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Author Details

Ake T Lu
David Geffen School of Medicine
2001
83
34
PMIDPaper TitleJournal TitlePublished Year
37369886Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1.Geroscience2024
36865294Higher testosterone and testosterone/estradiol ratio in men are associated with better epigenetic estimators of mortality risk.medRxiv2023
37561875DNA methylation networks underlying mammalian traits.Science2023
37594403Bloom syndrome patients and mice display accelerated epigenetic aging.Aging Cell2023
37500973Multi-omic rejuvenation and life span extension on exposure to youthful circulation.Nat Aging2023
37493860Pan-primate studies of age and sex.Geroscience2023
37325994Early life adversity predicts an accelerated cellular aging phenotype through early timing of puberty.Psychol Med2023
36964402Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity.Geroscience2023
36994812DNA methylation-based biomarkers for ageing long-lived cetaceans.Mol Ecol Resour2023
36855161Refining epigenetic prediction of chronological and biological age.Genome Med2023
36622282Alcohol consumption and epigenetic age acceleration in young adults.Aging (Albany NY)2023
36812475DNAmFitAge: biological age indicator incorporating physical fitness.Aging (Albany NY)2023
36435663Corrigendum to "Association of subjective social status with epigenetic aging among Black and White women" [Psychoneuroendocrinology, 141 (2022), 105748].Psychoneuroendocrinology2023
35145108A mammalian methylation array for profiling methylation levels at conserved sequences.Nat Commun2022
35580182DNA methylation clocks for dogs and humans.Proc Natl Acad Sci U S A2022
35346416Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study.Elife2022
35397259Association of subjective social status with epigenetic aging among Black and White women.Psychoneuroendocrinology2022
35389339Genetic loci and metabolic states associated with murine epigenetic aging.Elife2022
36516495DNA methylation GrimAge version 2.Aging (Albany NY)2022
36280888Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies.Genome Biol2022
36071115Author Correction: DNA methylation predicts age and provides insight into exceptional longevity of bats.Nat Commun2022
36289503Marijuana use and DNA methylation-based biological age in young adults.Clin Epigenetics2022
36052758Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers.Aging Cell2022
35039495Epigenetic aging of the demographically non-aging naked mole-rat.Nat Commun2022
33211845GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality.J Gerontol A Biol Sci Med Sci2021
33795458Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons.Science2021
33712580DNA methylation predicts age and provides insight into exceptional longevity of bats.Nat Commun2021
34887417Meta-analyses identify DNA methylation associated with kidney function and damage.Nat Commun2021
34887389Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.Nat Commun2021
34587750Epigenetic Age and the Risk of Incident Atrial Fibrillation.Circulation2021
34428927Epigenetic Age Acceleration Reflects Long-Term Cardiovascular Health.Circ Res2021
34482522DNA methylation age analysis of rapamycin in common marmosets.Geroscience2021
34768133DNA methylation-based surrogates of plasma proteins are associated with Parkinson's disease risk.J Neurol Sci2021
34078457DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function.Clin Epigenetics2021
34059764Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins.Commun Biol2021
33953189Author Correction: DNA methylation predicts age and provides insight into exceptional longevity of bats.Nat Commun2021
34050697Clonal hematopoiesis associated with epigenetic aging and clinical outcomes.Aging Cell2021
32697766Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals.Aging (Albany NY)2020
31985870Coagulation factor VIII: Relationship to cardiovascular disease risk and whole genome sequence and epigenome-wide analysis in African Americans.J Thromb Haemost2020
32913184DNA methylation study of Huntington's disease and motor progression in patients and in animal models.Nat Commun2020
32991324Epigenetic mutation load is weakly correlated with epigenetic age acceleration.Aging (Albany NY)2020
30669119DNA methylation GrimAge strongly predicts lifespan and healthspan.Aging (Albany NY)2019
31235674Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels.Aging (Albany NY)2019
31461406Epigenome-wide association study of leukocyte telomere length.Aging (Albany NY)2019
31422385DNA methylation-based estimator of telomere length.Aging (Albany NY)2019
31136303Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation.Aging (Albany NY)2019
30958317Longitudinal Epigenome-Wide Methylation Study of Cognitive Decline and Motor Progression in Parkinson's Disease.J Parkinsons Dis2019
29676998An epigenetic biomarker of aging for lifespan and healthspan.Aging (Albany NY)2018
30048243Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and <i>ex vivo</i> studies.Aging (Albany NY)2018
29374233GWAS of epigenetic aging rates in blood reveals a critical role for TERT.Nat Commun2018
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Collaborators

David Geffen School of Medicine, University of California los angeles
Co-authored papers 44
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National Institute on Aging, National Institutes of Health
Co-authored papers 13
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Institute of Genetics and Cancer, University of Edinburgh
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Mailman School of Public Health, Columbia University
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Casey Eye Institute, Oregon Health & Science University
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and Blood Institute, National Institutes of Health
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University of British Columbia
Co-authored papers 7
Beth Israel Deaconess Medical Center
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University of Mississippi Medical Center
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Kaiser Permanente Research Bank
Co-authored papers 6
Laboratory of Clinical Epidemiology
Co-authored papers 6
Southern California Eye Institute, CHA Hollywood Presbyterian Medical Center
Co-authored papers 5
Ludwig-Maximilians-Universitat Munchen
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Casey Eye Institute, Oregon Health & Science University
Co-authored papers 5
Feinberg School of Medicine, Northwestern University
Co-authored papers 5
Boston University School of Medicine
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King's College London
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German Research Center for Cardiovascular Disease (DZHK)
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National Institute on Aging, National Institutes of Health
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Brigham and Women's Hospital
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