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Author Details

Kyle M Miller
The University of Texas at Austin
2001
67
38
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35331626Histone H2A variants: Diversifying chromatin to ensure genome integrity.Semin Cell Dev Biol2023
36983041Clinical and Mechanistic Implications of R-Loops in Human Leukemias.Int J Mol Sci2023
37070200A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis.Nucleic Acids Res2023
36255636Single-Cell Analysis of Histone Acetylation Dynamics at Replication Forks Using PLA and SIRF.Methods Mol Biol2023
35253893ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination.Nucleic Acids Res2022
35532219Joining the PARty: PARP Regulation of KDM5A during DNA Repair (and Transcription?).Bioessays2022
36265488RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA.Mol Cell2022
33279952Emerging roles of RNA modifications in genome integrity.Brief Funct Genomics2021
34548613Bromodomain proteins: protectors against endogenous DNA damage and facilitators of genome integrity.Exp Mol Med2021
34659365Making Connections: Integrative Signaling Mechanisms Coordinate DNA Break Repair in Chromatin.Front Genet2021
33941775DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.Nat Commun2021
34003252Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions.J Cell Biol2021
30620620FKBP25 participates in DNA double-strand break repair.Biochem Cell Biol2020
32808652Making it or breaking it: DNA methylation and genome integrity.Essays Biochem2020
32966758PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.Mol Cell2020
32675241Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.Proc Natl Acad Sci U S A2020
30652105Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways.Microb Cell2019
31753913Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.Genes Dev2019
31395347Histone methylation and the DNA damage response.Mutat Res Rev Mutat Res2019
31331819Non-canonical DNA/RNA structures during Transcription-Coupled Double-Strand Break Repair: Roadblocks or Bona fide repair intermediates?DNA Repair (Amst)2019
31127569In Time and Space: Laser Microirradiation and the DNA Damage Response.Methods Mol Biol2019
31164001Preserving genome integrity and function: the DNA damage response and histone modifications.Crit Rev Biochem Mol Biol2019
29370947Caught with One's Zinc Fingers in the Genome Integrity Cookie Jar.Trends Genet2018
30073532CRISPR/Cas9 Gene Editing of Human Histone H2A Variant H2AX and MacroH2A.Methods Mol Biol2018
30523780Sae2/CtIP prevents R-loop accumulation in eukaryotic cells.Elife2018
30268364Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells.DNA Repair (Amst)2018
30393775Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.Commun Biol2018
30388705KDM5A Regulates a Translational Program that Controls p53 Protein Expression.iScience2018
29393731Double duty: ZMYND8 in the DNA damage response and cancer.Cell Cycle2018
28847823Bromodomain proteins: repairing DNA damage within chromatin.Philos Trans R Soc Lond B Biol Sci2017
28474855Chromatin Regulates Genome Targeting with Cisplatin.Angew Chem Int Ed Engl2017
28242625ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.Genes Dev2017
28572115Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.J Cell Biol2017
27006338Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients.EMBO Mol Med2016
27631103Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer.PLoS Genet2016
27240007The nucleosome: orchestrating DNA damage signaling and repair within chromatin.Biochem Cell Biol2016
26884156Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins.Proc Natl Acad Sci U S A2016
25593309Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.Genes Dev2015
26508657Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.EMBO Rep2015
26030852ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion.Elife2015
25642960Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.Nature2015
24658350Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.Nat Struct Mol Biol2014
25311424Unravelling the genomic targets of small molecules using high-throughput sequencing.Nat Rev Genet2014
24603765Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling.PLoS Genet2014
23109425Systematic identification of functional residues in mammalian histone H2AX.Mol Cell Biol2013
24171103Engineered proteins detect spontaneous DNA breakage in human and bacterial cells.Elife2013
23927873Mammalian DNA repair: HATs and HDACs make their mark through histone acetylation.Mutat Res2013
22306580Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.Nat Chem Biol2012
22435814Histone marks: repairing DNA breaks within the context of chromatin.Biochem Soc Trans2012
22115396G-quadruplexes: selective DNA targeting for cancer therapeutics?Expert Rev Clin Pharmacol2011
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Collaborators

Mission Therapeutics Ltd. Glenn Berge Building
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CNRS, Universite de Toulouse
Co-authored papers 5
University of Texas at Austin
Co-authored papers 4
University of California San Francisco
Co-authored papers 3
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Co-authored papers 3
University of North Carolina
Co-authored papers 2
Stanford University
Co-authored papers 2
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Co-authored papers 2
Memorial Sloan-Kettering Cancer Center
Co-authored papers 2
The Weizmann Institute of Science
Co-authored papers 1
University of California davis
Co-authored papers 1
Jeonbuk National University
Co-authored papers 1
MNM Bioscience Inc.
Co-authored papers 1
Institute for Cancer Genetics, Columbia University Irving Medical Center
Co-authored papers 1
University of Toronto
Co-authored papers 1
Ludwig Institute for Cancer Research San Diego Branch
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
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Brandeis University
Co-authored papers 1
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University of Toronto
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National Institute of Environmental Health Sciences (NIEHS)
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West China Hospital, Sichuan University
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Boston University School of Medicine, Boston University
Co-authored papers 1
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Counsyl Inc.
Co-authored papers 1
St. Jude Children's Research Hospital
Co-authored papers 1