatment-naïve schizophrenia.Psychol Med2023
37633278Dissecting the high-resolution genetic architecture of complex phenotypes by accurately estimating gene-based conditional heritability.Am J Hum Genet2023
38078747Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case-control study.Psychol Med2023
37602215Inferring CTCF-binding patterns and anchored loops across human tissues and cell types.Patterns (N Y)2023
37292649Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis.medRxiv2023
37061531Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation.Nat Commun2023
37285136Preliminary Evidence for Genetic Nurture in Depression and Neuroticism Through Polygenic Scores.JAMA Psychiatry2023
37211699YBX1-Mediated DNA Methylation-Dependent SHANK3 Expression in PBMCs and Developing Cortical Interneurons in Schizophrenia.Adv Sci (Weinh)2023
37443193Neural variability in three major psychiatric disorders.Mol Psychiatry2023
37310339Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: the EU-GEI study.Psychol Med2023
37441552The genetic basis of onset age in schizophrenia: evidence and models.Front Genet2023
37340172Cross-phenotype relationship between opioid use disorder and suicide attempts: new evidence from polygenic association and Mendelian randomization analyses.Mol Psychiatry2023
37438366Unveiling common psychological characteristics of proneness to aggression and general psychopathology in a large community youth cohort.Transl Psychiatry2023
37129249The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study.Psychol Med2023
37092861Brain transcriptome-wide association study implicates novel risk genes underlying schizophrenia risk.Psychol Med2023
37062770Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis-findings from the EU-GEI study.Mol Psychiatry2023
36889182Functional dysconnectivity of anterior cingulate subregions in schizophrenia and psychotic and nonpsychotic bipolar disorder.Schizophr Res2023
36854672Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data.Nat Commun2023
36746926Common and rare variant associations with latent traits underlying depression, bipolar disorder, and schizophrenia.Transl Psychiatry2023
36711134Third-generation genome sequencing implicates medium-sized structural variants in chronic schizophrenia.Front Neurosci2023
36869052An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping.Nat Commun2023
36709613White matter changes and its relationship with clinical symptom in medication-naive first-episode early onset schizophrenia.Asian J Psychiatr2023
35947471First-Episode Psychosis Patients Who Deteriorated in the Premorbid Period Do Not Have Higher Polygenic Risk Scores Than Others: A Cluster Analysis of EU-GEI Data.Schizophr Bull2023
35076361Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study.Psychol Med2023
35144700Effectiveness and optimal duration of early intervention treatment in adult-onset psychosis: a randomized clinical trial.Psychol Med2023
33032663Evaluation of bi-directional causal association between depression and cardiovascular diseases: a Mendelian randomization study.Psychol Med2022
35652173Clarifying the causes of consistent and inconsistent findings in genetics.Genet Epidemiol2022
35668084Associations between childhood maltreatment and psychiatric disorders: analysis from electronic health records in Hong Kong.Transl Psychiatry2022
35396580Mapping genomic loci implicates genes and synaptic biology in schizophrenia.Nature2022
35527273Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene.BMC Med2022
35750329Improved nonparametric penalized maximum likelihood estimation for arbitrarily censored survival data.Stat Med2022
35779326Extended gene set analysis of human neuro-psychiatric traits shows enrichment in brain-expressed human accelerated regions across development.Schizophr Res2022
36443333Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease.Sci Rep2022
35873260Abnormal Brain Structure Morphology in Early-Onset Schizophrenia.Front Psychiatry2022
36299579Polygenic power calculator: Statistical power and polygenic prediction accuracy of genome-wide association studies of complex traits.Front Genet2022
36380119Discovering the structure and organization of a free Cantonese emotion-label word association graph to understand mental lexicons of emotions.Sci Rep2022
36195640A causal association of ANKRD37 with human hippocampal volume.Mol Psychiatry2022
35093020Mendelian randomization analysis of vitamin D in the secondary prevention of hypertensive-diabetic subjects: role of facilitating blood pressure control.Genes Nutr2022
35211769Striatal dopamine synthesis capacity and its association with negative symptoms upon resolution of positive symptoms in first-episode schizophrenia and delusional disorder.Psychopharmacology (Berl)2022
34872833Structural network alterations and their association with neurological soft signs in schizophrenia: Evidence from clinical patients and unaffected siblings.Schizophr Res2022
35325253Facial Emotion Recognition in Psychosis and Associations With Polygenic Risk for Schizophrenia: Findings From the Multi-Center EU-GEI Case-Control Study.Schizophr Bull2022
34931221Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseases.Nucleic Acids Res2022
35170024Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications.Epilepsia2022
35195259A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.Eur Heart J2022
34570217VannoPortal: multiscale functional annotation of human genetic variants for interrogating molecular mechanism of traits and diseases.Nucleic Acids Res2022
34564762Integrative analysis of metabolomic, genomic, and imaging-based phenotypes identify very-low-density lipoprotein as a potential risk factor for lumbar Modic changes.Eur Spine J2022
34099189Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.Biol Psychiatry2022
34193973Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction.Mol Psychiatry2022
32173736MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes.Cardiovasc Res2021
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Collaborators

David A Collier
Institute of Psychiatry, King's College London
Co-authored papers 68
Paul K H Tam
Queen Mary Hospital, The University of Hong Kong
Co-authored papers 45
You-Qiang Song
The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University
Co-authored papers 38
David Curtis
Co-authored papers 35
Shaun Purcell
Brigham and Women's Hospital
Co-authored papers 30
Peter McGuffin
Co-authored papers 29
Grainne M McAlonan
Institute of Psychiatry, King's College London
Co-authored papers 26
Tai Hing Lam
Co-authored papers 23
Elvira Bramon
Co-authored papers 23
Jo Knight
Data Science Institute and Lancaster University Medical School
Co-authored papers 22
Michael J Owen
Co-authored papers 22
Michael Gill
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Hongsheng Gui
Behavioral Health Services
Co-authored papers 18
Liming Li
Co-authored papers 13
George Kirov
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Kenneth S Kendler
Virginia Commonwealth University
Co-authored papers 12
Benjamin M Neale
Massachusetts General Hospital
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Robert Plomin
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Evangelos Vassos
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Panwen Wang
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Nattiya Hirankarn
Chulalongkorn University
Co-authored papers 11
Anne Farmer
Co-authored papers 11
Michael C O'Donovan
Co-authored papers 10
Hai-Feng Pan
Co-authored papers 9
Jonathan Mill
University of Exeter Medical School, University of Exeter.
Co-authored papers 9
Jacob Shujui Hsu
Graduate Institute of Medical Genomics and Proteomics, National Taiwan University
Co-authored papers 9
Gon??alo R Abecasis
Regeneron Pharmaceuticals Inc.
Co-authored papers 9
Jing Hua Zhao
Co-authored papers 9
Vorasuk Shotelersuk
King Chulalongkorn Memorial Hospital, Chulalongkorn University
Co-authored papers 9
Tim D Spector
King's College London
Co-authored papers 8
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