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Author Details

Thomas L Fillmore
Pacific Northwest National Laboratory
2011
49
22
PMIDPaper TitleJournal TitlePublished Year
36626706Targeted Mass Spectrometry Assays for Specific Quantification of Urinary proPSA Isoforms.J Proteome Res2023
37760474Validation of a Proteomic Signature of Lung Cancer Risk from Bronchial Specimens of Risk-Stratified Individuals.Cancers (Basel)2023
37502972Decrease in multiple complement protein levels is associated with the development of islet autoimmunity and type 1 diabetes.medRxiv2023
37390828Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity.Cell Rep Med2023
36993277Coupling microdroplet-based sample preparation, multiplexed isobaric labeling, and nanoflow peptide fractionation for deep proteome profiling of tissue microenvironment.bioRxiv2023
36306991A deep redox proteome profiling workflow and its application to skeletal muscle of a Duchenne Muscular Dystrophy model.Free Radic Biol Med2022
34171263The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance.Cancer Cell2021
34182779Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics.mBio2021
34244696Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation.Nat Protoc2021
32532828Detection of Head and Neck Cancer Based on Longitudinal Changes in Serum Protein Abundance.Cancer Epidemiol Biomarkers Prev2020
33425868High-Throughput Large-Scale Targeted Proteomics Assays for Quantifying Pathway Proteins in <i>Pseudomonas putida</i> KT2440.Front Bioeng Biotechnol2020
33298571Amylases in the Human Vagina.mSphere2020
32429558Proteomic Tissue-Based Classifier for Early Prediction of Prostate Cancer Progression.Cancers (Basel)2020
30557009Carrier-Assisted Single-Tube Processing Approach for Targeted Proteomics Analysis of Low Numbers of Mammalian Cells.Anal Chem2019
31241912Automated Nanoflow Two-Dimensional Reversed-Phase Liquid Chromatography System Enables In-Depth Proteome and Phosphoproteome Profiling of Nanoscale Samples.Anal Chem2019
31426316Proteomic Insights into Phycobilisome Degradation, A Selective and Tightly Controlled Process in The Fast-Growing Cyanobacterium <i>Synechococcus elongatus</i> UTEX 2973.Biomolecules2019
31086210A Targeted Mass Spectrometric Assay for Reliable Sensitive Hepcidin Quantification.Sci Rep2019
30525668Rapidly Assessing the Quality of Targeted Proteomics Experiments through Monitoring Stable-Isotope Labeled Standards.J Proteome Res2019
29161511A Customizable Flow Injection System for Automated, High Throughput, and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements.Anal Chem2018
29908079Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.Ann Neurol2018
30226781Increasing the Separation Capacity of Intact Histone Proteoforms Chromatography Coupling Online Weak Cation Exchange-HILIC to Reversed Phase LC UVPD-HRMS.J Proteome Res2018
30087585Residual tissue repositories as a resource for population-based cancer proteomic studies.Clin Proteomics2018
30271983Facile carrier-assisted targeted mass spectrometric approach for proteomic analysis of low numbers of mammalian cells.Commun Biol2018
29584399Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway.Anal Chem2018
28634240Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in <i>Yarrowia lipolytica</i>.mBio2017
28245256Effects of delayed NSAID administration after experimental eccentric contraction injury - A cellular and proteomics study.PLoS One2017
29254211Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins.Oncotarget2017
28810879Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics.J Transl Med2017
28724286Deep-Dive Targeted Quantification for Ultrasensitive Analysis of Proteins in Nondepleted Human Blood Plasma/Serum and Tissues.Anal Chem2017
28722704Targeted proteomic assays for quantitation of proteins identified by proteogenomic analysis of ovarian cancer.Sci Data2017
27028594Capillary Electrophoresis-Nanoelectrospray Ionization-Selected Reaction Monitoring Mass Spectrometry via a True Sheathless Metal-Coated Emitter Interface for Robust and High-Sensitivity Sample Quantification.Anal Chem2016
27165815Mining the human urine proteome for monitoring renal transplant injury.Kidney Int2016
25350482Comprehensive quantitative analysis of ovarian and breast cancer tumor peptidomes.J Proteome Res2015
26107611Orthogonal Injection Ion Funnel Interface Providing Enhanced Performance for Selected Reaction Monitoring-Triple Quadrupole Mass Spectrometry.Anal Chem2015
25889691Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods.J Transl Med2015
25965799Proteomic analysis reveals down-regulation of surfactant protein B in murine type II pneumocytes infected with influenza A virus.Virology2015
25517423Sensitive targeted quantification of ERK phosphorylation dynamics and stoichiometry in human cells without affinity enrichment.Anal Chem2015
24251762A highly sensitive targeted mass spectrometric assay for quantification of AGR2 protein in human urine and serum.J Proteome Res2014
25192788Microscale depletion of high abundance proteins in human biofluids using IgY14 immunoaffinity resin: analysis of human plasma and cerebrospinal fluid.Anal Bioanal Chem2014
25266362Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer.Mol Oncol2014
25145539Expediting SRM assay development for large-scale targeted proteomics experiments.J Proteome Res2014
24881670GlyQ-IQ: glycomics quintavariate-informed quantification with high-performance computing and GlycoGrid 4D visualization.Anal Chem2014
23277452Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes.J Exp Med2013
24004026Long-gradient separations coupled with selected reaction monitoring for highly sensitive, large scale targeted protein quantification in a single analysis.Anal Chem2013
23763644Targeted quantification of low ng/mL level proteins in human serum without immunoaffinity depletion.J Proteome Res2013
22354571A reversed-phase capillary ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method for comprehensive top-down/bottom-up lipid profiling.Anal Bioanal Chem2012
22949669Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum.Proc Natl Acad Sci U S A2012
22846433Analysis of serum total and free PSA using immunoaffinity depletion coupled to SRM: correlation with clinical immunoassay tests.J Proteomics2012
2198877718O-labeled proteome reference as global internal standards for targeted quantification by selected reaction monitoring-mass spectrometry.Mol Cell Proteomics2011
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Collaborators

Richard D Smith
Pacific Northwest National Laboratory
Co-authored papers 34
Tao Liu
Pacific Northwest National Laboratory
Co-authored papers 27
Tujin Shi
Pacific Northwest National Laboratory
Co-authored papers 26
Wei-Jun Qian
Co-authored papers 24
Karin D Rodland
Oregon Health and Science University
Co-authored papers 21
Athena A Schepmoes
Pacific Northwest National Laboratory
Co-authored papers 19
Yuqian Gao
Co-authored papers 19
Ronald J Moore
Co-authored papers 17
David G Camp
Co-authored papers 13
Rui Zhao
Co-authored papers 11
Marina A Gritsenko
Pacific Northwest National Laboratory
Co-authored papers 11
Sudhir Srivastava
National Cancer Institute
Co-authored papers 9
Thomas O Metz
Pacific Northwest National Laboratory
Co-authored papers 9
Paul D Piehowski
Pacific Northwest National Laboratory
Co-authored papers 9
Bobbie-Jo M Webb-Robertson
Pacific Northwest National Laboratory
Co-authored papers 8
Chaochao Wu
Co-authored papers 7
Vladislav A Petyuk
Pacific Northwest National Laboratory
Co-authored papers 5
Daniel J Orton
Co-authored papers 5
H S Wiley
Co-authored papers 4
Therese R W Clauss
Pacific Northwest National Laboratory
Co-authored papers 4
Rosalie K Chu
Co-authored papers 4
Jon M Jacobs
Pacific Northwest National Laboratory
Co-authored papers 4
Ernesto S Nakayasu
Co-authored papers 4
Robin J Leach
University of Texas Health San Antonio
Co-authored papers 3
Karl K Weitz
Pacific Northwest National Laboratory
Co-authored papers 3
Anil K Shukla
Pacific Northwest National Laboratory
Co-authored papers 3
Samuel H Payne
Brigham Young University
Co-authored papers 3
Matthew E Monroe
Pacific Northwest National Laboratory
Co-authored papers 3
Charles Ansong
Pacific Northwest National Laboratory
Co-authored papers 3
Yi-Ting Wang
McGill Research Centre for Studies in Aging
Co-authored papers 3
Release 1.2