|
| 36670186 | Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes. | Commun Med (Lond) | 2023 |
| 37949472 | Ethnic disparities in progression rates for sight-threatening diabetic retinopathy in diabetic eye screening: a population-based retrospective cohort study. | BMJ Open Diabetes Res Care | 2023 |
| 37657941 | Exploring the Role of Plasma Lipids and Statin Interventions on Multiple Sclerosis Risk and Severity: A Mendelian Randomization Study. | | 2023 |
| 37997097 | The impact of risk stratification by polygenic risk and age on breast cancer screening in women aged 40-49 years: a modelling study. | | 2023 |
| 37645746 | Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders. | | 2023 |
| 37986811 | NMR metabolomic modelling of age and lifespan: a multi-cohort analysis. | medRxiv | 2023 |
| 37859783 | Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog. | | 2023 |
| 37770635 | Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification. | Nat Genet | 2023 |
| 37034659 | Proteogenomic integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis. | medRxiv | 2023 |
| 36716318 | Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study. | PLoS Med | 2023 |
| 37464031 | Biological and functional multimorbidity-from mechanisms to management. | | 2023 |
| 37126556 | Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity. | Sci Adv | 2023 |
| 37313748 | How to assess pharmacogenomic tests for implementation in the NHS in England. | | 2023 |
| 37310738 | Estimating Dementia Risk Using Multifactorial Prediction Models. | | 2023 |
| 37178708 | Utility of polygenic risk scores in UK cancer screening: a modelling analysis. | Lancet Oncol | 2023 |
| 36460578 | Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. | Lancet Digit Health | 2023 |
| 36854461 | Realistic expectations are key to realising the benefits of polygenic scores. | BMJ | 2023 |
| 34815331 | Cochrane corner: PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease. | Heart | 2022 |
| 35699621 | Immune boosting by B.1.1.529 <b>(</b>Omicron) depends on previous SARS-CoV-2 exposure. | Science | 2022 |
| 35381005 | Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank. | PLoS One | 2022 |
| 35692035 | Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants. | BMC Med | 2022 |
| 35432461 | LDL-C Concentrations and the 12-SNP LDL-C Score for Polygenic Hypercholesterolaemia in Self-Reported South Asian, Black and Caribbean Participants of the UK Biobank. | Frontiers in Genetics | 2022 |
| 35681241 | Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study. | Cardiovasc Diabetol | 2022 |
| 35796550 | The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study. | Hum Mol Genet | 2022 |
| 36197964 | Comment on "A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk". | Science Translational Medicine | 2022 |
| 35921096 | Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease: A Factorial Mendelian Randomization Study. | JAMA Cardiology | 2022 |
| 36315950 | Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation : A Multinational Population-Based Cohort Study. | Ann Intern Med | 2022 |
| 37118290 | Immune system-wide Mendelian randomization and triangulation analyses support autoimmunity as a modifiable component in dementia-causing diseases. | Nat Aging | 2022 |
| 34338426 | Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies. | Alzheimers Dement | 2022 |
| 35300523 | Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization. | Circulation | 2022 |
| 35308936 | Mapping the Read2/CTV3 controlled clinical terminologies to Phecodes in UK Biobank primary care electronic health records: implementation and evaluation. | AMIA Annu Symp Proc | 2022 |
| 35259281 | Biological mechanisms of aging predict age-related disease co-occurrence in patients. | Aging Cell | 2022 |
| 34649961 | Human Genomics and Drug Development. | Cold Spring Harbor Perspectives in Medicine | 2022 |
| 34930919 | Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome. | Nat Commun | 2021 |
| 34286063 | Adult height and incidence of atrial fibrillation and heart failure in older men: The British Regional Heart Study. | IJC Heart and Vasculature | 2021 |
| 33958779 | Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney. | Nat Genet | 2021 |
| 33536532 | Data-driven identification of ageing-related diseases from electronic health records. | Sci Rep | 2021 |
| 33531486 | Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection. | Nat Commun | 2021 |
| 33679875 | No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis. | Frontiers in Genetics | 2021 |
| 33526857 | Correction: Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory. | International Journal of Obesity | 2021 |
| 34107730 | Remote Ischemic Preconditioning Protects Against Endothelial Dysfunction in a Human Model of Systemic Inflammation: A Randomized Clinical Trial. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2021 |
| 33517400 | Genome-wide association study of circulating interleukin 6 levels identifies novel loci. | Hum Mol Genet | 2021 |
| 33446837 | Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory. | International Journal of Obesity | 2021 |
| 34095633 | Selective Interleukin-6 Trans-Signaling Blockade Is More Effective Than Panantagonism in Reperfused Myocardial Infarction. | JACC: Basic to Translational Science | 2021 |
| 33558525 | Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. | Nat Commun | 2021 |
| 32936666 | Establishing reference intervals for triglyceride-containing lipoprotein subfraction metabolites measured using nuclear magnetic resonance spectroscopy in a UK population. | Annals of Clinical Biochemistry | 2021 |
| 32678345 | Probability of encountering Covid-19 patients based on prevalence and testing during resumption of ophthalmology services. | Eye | 2021 |
| 33221853 | Metabolic profiles of socio-economic position: a multi-cohort analysis. | Int J Epidemiol | 2021 |
| 33402679 | Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. | Nat Commun | 2021 |
| 34734970 | Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration: A Mendelian Randomization Study. | JAMA Ophthalmol | 2021 |