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Author Details
Full Name
Lei S Qi
Affiliation
Stanford University
ORCID
Career Start Year
2008
Papers
100
H Index
47
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36280707
Advances in CRISPR therapeutics.
Nat Rev Nephrol
2023
37550295
Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing.
Nat Commun
2023
37127707
Stable expression of large transgenes via the knock-in of an integrase-deficient lentivirus.
Nat Biomed Eng
2023
36855120
Nanoscale, antigen encounter-dependent, IL-12 delivery by CAR T cells plus PD-L1 blockade for cancer treatment.
J Transl Med
2023
36736311
Reversing the Central Dogma: RNA-guided control of DNA in epigenetics and genome editing.
Mol Cell
2023
34127974
Multi-color super-resolution imaging to study human coronavirus RNA during cellular infection.
bioRxiv
2022
35618183
Hormone sensitive lipase ablation promotes bone regeneration.
Biochim Biophys Acta Mol Basis Dis
2022
35637351
Scalable biological signal recording in mammalian cells using Cas12a base editors.
Nat Chem Biol
2022
35758824
Enhanced Myogenesis by Silencing Myostatin with Nonviral Delivery of a dCas9 Ribonucleoprotein Complex.
CRISPR J
2022
35589813
Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro.
Nat Commun
2022
35414015
Multiplexed genome regulation in vivo with hyper-efficient Cas12a.
Nat Cell Biol
2022
37214176
High-content CRISPR screening.
Nat Rev Methods Primers
2022
36543165
SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D.
Cell Rep
2022
35926435
Corrigendum to "Hormone sensitive lipase ablation promotes bone regeneration" [Biochim. Biophys. Acta Mol. Basis Dis. Volume 1868, Issue 9, 1 September 2022, 166449].
Biochim Biophys Acta Mol Basis Dis
2022
35952672
Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes.
Neuron
2022
35951677
Nested epistasis enhancer networks for robust genome regulation.
Science
2022
35981511
What are the current bottlenecks in developing and applying CRISPR technologies?
Cell Syst
2022
35130925
Dual CRISPR interference and activation for targeted reactivation of X-linked endogenous FOXP3 in human breast cancer cells.
Mol Cancer
2022
35128513
Multi-color super-resolution imaging to study human coronavirus RNA during cellular infection.
Cell Rep Methods
2022
35145236
The use of new CRISPR tools in cardiovascular research and medicine.
Nat Rev Cardiol
2022
35271371
CRISPR-Mediated Synergistic Epigenetic and Transcriptional Control.
CRISPR J
2022
33420494
CRISPR technologies for precise epigenome editing.
Nat Cell Biol
2021
37849948
Durable CRISPR-Based Epigenetic Silencing.
Biodes Res
2021
33545038
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Cell
2021
33893274
CRISPR-based genome editing in primary human pancreatic islet cells.
Nat Commun
2021
33558716
Engineering 3D genome organization.
Nat Rev Genet
2021
33778788
A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses.
Cell Rep Med
2021
34499031
Enhanced Cas12a multi-gene regulation using a CRISPR array separator.
Elife
2021
34428454
Interrogation of the dynamic properties of higher-order heterochromatin using CRISPR-dCas9.
Mol Cell
2021
34480847
Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing.
Mol Cell
2021
34743703
Contextual reprogramming of CAR-T cells for treatment of HER2<sup>+</sup> cancers.
J Transl Med
2021
34302664
CRISPRi/a Screening with Human iPSCs.
Methods Mol Biol
2021
34337559
Single-cell transcriptomic profiling reveals distinct mechanical responses between normal and diseased tendon progenitor cells.
Cell Rep Med
2021
32092381
Therapeutic genome editing in cardiovascular diseases.
Adv Drug Deliv Rev
2021
32430322
Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites.
Proc Natl Acad Sci U S A
2020
32027839
Multiple Input Sensing and Signal Integration Using a Split Cas12a System.
Mol Cell
2020
33346712
Regenerating Urethral Striated Muscle by CRISPRi/dCas9-KRAB-Mediated Myostatin Silencing for Obesity-Associated Stress Urinary Incontinence.
CRISPR J
2020
32967676
Lentiviral delivery of combinatorial CAR/CRISPRi circuit into human primary T cells is enhanced by TBK1/IKKÉ¿ complex inhibitor BX795.
J Transl Med
2020
32900183
Double Emulsion Picoreactors for High-Throughput Single-Cell Encapsulation and Phenotyping via FACS.
Anal Chem
2020
32151271
A benchmark of algorithms for the analysis of pooled CRISPR screens.
Genome Biol
2020
32210226
Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells.
Nat Commun
2020
32205365
Fibrinogen Alpha Chain Knockout Promotes Tumor Growth and Metastasis through Integrin-AKT Signaling Pathway in Lung Cancer.
Mol Cancer Res
2020
32353252
Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.
Cell
2020
30643127
Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells.
Nat Commun
2019
37850090
Biodesign Research to Advance the Principles and Applications of Biosystems Design.
Biodes Res
2019
31748579
Identification of cell context-dependent YAP-associated proteins reveals β<sub>1</sub> and β<sub>4</sub> integrin mediate YAP translocation independently of cell spreading.
Sci Rep
2019
29958882
A CRISPR-dCas Toolbox for Genetic Engineering and Synthetic Biology.
J Mol Biol
2019
31348878
Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems.
Mol Cell
2019
31488703
CRISPR-mediated live imaging of genome editing and transcription.
Science
2019
31015465
YAP-independent mechanotransduction drives breast cancer progression.
Nat Commun
2019
1 - 50 of 100
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