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Author Details

Kimberly Stegmaier
Dana-Farber Cancer Institute
1995
148
50
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36658220The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.Nat Cell Biol2023
36398965Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors.Cancer Res2023
37747726EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes.Cancer Res2023
37595362PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.Blood2023
37648673DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia.Blood Adv2023
37725576Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.Clin Cancer Res2023
36823351Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.Nat Chem Biol2023
37066194Rapid-kinetics degron benchmarking reveals off-target activities and mixed agonism-antagonism of MYB inhibitors.bioRxiv2023
37000878Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.Sci Adv2023
37306107Phase 2 trial of palbociclib and ganitumab in patients with relapsed Ewing sarcoma.Cancer Med2023
36739349Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia.Leukemia2023
36993171Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops.bioRxiv2023
36658220The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.Nat Cell Biol2023
37595362PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.Blood2023
37747726EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes.Cancer Res2023
37648673DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia.Blood Adv2023
37725576Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.Clin Cancer Res2023
36993171Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops.bioRxiv2023
37306107Phase 2 trial of palbociclib and ganitumab in patients with relapsed Ewing sarcoma.Cancer Med2023
37000878Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.Sci Adv2023
37066194Rapid-kinetics degron benchmarking reveals off-target activities and mixed agonism-antagonism of MYB inhibitors.bioRxiv2023
36398965Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors.Cancer Res2023
36739349Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia.Leukemia2023
36823351Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.Nat Chem Biol2023
34341479Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.Leukemia2022
35710782Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia.Cell Death Dis2022
35709529Transcriptional Plasticity Drives Leukemia Immune Escape.Blood Cancer Discov2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
36040810VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system.JCI Insight2022
36221002Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.Br J Cancer2022
35817829Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1.Nat Cancer2022
35474100Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.Leukemia2022
35405016Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts.Cancer Discov2022
35534777IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia.Nat Cancer2022
34341479Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.Leukemia2022
35298000Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.Mol Cancer Res2022
34624079SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.Blood2022
35245447The proteogenomic subtypes of acute myeloid leukemia.Cancer Cell2022
34772733EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma.Cancer Discov2022
34531254An <i>In Vivo</i> CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.Cancer Discov2022
35710782Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia.Cell Death Dis2022
35709529Transcriptional Plasticity Drives Leukemia Immune Escape.Blood Cancer Discov2022
35474100Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.Leukemia2022
35405016Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts.Cancer Discov2022
35534777IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia.Nat Cancer2022
35817829Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1.Nat Cancer2022
36040810VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system.JCI Insight2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
36221002Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.Br J Cancer2022
35245447The proteogenomic subtypes of acute myeloid leukemia.Cancer Cell2022
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Collaborators

Dana-Farber Cancer Institute
Co-authored papers 42
Broad Institute of MIT and Harvard
Co-authored papers 28
University of Parma
Co-authored papers 19
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Co-authored papers 18
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Co-authored papers 17
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Co-authored papers 17
Universite de Paris, INSERM, CNRS
Co-authored papers 16
Co-authored papers 14
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Co-authored papers 14
Dana Farber Cancer Institute
Co-authored papers 14
Dana-Farber Cancer Institute
Co-authored papers 13
Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard
Co-authored papers 13
Dana-Farber Cancer Institute
Co-authored papers 11
Co-authored papers 11
The Ohio State University College of Medicine
Co-authored papers 10
Co-authored papers 9
Harvard Medical School
Co-authored papers 9
The Broad Institute of MIT and Harvard
Co-authored papers 9
Co-authored papers 9
Co-authored papers 9
Co-authored papers 8
Keck School of Medicine of the University of California los angeles
Co-authored papers 8
Broad Institute of Harvard and MIT
Co-authored papers 7
Co-authored papers 7
Broad Institute of Harvard and MIT
Co-authored papers 7
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Duke University School of Medicine Durham
Co-authored papers 7
Universite de Paris, Inserm CIC 1427
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Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Co-authored papers 6
Universite Paris Cite, INSERM, CNRS
Co-authored papers 6