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Author Details

Julie M Miwa
Lehigh University.
1999
35
21
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36778356Abnormal response to chronic social defeat stress and fear extinction in a mouse model of cholinergic dysregulation.Res Sq2023
37437646Lynx1 and the family of endogenous mammalian neurotoxin-like proteins and their roles in modulating nAChR function.Pharmacol Res2023
36234723Analysis of Protein-Protein Interactions for Intermolecular Bond Prediction.Molecules2022
35813207Editorial: Biology of Ly-6 Supergene Family in Health and Disease.Front Cell Dev Biol2022
33254061Lynx1 prototoxins: critical accessory proteins of neuronal nicotinic acetylcholine receptors.Curr Opin Pharmacol2021
35378834DiffBond: A Method for Predicting Intermolecular Bond Formation.Proceedings (IEEE Int Conf Bioinformatics Biomed)2021
34938964Biophysical characterization of lynx-nicotinic receptor interactions using atomic force microscopy.FASEB Bioadv2021
34803621Differential Expression Patterns of Lynx Proteins and Involvement of Lynx1 in Prepulse Inhibition.Front Behav Neurosci2021
32298703Modulation of cholinergic activity through lynx prototoxins: Implications for cognition and anxiety regulation.Neuropharmacology2020
32208709Dynamics and Interactions of GPI-Linked lynx1 Protein with/without Nicotinic Acetylcholine Receptor in Membrane Bilayers.J Phys Chem B2020
31114495Lynx Prototoxins: Roles of Endogenous Mammalian Neurotoxin-Like Proteins in Modulating Nicotinic Acetylcholine Receptor Function to Influence Complex Biological Processes.Front Pharmacol2019
31247598Neural layer self-assembly in geometrically confined rat and human 3D cultures.Biofabrication2019
29969495Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation.PLoS One2018
28722015TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus.Nat Commun2017
28100642Isoform-specific mechanisms of α3β4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx1.FASEB J2017
29206881Deletion of lynx1 reduces the function of α6* nicotinic receptors.PLoS One2017
25740504Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.J Neurosci2015
25027556Lynx1 supports neuronal health in the mouse dorsal striatum during aging: an ultrastructural investigation.J Mol Neurosci2014
25193667Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum.J Biol Chem2014
22379121Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response.Mol Pharmacol2012
23139735Enhancement in motor learning through genetic manipulation of the Lynx1 gene.PLoS One2012
22771239Psychiatric drugs bind to classical targets within early exocytotic pathways: therapeutic effects.Biol Psychiatry2012
22875450Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction.Physiology (Bethesda)2012
21187334Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning.J Gen Physiol2011
21768117Trafficking of alpha4* nicotinic receptors revealed by superecliptic phluorin: effects of a beta4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine.J Biol Chem2011
21482353Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses.Neuron2011
20660270Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors.J Neurosci2010
21071629Lynx1, a cholinergic brake, limits plasticity in adult visual cortex.Science2010
19246390A role for LYNX2 in anxiety-related behavior.Proc Natl Acad Sci U S A2009
19280351Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.AAPS J2009
18940593In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors.Neuron2008
16950157The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo.Neuron2006
15294139Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo.Neuron2004
11906696Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1.Neuron2002
10402197lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS.Neuron1999
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Collaborators

Nathaniel Heintz
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 7
In??s Iba??ez-Tallon
The Rockefeller University
Co-authored papers 5
Gregg W Crabtree
Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University
Co-authored papers 2
Brian Y Chen
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Alison M Goate
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Anil Bamezai
Villanova University
Co-authored papers 1
Takao K Hensch
Co-authored papers 1
Lorna W Role
National Institute of Neurological Disorders and Stroke (NINDS)
Co-authored papers 1
Heidi C O'Neill
Co-authored papers 1
Roberto Sanchez
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Release 1.2