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Author Details

Stuart Aitken
Queensland Children's Hospital
1982
44
18
PMIDPaper TitleJournal TitlePublished Year
3694021511β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis.PLoS One2023
35759651Fostering Gender-IQ: Barriers and Enablers to Gender-affirming Behavior Amongst an Australian General Practitioner Cohort.J Homosex2023
36561149IMPROVE-DD: Integrating multiple phenotype resources optimizes variant evaluation in genetically determined developmental disorders.HGG Adv2022
35768279A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation.RNA2022
35589755RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer.Nat Commun2022
34338635Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function.Elife2021
33879799RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways.Nat Commun2021
30988016A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes.EMBO J2019
31615982Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1.Nat Commun2019
29323667Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1,133 families with developmental disorders.Genet Med2018
30089658Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli.Open Biol2018
28345629WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel.Sci Rep2017
28289143Transcription factor Wilms' tumor 1 regulates developmental RNAs through 3' UTR interaction.Genes Dev2017
28468917The circadian dynamics of small nucleolar RNA in the mouse liver.J R Soc Interface2017
25614342Patient satisfaction from two studies of collaborative doctor-pharmacist prescribing in Australia.Health Expect2016
27417972Bioinformatic Analysis of Next-Generation Sequencing Data to Identify WT1-Associated Differential Gene and Isoform Expression.Methods Mol Biol2016
25637558Dizzy-Beats: a Bayesian evidence analysis tool for systems biology.Bioinformatics2015
26700852Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.Mol Syst Biol2015
25885578Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response.PLoS Comput Biol2015
26013771Integrative modeling reveals the principles of multi-scale chromatin boundary formation in human nuclear organization.Genome Biol2015
24931999Stochastic EM-based TFBS motif discovery with MITSU.Bioinformatics2014
25200078Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution.Nucleic Acids Res2014
23806098MCOIN: a novel heuristic for determining transcription factor binding site motif width.Algorithms Mol Biol2013
23899119Nested sampling for parameter inference in systems biology: application to an exemplar circadian model.BMC Syst Biol2013
23804443A rule-based kinetic model of RNA polymerase II C-terminal domain phosphorylation.J R Soc Interface2013
22533924EnzML: multi-label prediction of enzyme classes using InterPro signatures.BMC Bioinformatics2012
21388572Mapping between the OBO and OWL ontology languages.J Biomed Semantics2011
22022255Modelling reveals kinetic advantages of co-transcriptional splicing.PLoS Comput Biol2011
21624952Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation.J Cell Biol2011
20126621Processivity and coupling in messenger RNA transcription.PLoS One2010
18056066OBO Explorer: an editor for Open Biomedical Ontologies in OWL.Bioinformatics2008
18773494A bioinformatics approach for identifying candidate transcriptional regulators of mesenchyme-to-epithelium transitions in mouse embryos.Dev Dyn2008
17074078Mining housekeeping genes with a Naive Bayes classifier.BMC Genomics2006
15513995COBrA: a bio-ontology editor.Bioinformatics2005
15958165Feature selection and classification for microarray data analysis: evolutionary methods for identifying predictive genes.BMC Bioinformatics2005
15797906Formalizing concepts of species, sex and developmental stage in anatomical ontologies.Bioinformatics2005
14992501Part-of relations in anatomy ontologies: a proposal for RDFS and OWL formalisations.Pac Symp Biocomput2004
18629134The SOFG Anatomy Entry List (SAEL): an annotation tool for functional genomics data.Comp Funct Genomics2004
1346876Immunogenicity of combined diphtheria, tetanus, and pertussis vaccine given at 2, 3, and 4 months versus 3, 5, and 9 months of age.Lancet1992
1351207Diphtheria, pertussis, and tetanus vaccination.Lancet1992
1580674Immunogenicity and safety of PRP-T conjugate vaccine given according to the British accelerated immunisation schedule.Arch Dis Child1992
2975334Computer-aided instruction with the multiply impaired.J Ment Defic Res1988
6874246Developmental aspects of sensory substitution.Int J Neurosci1983
7069369Intersensory substitution in the blind.J Exp Child Psychol1982
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Collaborators

Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Center for Integrative Medical Sciences
Co-authored papers 3
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Co-authored papers 3
Co-authored papers 3
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Wellcome Sanger Institute
Co-authored papers 2
Institute for Language, University of Edinburgh.
Co-authored papers 2
Illumina Cambridge Ltd
Co-authored papers 2
Institute of Genetics and Cancer, The University of Edinburgh MRC Human Genetics Unit
Co-authored papers 2
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 2
Telethon Kids Institute, University of Western Australia
Co-authored papers 2
Clinical Genetics, Addenbrooke's Hospital, Cambridge University Hospitals
Co-authored papers 2
University of Exeter, Royal Devon and Exeter Hospital
Co-authored papers 2
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 2
Department of Computer Sciences The University of Texas at Austin Austin
Co-authored papers 1
Institute of Cancer and Genetics, University of Edinburgh
Co-authored papers 1
University of Washington
Co-authored papers 1
Co-authored papers 1
Polytechnic Institute of Leiria
Co-authored papers 1
University of New South Wales
Co-authored papers 1
European Bioinformatics Institute
Co-authored papers 1
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Co-authored papers 1
University of Toronto
Co-authored papers 1
Berlin Institute for Medical Systems Biology
Co-authored papers 1
The University of Texas at Austin
Co-authored papers 1
International Society for Biocuration, Lawrence Berkeley National Laboratory, University of Edinburgh, University of Edinburgh School of Biological Sciences
Co-authored papers 1
Institute for Protein Research, Osaka University
Co-authored papers 1