Skip to Main Content

Author Details

Alain Sewer
Universitat Basel
2005
48
24
Dexter Pratt (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37047398Tobacco Alkaloid Assessment in a DSS-Induced Colitis Mouse Model with a Fully Humanized Immune System.Int J Mol Sci2023
32419906Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke.Comput Struct Biotechnol J2020
31975625A 6-month systems toxicology inhalation study in ApoE<sup>-/-</sup> mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.Am J Physiol Heart Circ Physiol2020
31705857Structural, functional, and molecular impact on the cardiovascular system in ApoE<sup>-/-</sup> mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke.Chem Biol Interact2020
32855621Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.J Inflamm (Lond)2020
33014713A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products.Toxicol Rep2020
32780831Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.Toxicol Sci2020
32123204The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.Sci Rep2020
30686568Corrigendum to "The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product" published in Toxicology in Vitro, Volume 50, August 2018, Pages 95-108.Toxicol In Vitro2019
31494692Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESHâ¿¢ technology.Arch Toxicol2019
30828347Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract.Front Genet2019
30763686A six-month systems toxicology inhalation/cessation study in ApoE<sup>-/-</sup> mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.Food Chem Toxicol2019
30753736How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.ALTEX2019
30610935Assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures.Food Chem Toxicol2019
29505817Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.Food Chem Toxicol2018
29501877Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.Food Chem Toxicol2018
29448087Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes.Food Chem Toxicol2018
29524472The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product.Toxicol In Vitro2018
273886763-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product.ALTEX2017
30090554Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.Toxicol Res (Camb)2017
30090531Systems toxicology meta-analysis of <i>in vitro</i> assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.Toxicol Res (Camb)2017
28620266Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium.Clin Med Insights Circ Respir Pulm Med2017
28025120Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.Food Chem Toxicol2017
27865774A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.Toxicol In Vitro2017
27404394Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures.Chem Res Toxicol2016
27866933Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.Regul Toxicol Pharmacol2016
27117495A framework for in vitro systems toxicology assessment of e-liquids.Toxicol Mech Methods2016
25788831A systems biology approach reveals the dose- and time-dependent effect of primary human airway epithelium tissue culture after exposure to cigarette smoke in vitro.Bioinform Biol Insights2015
26306861Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects.J Proteomics2015
25887162Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems.Database (Oxford)2015
23933191Case study: the role of mechanistic network models in systems toxicology.Drug Discov Today2014
26109882Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model.Interdiscip Toxicol2014
25297719The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure.Int J Toxicol2014
25046638In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.Toxicol Mech Methods2014
25015298Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models.BMC Bioinformatics2014
25113603An algorithm for score aggregation over causal biological networks based on random walk sampling.BMC Res Notes2014
24886675Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression.BMC Res Notes2014
24428674Systems biology approach for evaluating the biological impact of environmental toxicants in vitro.Chem Res Toxicol2014
23355383Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.Am J Physiol Lung Cell Mol Physiol2013
23895370Confero: an integrated contrast data and gene set platform for computational analysis and biological interpretation of omics data.BMC Genomics2013
23933166Quantitative assessment of biological impact using transcriptomic data and mechanistic network models.Toxicol Appl Pharmacol2013
22155224A network-based approach to quantifying the impact of biologically active substances.Drug Discov Today2012
22651900Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks.BMC Syst Biol2012
17459919Marek's disease virus type 2 (MDV-2)-encoded microRNAs show no sequence conservation with those encoded by MDV-1.J Virol2007
17604727A mammalian microRNA expression atlas based on small RNA library sequencing.Cell2007
16971455Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells.Nucleic Acids Res2006
15782219Identification of microRNAs of the herpesvirus family.Nat Methods2005
16274478Identification of clustered microRNAs using an ab initio prediction method.BMC Bioinformatics2005
  • 1 - 48 of 48

Recommended Authors

Jennifer A Aguiar
University of Waterloo
Career Start Year 2017
Number of shared co-authors 0
Chaz Langelier
University of California san francisco
Career Start Year 2015
Number of shared co-authors 0
Chao Jiang
Life Sciences Institute, Zhejiang University
Career Start Year 2015
Number of shared co-authors 0
Yibu Chen
USC Libraries Bioinformatic Services of the University of Southern California
Career Start Year 2012
Number of shared co-authors 0
David Gomez-Cabrero
King Abdullah University of Science and Technology
Career Start Year 2010
Number of shared co-authors 0
Bertrand De Meulder
European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM
Career Start Year 2010
Number of shared co-authors 1
Ting Yang
College of Life Sciences, Sichuan University
Career Start Year 2009
Number of shared co-authors 0
Dejian Zhao
Yale School of Medicine
Career Start Year 2008
Number of shared co-authors 0
Jonathan E Bard
University at Buffalo
Career Start Year 2007
Number of shared co-authors 0
Thomas H Hampton
Geisel School of Medicine, Dartmouth College
Career Start Year 2007
Number of shared co-authors 0
Saskia Trump
Berlin Institute of Health at Charite - Universitatsmedizin Berlin
Career Start Year 2006
Number of shared co-authors 0
Reuben Thomas
Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes
Career Start Year 2004
Number of shared co-authors 0
Susan C Tilton
Oregon State University
Career Start Year 2003
Number of shared co-authors 0
Jette Bornholdt
University of Copenhagen
Career Start Year 2002
Number of shared co-authors 0
Charles J Tucker
National Institute of Environmental Health Sciences, National Institutes of Health
Career Start Year 2002
Number of shared co-authors 0
Hugh D Mitchell
Pacific Northwest National Laboratory (PNNL)
Career Start Year 2002
Number of shared co-authors 0
Alvin T Kho
Brigham and Women's Hospital, Harvard Medical School, Boston Children's Hospital
Career Start Year 2002
Number of shared co-authors 0
Scott S Auerbach
National Institute of Environmental Health Sciences
Career Start Year 2000
Number of shared co-authors 1
David K Crossman
University of Alabama at Birmingham
Career Start Year 2000
Number of shared co-authors 0
Kerby Shedden
University of Michigan ann arbor
Career Start Year 1999
Number of shared co-authors 0
Kristina L Bailey
College of Medicine, University of Nebraska Medical Center
Career Start Year 1997
Number of shared co-authors 0
Avrum Spira
Boston University School of Medicine
Career Start Year 1997
Number of shared co-authors 0
Carole L Yauk
University of Ottawa
Career Start Year 1996
Number of shared co-authors 0
Gary Hardiman
Institute for Global Food Security, Queen's University Belfast
Career Start Year 1994
Number of shared co-authors 0
Maor Sauler
Yale School of Medicine
Career Start Year 1994
Number of shared co-authors 0
Russell D Wolfinger
SAS Institute
Career Start Year 1994
Number of shared co-authors 0
Katrina M Waters
Pacific Northwest National Laboratory
Career Start Year 1994
Number of shared co-authors 1
Hans Gmuender
F. Hoffmann-La Roche Ltd
Career Start Year 1993
Number of shared co-authors 0
Nan Deng
Cedars-Sinai Medical Center
Career Start Year 1992
Number of shared co-authors 0
Jos C S Kleinjans
Maastricht University
Career Start Year 1981
Number of shared co-authors 0

Collaborators

Manuel C Peitsch
Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 42
Julia Hoeng
Vectura Fertin Pharma
Co-authored papers 42
Florian Martin
Co-authored papers 35
Carole Mathis
Johns Hopkins Bayview Medical Center
Co-authored papers 15
Bjoern Titz
university of california los angeles
Co-authored papers 14
Mihaela Zavolan
Co-authored papers 5
Ty M Thomson
FOG Pharmaceuticals Inc.
Co-authored papers 4
Dirk Weisensee
Philip Morris Research Laboratories GmbH
Co-authored papers 3
Stephan Gebel
Co-authored papers 3
Leandro C Hermida
University of Pittsburgh
Co-authored papers 2
Alexei A Aravin
Co-authored papers 2
David A Drubin
Harvard Medical School
Co-authored papers 2
Dexter Pratt (CM4AI)
UC San Diego
Co-authored papers 2
Pablo Landgraf
Co-authored papers 2
Chris Sander
Broad Institute of MIT and Harvard
Co-authored papers 2
Viviana Simon
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Erik van Nimwegen
University of Basel
Co-authored papers 1
Charles M Rice
Rockefeller University
Co-authored papers 1
Christina A Waters
Co-authored papers 1
Renee Deehan
University of California berkeley
Co-authored papers 1
Arndt Borkhardt
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
Co-authored papers 1
Nicholas D Socci
Co-authored papers 1
David de Graaf
Syntimmune Inc.
Co-authored papers 1
Robin Fo??
Sapienza University.
Co-authored papers 1
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers 1
Hans-Rudolf Hotz
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 1
St??phanie Bou??
Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 1
Brett D Lindenbach
Yale University School of Medicine
Co-authored papers 1
Release 1.2