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Author Details

William E Seaman
1974
92
56
PMIDPaper TitleJournal TitlePublished Year
31637878Georgia Abortion Law and Our Commitment to Patients.Arthritis and Rheumatology2020
25995219New blood: Creative funding of disease-specific research.Science Translational Medicine2015
23630120Traumatic brain injury induces macrophage subsets in the brain.European Journal of Immunology2013
21886823Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells.PLoS ONE2011
21036901Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.Journal of Biological Chemistry2011
20200401Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.Journal of Leukocyte Biology2010
20133674Binding and uptake of H-ferritin are mediated by human transferrin receptor-1.Proceedings of the National Academy of Sciences of the United States of America2010
19302484A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia.Journal of Neurochemistry2009
19171755TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.Journal of Cell Biology2009
18411281Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium.Journal of Biological Chemistry2008
19014383Tim-2 is the receptor for H-ferritin on oligodendrocytes.Journal of Neurochemistry2008
18391000The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12.Infect Immun2008
16887962Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.Journal of Immunology2006
16418779TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.Journal of Bone and Mineral Research2006
16945906A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression.Proceedings of the National Academy of Sciences of the United States of America2006
16208663Clinical academic rheumatology: comment on the article by Wickersham et al.2005
16203866TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis.J Exp Med2005
14729615Expression and activation of signal regulatory protein alpha on astrocytomas.Cancer Res2004
15585835Analysis of the major patterns of B cell gene expression changes in response to short-term stimulation with 33 single ligands.J Immunol2004
12847223Pattern recognition by TREM-2: binding of anionic ligands.Journal of Immunology2003
14662855CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation.Journal of Immunology2003
12478301Overview of the Alliance for Cellular Signaling.Nature2002
11754004Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17.European Journal of Immunology2002
11241283Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family.European Journal of Immunology2001
11513135Ligand interactions by activating and inhibitory Ly-49 receptors.Immunological Reviews2001
10857779Natural killer cells and natural killer T cells.2000
10934233Activating Ly-49D and inhibitory Ly-49A natural killer cell receptors demonstrate distinct requirements for interaction with H2-D(d).Journal of Experimental Medicine2000
10528166Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor.Journal of Immunology1999
9927511Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity.Journal of Experimental Medicine1999
9627124Natural killer cells and recognition of MHC class I molecules: new perspectives and challenges in immunology.Scandinavian Journal of Immunology1998
9830044DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase.J Biol Chem1998
9637511The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A.Journal of Immunology1998
9059884Divergent functions of lectin-like receptors on NK cells.Immunological Reviews1997
9034146Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase.J Exp Med1997
8642329An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes.Journal of Experimental Medicine1996
8942069Recognition and signaling by mouse Ly-49 receptors.Chemical Immunology1996
7579199A family of murine NK cell receptors specific for target cell MHC class I molecules.Seminars in Immunology1995
7722466NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity.Journal of Experimental Medicine1995
8046342A natural killer cell receptor specific for a major histocompatibility complex class I molecule.Journal of Experimental Medicine1994
7895167Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain.Immunity1994
8476574The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex.Annual Review of Immunology1993
1506685Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules.Journal of Immunology1992
1346273The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line.Journal of Experimental Medicine1992
1919012NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium.Journal of Immunology1991
1680927cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6.Journal of Immunology1991
1679728Characterization of signal-transducing molecules on natural killer cells.Biochemical Society Transactions1991
1845873Molecular cloning of gp42, a cell-surface molecule that is selectively induced on rat natural killer cells by interleukin 2: glycolipid membrane anchoring and capacity for transmembrane signaling.Journal of Experimental Medicine1991
2033247Divergent regulation of phospholipase C-alpha and phospholipase C-gamma transcripts during activation of a human T cell line.Journal of Immunology1991
2809220Identification and characterization of a cell-surface molecule that is selectively induced on rat lymphokine-activated killer cells.J Immunol1989
2448372Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells.Journal of Immunology1988
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J. Craig Venter Institute
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